BR9714133A - isolated nucleic acid, molecule thereof, probe, recombinant expression vector, cell, polypeptide, fusion protein vaccine formulation and processes for producing a h. pylori, to detect the presence of a helicobacter nucleic acid in a sample, to treat or reduce a risk of infection by h. pylori in an individual and to produce a vaccine formulation - Google Patents
isolated nucleic acid, molecule thereof, probe, recombinant expression vector, cell, polypeptide, fusion protein vaccine formulation and processes for producing a h. pylori, to detect the presence of a helicobacter nucleic acid in a sample, to treat or reduce a risk of infection by h. pylori in an individual and to produce a vaccine formulationInfo
- Publication number
- BR9714133A BR9714133A BR9714133-0A BR9714133A BR9714133A BR 9714133 A BR9714133 A BR 9714133A BR 9714133 A BR9714133 A BR 9714133A BR 9714133 A BR9714133 A BR 9714133A
- Authority
- BR
- Brazil
- Prior art keywords
- pylori
- nucleic acid
- vaccine formulation
- polypeptide
- produce
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 6
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 6
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 6
- 239000000203 mixture Substances 0.000 title abstract 5
- 238000009472 formulation Methods 0.000 title abstract 4
- 102000039446 nucleic acids Human genes 0.000 title abstract 4
- 108020004707 nucleic acids Proteins 0.000 title abstract 4
- 150000007523 nucleic acids Chemical class 0.000 title abstract 4
- 239000000523 sample Substances 0.000 title abstract 4
- 229960005486 vaccine Drugs 0.000 title abstract 4
- 239000013604 expression vector Substances 0.000 title abstract 2
- 108020001507 fusion proteins Proteins 0.000 title abstract 2
- 208000015181 infectious disease Diseases 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 238000003259 recombinant expression Methods 0.000 title abstract 2
- 241000589989 Helicobacter Species 0.000 title 1
- 102000037865 fusion proteins Human genes 0.000 title 1
- 229940023143 protein vaccine Drugs 0.000 title 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 238000002864 sequence alignment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/205—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Campylobacter (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K2039/106—Vibrio; Campylobacter; Not used, see subgroups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Abstract
"áCIDO NUCLEICO ISOLADO, MOLéCULA DO MESMO, SONDA, VETOR DE EXPRESSãO RECOMBINANTE, CéLULA, POLIPEPTìDEO, PROTEìNA DE FUSãO, FORMULAçãO DE VACINA E PROCESSOS PARA PRODUZIR UM POLIPEPTìDEO DE H. PYLORI, PARA DETECTAR A PRESENçA DE UM áCIDO NUCLEICO DE HELICOBACTER EM UMA AMOSTRA, PARA TRATAR OU REDUZIR UM RISCO DE INFECçãO POR H. PYLORI EM UM INDIVìDUO E PARA PRODUZIR UMA FORMULAçãO DE VACINA". Descreve-se preparações recombinantes ou substancialmente puras de polipeptídeos de H. pylori. Os ácidos nucleicos que codificam os polipeptídeos também são descritos. Os polipeptídeos de H. pylori são úteis para diagnósticos e composições de vacina, sendo que a figura representa um alinhamento de sequências de aminoácidos de cinco proteínas de H. pylori."NUCLEIC ACID ISOLATED, MOLECULE OF THE SAME, PROBE, RECOMBINANT EXPRESSION VECTOR, CELL, POLYPEPTIDE, FUSION PROTEIN, VACCINE FORMULATION AND PROCESSES TO PRODUCE A POLYPEPTIDE OF H. PYLORIC HERICHERIC UTERA UTERA SAMPLE, TO TREAT OR REDUCE A RISK OF H. PYLORI INFECTION IN AN INDIVIDUAL AND TO PRODUCE A VACCINE FORMULATION ". Recombinant or substantially pure preparations of H. pylori polypeptides are described. Nucleic acids encoding polypeptides are also described. H. pylori polypeptides are useful for vaccine diagnostics and compositions, the figure representing an amino acid sequence alignment of five H. pylori proteins.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75962596A | 1996-12-05 | 1996-12-05 | |
| US82374597A | 1997-03-25 | 1997-03-25 | |
| US89192897A | 1997-07-14 | 1997-07-14 | |
| PCT/US1997/022104 WO1998024475A1 (en) | 1996-12-05 | 1997-12-05 | Nucleic acid and amino acid sequences relating to helicobacter pylori and vaccine compositions thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9714133A true BR9714133A (en) | 2000-02-29 |
Family
ID=27419527
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9714133-0A BR9714133A (en) | 1996-12-05 | 1997-12-05 | isolated nucleic acid, molecule thereof, probe, recombinant expression vector, cell, polypeptide, fusion protein vaccine formulation and processes for producing a h. pylori, to detect the presence of a helicobacter nucleic acid in a sample, to treat or reduce a risk of infection by h. pylori in an individual and to produce a vaccine formulation |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0964699A4 (en) |
| JP (1) | JP2001510992A (en) |
| KR (1) | KR20000069297A (en) |
| CN (1) | CN1246799A (en) |
| AR (1) | AR010337A1 (en) |
| AU (1) | AU739641B2 (en) |
| BR (1) | BR9714133A (en) |
| CA (1) | CA2273199A1 (en) |
| EE (1) | EE9900226A (en) |
| ID (1) | ID21946A (en) |
| IL (1) | IL129746A0 (en) |
| IS (1) | IS5047A (en) |
| NO (1) | NO992158L (en) |
| NZ (1) | NZ335633A (en) |
| PL (1) | PL333943A1 (en) |
| SK (1) | SK57999A3 (en) |
| TR (1) | TR199901262T2 (en) |
| WO (1) | WO1998024475A1 (en) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5043254B2 (en) * | 1998-10-26 | 2012-10-10 | ノボザイムス アクティーゼルスカブ | Production and screening of DNA libraries of interest in filamentous cells |
| US7034132B2 (en) | 2001-06-04 | 2006-04-25 | Anderson David W | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
| AUPQ347199A0 (en) * | 1999-10-15 | 1999-11-11 | Csl Limited | Novel polypeptide fragments |
| US6951729B1 (en) | 1999-10-27 | 2005-10-04 | Affinium Pharmaceuticals, Inc. | High throughput screening method for biological agents affecting fatty acid biosynthesis |
| US7048926B2 (en) | 2000-10-06 | 2006-05-23 | Affinium Pharmaceuticals, Inc. | Methods of agonizing and antagonizing FabK |
| WO2002031128A1 (en) * | 2000-10-06 | 2002-04-18 | Smithkline Beecham Corporation | Methods of agonizing and antagonizing fabk |
| WO2002066502A1 (en) * | 2001-02-21 | 2002-08-29 | Boren Thomas | Helicobacter pylori sialic acid binding adhesin, saba and saba - gene |
| KR20110069859A (en) * | 2008-10-08 | 2011-06-23 | 이뮨 솔루션즈 리미티드 | Oral vaccines for producing mucosal immunity |
| JP6959937B2 (en) * | 2015-12-14 | 2021-11-05 | テクニシェ ユニバーシタット ミュンヘン | Helicobacter pylori vaccine |
| CN110343697A (en) * | 2019-08-05 | 2019-10-18 | 湖州三零科技股份有限公司 | A kind of plant disease fungus Total DNA extraction method |
| CN113435168B (en) * | 2021-06-10 | 2024-03-22 | 上海美吉生物医药科技有限公司 | Automatic editing method, system, terminal and medium for glue pattern |
| CN114057854B (en) * | 2021-09-30 | 2022-07-15 | 河北医科大学第四医院 | Helicobacter pylori CD4+T cell tolerance polypeptide fusion antigen and application thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9300139L (en) * | 1993-01-19 | 1994-07-20 | Medicarb Ab | Preparation of a new drug |
-
1997
- 1997-12-05 AR ARP970105740A patent/AR010337A1/en not_active Application Discontinuation
- 1997-12-05 WO PCT/US1997/022104 patent/WO1998024475A1/en not_active Application Discontinuation
- 1997-12-05 CN CN97181630A patent/CN1246799A/en active Pending
- 1997-12-05 TR TR1999/01262T patent/TR199901262T2/en unknown
- 1997-12-05 EE EEP199900226A patent/EE9900226A/en unknown
- 1997-12-05 JP JP52575898A patent/JP2001510992A/en active Pending
- 1997-12-05 CA CA002273199A patent/CA2273199A1/en not_active Abandoned
- 1997-12-05 AU AU58954/98A patent/AU739641B2/en not_active Ceased
- 1997-12-05 NZ NZ335633A patent/NZ335633A/en unknown
- 1997-12-05 BR BR9714133-0A patent/BR9714133A/en not_active IP Right Cessation
- 1997-12-05 IL IL12974697A patent/IL129746A0/en unknown
- 1997-12-05 KR KR1019997004955A patent/KR20000069297A/en not_active Application Discontinuation
- 1997-12-05 EP EP97954525A patent/EP0964699A4/en not_active Withdrawn
- 1997-12-05 SK SK579-99A patent/SK57999A3/en unknown
- 1997-12-05 ID IDW990495A patent/ID21946A/en unknown
- 1997-12-05 PL PL97333943A patent/PL333943A1/en unknown
-
1999
- 1999-05-04 NO NO992158A patent/NO992158L/en not_active Application Discontinuation
- 1999-05-10 IS IS5047A patent/IS5047A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SK57999A3 (en) | 2000-05-16 |
| NO992158L (en) | 1999-07-05 |
| EE9900226A (en) | 1999-12-15 |
| EP0964699A1 (en) | 1999-12-22 |
| AU5895498A (en) | 1998-06-29 |
| IL129746A0 (en) | 2000-02-29 |
| TR199901262T2 (en) | 1999-08-23 |
| CA2273199A1 (en) | 1998-06-11 |
| EP0964699A4 (en) | 2005-04-06 |
| WO1998024475A1 (en) | 1998-06-11 |
| KR20000069297A (en) | 2000-11-25 |
| ID21946A (en) | 1999-08-12 |
| JP2001510992A (en) | 2001-08-07 |
| CN1246799A (en) | 2000-03-08 |
| AR010337A1 (en) | 2000-06-07 |
| NZ335633A (en) | 2000-10-27 |
| IS5047A (en) | 1999-05-10 |
| PL333943A1 (en) | 2000-01-31 |
| NO992158D0 (en) | 1999-05-04 |
| AU739641B2 (en) | 2001-10-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A,7A E 8A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1833 DE 21/02/2006. |