AR010337A1 - ISOLATED NUCLEIC ACID, NUCLEIC ACID MOLECULA, PROBE, RECOMBINANT EXPRESSION VECTOR, CELL, METHOD FOR PRODUCING A POLYPEPTIDE OF H.PYLORI, METHOD FOR DETECTING THE PRESENCE OF A NUCLEIC ACID HELICOBACTER, POLIPE FORMULATION FOR VACCINE - Google Patents

ISOLATED NUCLEIC ACID, NUCLEIC ACID MOLECULA, PROBE, RECOMBINANT EXPRESSION VECTOR, CELL, METHOD FOR PRODUCING A POLYPEPTIDE OF H.PYLORI, METHOD FOR DETECTING THE PRESENCE OF A NUCLEIC ACID HELICOBACTER, POLIPE FORMULATION FOR VACCINE

Info

Publication number
AR010337A1
AR010337A1 ARP970105740A ARP970105740A AR010337A1 AR 010337 A1 AR010337 A1 AR 010337A1 AR P970105740 A ARP970105740 A AR P970105740A AR P970105740 A ARP970105740 A AR P970105740A AR 010337 A1 AR010337 A1 AR 010337A1
Authority
AR
Argentina
Prior art keywords
nucleic acid
pylori
polypeptide
producing
vaccine
Prior art date
Application number
ARP970105740A
Other languages
Spanish (es)
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of AR010337A1 publication Critical patent/AR010337A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/205Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Campylobacter (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K2039/106Vibrio; Campylobacter; Not used, see subgroups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Un ácido nucleico aislado que comprende una secuencia nucleotídica que codifica un polipéptido de H.pylori que es por lo menos aproximadamente 60%homologa con una secuencia de animoácido seleccionada del grupo que consiste en SEC ID N* 98-SECID N* 194; ácido nucleico aislado, molécula de ácido nucleico,sonda, vector de expresion recombinante, célula, método para producir un polipéptido de H. Pylori, método para detectar la presencia de un ácidonucleico helicobacter, polipéptidode H . pylori aislado, proteína de fusion, formulacion para vacuna para tratamiento profiláctico o terapéutico de unainfeccion de H.pylori, método para tratar o reducir un riesgo de contraer la infeccion de H,pylori, método para producir unaformula cion para vacuna ypolipéptido de H.pylori quimérico.An isolated nucleic acid comprising a nucleotide sequence encoding an H.pylori polypeptide that is at least about 60% homologous to an amino acid sequence selected from the group consisting of SEQ ID N * 98-SECID N * 194; isolated nucleic acid, nucleic acid molecule, probe, recombinant expression vector, cell, method of producing an H. pylori polypeptide, method of detecting the presence of a helicobacter nucleic acid, H polypeptide. isolated pylori, fusion protein, vaccine formulation for prophylactic or therapeutic treatment of H. pylori infection, method of treating or reducing a risk of contracting H infection, pylori, method of producing a formulation for H.pylori vaccine and polypeptide chimerical.

ARP970105740A 1996-12-05 1997-12-05 ISOLATED NUCLEIC ACID, NUCLEIC ACID MOLECULA, PROBE, RECOMBINANT EXPRESSION VECTOR, CELL, METHOD FOR PRODUCING A POLYPEPTIDE OF H.PYLORI, METHOD FOR DETECTING THE PRESENCE OF A NUCLEIC ACID HELICOBACTER, POLIPE FORMULATION FOR VACCINE AR010337A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US75962596A 1996-12-05 1996-12-05
US82374597A 1997-03-25 1997-03-25
US89192897A 1997-07-14 1997-07-14

Publications (1)

Publication Number Publication Date
AR010337A1 true AR010337A1 (en) 2000-06-07

Family

ID=27419527

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP970105740A AR010337A1 (en) 1996-12-05 1997-12-05 ISOLATED NUCLEIC ACID, NUCLEIC ACID MOLECULA, PROBE, RECOMBINANT EXPRESSION VECTOR, CELL, METHOD FOR PRODUCING A POLYPEPTIDE OF H.PYLORI, METHOD FOR DETECTING THE PRESENCE OF A NUCLEIC ACID HELICOBACTER, POLIPE FORMULATION FOR VACCINE

Country Status (18)

Country Link
EP (1) EP0964699A4 (en)
JP (1) JP2001510992A (en)
KR (1) KR20000069297A (en)
CN (1) CN1246799A (en)
AR (1) AR010337A1 (en)
AU (1) AU739641B2 (en)
BR (1) BR9714133A (en)
CA (1) CA2273199A1 (en)
EE (1) EE9900226A (en)
ID (1) ID21946A (en)
IL (1) IL129746A0 (en)
IS (1) IS5047A (en)
NO (1) NO992158L (en)
NZ (1) NZ335633A (en)
PL (1) PL333943A1 (en)
SK (1) SK57999A3 (en)
TR (1) TR199901262T2 (en)
WO (1) WO1998024475A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000024883A1 (en) * 1998-10-26 2000-05-04 Novozymes A/S Constructing and screening a dna library of interest in filamentous fungal cells
US7034132B2 (en) 2001-06-04 2006-04-25 Anderson David W Therapeutic polypeptides, nucleic acids encoding same, and methods of use
AUPQ347199A0 (en) * 1999-10-15 1999-11-11 Csl Limited Novel polypeptide fragments
US6951729B1 (en) 1999-10-27 2005-10-04 Affinium Pharmaceuticals, Inc. High throughput screening method for biological agents affecting fatty acid biosynthesis
WO2002031128A1 (en) * 2000-10-06 2002-04-18 Smithkline Beecham Corporation Methods of agonizing and antagonizing fabk
US7048926B2 (en) 2000-10-06 2006-05-23 Affinium Pharmaceuticals, Inc. Methods of agonizing and antagonizing FabK
WO2002066502A1 (en) * 2001-02-21 2002-08-29 Boren Thomas Helicobacter pylori sialic acid binding adhesin, saba and saba - gene
EP2344152A4 (en) * 2008-10-08 2013-04-03 Immune Solutions Ltd Oral vaccines for producing mucosal immunity
JP6959937B2 (en) * 2015-12-14 2021-11-05 テクニシェ ユニバーシタット ミュンヘン Helicobacter pylori vaccine
CN110343697B (en) * 2019-08-05 2024-07-12 南京昊斯亭网络科技有限公司 Method for extracting total DNA of plant disease bacteria
CN113435168B (en) * 2021-06-10 2024-03-22 上海美吉生物医药科技有限公司 Automatic editing method, system, terminal and medium for glue pattern
CN114057854B (en) * 2021-09-30 2022-07-15 河北医科大学第四医院 Helicobacter pylori CD4+T cell tolerance polypeptide fusion antigen and application thereof
CN116162140A (en) * 2022-07-19 2023-05-26 四川大学华西医院 Helicobacter pylori recombinant antigen protein SecG, and preparation method and application thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9300139L (en) * 1993-01-19 1994-07-20 Medicarb Ab Preparation of a new drug

Also Published As

Publication number Publication date
NO992158L (en) 1999-07-05
KR20000069297A (en) 2000-11-25
IL129746A0 (en) 2000-02-29
NO992158D0 (en) 1999-05-04
TR199901262T2 (en) 1999-08-23
EP0964699A1 (en) 1999-12-22
IS5047A (en) 1999-05-10
NZ335633A (en) 2000-10-27
EE9900226A (en) 1999-12-15
BR9714133A (en) 2000-02-29
SK57999A3 (en) 2000-05-16
AU5895498A (en) 1998-06-29
ID21946A (en) 1999-08-12
JP2001510992A (en) 2001-08-07
EP0964699A4 (en) 2005-04-06
CN1246799A (en) 2000-03-08
WO1998024475A1 (en) 1998-06-11
AU739641B2 (en) 2001-10-18
PL333943A1 (en) 2000-01-31
CA2273199A1 (en) 1998-06-11

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