BR9807365A - Composição para destruir células epiteliais de pigmento retinal e células proliferativas - Google Patents
Composição para destruir células epiteliais de pigmento retinal e células proliferativasInfo
- Publication number
- BR9807365A BR9807365A BR9807365-6A BR9807365A BR9807365A BR 9807365 A BR9807365 A BR 9807365A BR 9807365 A BR9807365 A BR 9807365A BR 9807365 A BR9807365 A BR 9807365A
- Authority
- BR
- Brazil
- Prior art keywords
- epithelial cells
- cells
- vitreous chamber
- retinal pigment
- pigment epithelial
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/645—Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/66—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid the modifying agent being a pre-targeting system involving a peptide or protein for targeting specific cells
- A61K47/665—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid the modifying agent being a pre-targeting system involving a peptide or protein for targeting specific cells the pre-targeting system, clearing therapy or rescue therapy involving biotin-(strept) avidin systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Nanotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Medical Informatics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
"COMPOSIçãO PARA DESTRUIR CéLULAS EPITELIAIS DE PIGMENTO RETINAL E CéLULAS PROLIFERATIVAS". Um método para destruir células epiteliais de pigmento retinal em um olho para evitar a ocorrência de vitreoretinopatia proliferativa. Uma solução contendo um agente ligante de membrana base conjugado a um agente citotóxico é introduzido na câmara vítrea. A solução é mantida na câmara vítrea por um período de tempo suficiente par permitir o agente ligante de membrana base se ligar a membranas base revestindo a câmara vítrea. A solução é então removida da câmara vítrea, através do que uma porção do agente ligante de membrana base permanece ligado a membranas base dentro da câmara vítrea, deste modo expondo células epiteliais de pigmento retinal dispostas na membrana base ao agente citotóxico.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3799497P | 1997-02-13 | 1997-02-13 | |
PCT/US1998/001408 WO1998035688A1 (en) | 1997-02-13 | 1998-01-28 | Method for destroying retinal pigment epithelial cells |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9807365A true BR9807365A (pt) | 2002-02-05 |
Family
ID=21897499
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9807365-6A BR9807365A (pt) | 1997-02-13 | 1998-01-28 | Composição para destruir células epiteliais de pigmento retinal e células proliferativas |
Country Status (8)
Country | Link |
---|---|
US (1) | US6138680A (pt) |
EP (1) | EP1027065A1 (pt) |
JP (1) | JP2002501483A (pt) |
CN (1) | CN1252001A (pt) |
AU (1) | AU723614B2 (pt) |
BR (1) | BR9807365A (pt) |
CA (1) | CA2281690A1 (pt) |
WO (1) | WO1998035688A1 (pt) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6106554A (en) * | 1999-02-25 | 2000-08-22 | Bausch & Lomb Surgical, Inc. | Intraocular lens implants for the prevention of secondary cataracts |
KR100398783B1 (ko) * | 1999-06-15 | 2003-09-19 | 가부시키가이샤 엔.티.티.도코모 | 인접 기지국 정보 갱신 방법, 이동 통신 시스템, 이동국, 기지국 및 제어국 |
WO2000078359A2 (en) * | 1999-06-21 | 2000-12-28 | George Tuszynski | Compositions for treating chemotherapy-resistant tumor cells |
US6380161B1 (en) | 1999-06-21 | 2002-04-30 | Inkine Pharmaceutical Company, Inc. | Compositions for treating chemotherapy-resistant tumor cells and targeted chemotherapy compositions |
US6558419B1 (en) * | 2001-11-08 | 2003-05-06 | Bausch & Lomb Incorporated | Intraocular lens |
ES2726804T3 (es) * | 2011-02-25 | 2019-10-09 | Riken | Método de producción de lámina de células epiteliales de pigmento retiniano |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4920104A (en) * | 1988-05-16 | 1990-04-24 | Medchem Products, Inc. | Sodium hyaluronate composition |
-
1998
- 1998-01-28 BR BR9807365-6A patent/BR9807365A/pt not_active IP Right Cessation
- 1998-01-28 CA CA002281690A patent/CA2281690A1/en not_active Abandoned
- 1998-01-28 US US09/014,492 patent/US6138680A/en not_active Expired - Fee Related
- 1998-01-28 AU AU59307/98A patent/AU723614B2/en not_active Ceased
- 1998-01-28 WO PCT/US1998/001408 patent/WO1998035688A1/en not_active Application Discontinuation
- 1998-01-28 EP EP98902715A patent/EP1027065A1/en not_active Withdrawn
- 1998-01-28 JP JP53575598A patent/JP2002501483A/ja active Pending
- 1998-01-28 CN CN98804065A patent/CN1252001A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
US6138680A (en) | 2000-10-31 |
JP2002501483A (ja) | 2002-01-15 |
WO1998035688A1 (en) | 1998-08-20 |
CN1252001A (zh) | 2000-05-03 |
AU5930798A (en) | 1998-09-08 |
AU723614B2 (en) | 2000-08-31 |
CA2281690A1 (en) | 1998-08-20 |
EP1027065A1 (en) | 2000-08-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE 5A, 6A,7A,8A E 9A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1887 DE 06/03/2007. |