SE9300139L - Preparation of a new drug - Google Patents

Preparation of a new drug

Info

Publication number
SE9300139L
SE9300139L SE9300139A SE9300139A SE9300139L SE 9300139 L SE9300139 L SE 9300139L SE 9300139 A SE9300139 A SE 9300139A SE 9300139 A SE9300139 A SE 9300139A SE 9300139 L SE9300139 L SE 9300139L
Authority
SE
Sweden
Prior art keywords
sulphate
pylori
protein
prophylaxis
heparin
Prior art date
Application number
SE9300139A
Other languages
Unknown language ( )
Swedish (sv)
Other versions
SE9300139D0 (en
Inventor
Olle Larm
Torkel Wadstroem
Original Assignee
Medicarb Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medicarb Ab filed Critical Medicarb Ab
Priority to SE9300139A priority Critical patent/SE9300139L/en
Publication of SE9300139D0 publication Critical patent/SE9300139D0/en
Priority to AU58944/94A priority patent/AU5894494A/en
Priority to PCT/SE1994/000021 priority patent/WO1994016714A1/en
Publication of SE9300139L publication Critical patent/SE9300139L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

The use of a composition in the preparation of a drug for the treatment or prophylaxis of infections caused by or associated with Helicobacter pylori, said composition containing as an active constituent an immobilized, negatively charged polysaccharide selected from the group comprising: heparin, heparan sulphate and dextran sulphate; a method of treating or preventing infections caused by or associated with Helicobacter pylori in mammals including man, comprising administering to a mammal in need of such treatment or prophylaxis an effective amount of a composition containing as an active constituent an immobilized, negatively charged polysaccharide selected from the group comprising: heparin, heparan sulphate and dextran sulphate; a protein with an apparent molecular weight of not more than about 120 kDa (on SDS-PAGE) and active subfragments thereof down to a molecular weight of about 20 kDa, said protein and subfragments specifically binding to heparan sulphate and being producible from H. pylori strains 25 and 1139 as a surface protein antigen thereof; mono- and polyclonal antibodies; process for detecting H. pylori; drug compositions; reagent kit; and a vaccine.
SE9300139A 1993-01-19 1993-01-19 Preparation of a new drug SE9300139L (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
SE9300139A SE9300139L (en) 1993-01-19 1993-01-19 Preparation of a new drug
AU58944/94A AU5894494A (en) 1993-01-19 1994-01-14 The use of a composition for the treatment of infections caused by helicobacter pylori
PCT/SE1994/000021 WO1994016714A1 (en) 1993-01-19 1994-01-14 The use of a composition for the treatment of infections caused by helicobacter pylori

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9300139A SE9300139L (en) 1993-01-19 1993-01-19 Preparation of a new drug

Publications (2)

Publication Number Publication Date
SE9300139D0 SE9300139D0 (en) 1993-01-19
SE9300139L true SE9300139L (en) 1994-07-20

Family

ID=20388583

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9300139A SE9300139L (en) 1993-01-19 1993-01-19 Preparation of a new drug

Country Status (3)

Country Link
AU (1) AU5894494A (en)
SE (1) SE9300139L (en)
WO (1) WO1994016714A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE518597C2 (en) * 1994-05-04 2002-10-29 Medicarb Ab Use of chitosan in combination with a sulfated, negatively charged polysaccharide for the preparation of a dental active oral hygiene composition for the treatment of periodontitis, plaques and / or caries
ID22065A (en) * 1996-10-28 1999-08-26 Astra Ab NUCLEIC ACID AND AMINO ACID CONNECTED TO HELICOBACTER PYLORI AND VACCINE COMPOSITIONS FROM SUCH ACID CONSTRUCTION
AU739641B2 (en) * 1996-12-05 2001-10-18 Astra Aktiebolag Nucleic acid and amino acid sequences relating to helicobacter pylori and vaccine compositions thereof
SE508760C2 (en) 1997-04-29 1998-11-02 Medicarb Ab Use of a composition comprising chitosan in combination with a polysaccharide, as an active component in a solvent, for the preparation of a dairy dipping agent for milk producing animals
EP1002805A4 (en) * 1998-06-09 2003-01-29 Gen Corp Kk Fixation inhibitors for helicobacter pylori
CN102641496A (en) 2011-02-16 2012-08-22 辛绍祺 New application and composition of high-molecular polymer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5116821A (en) * 1990-11-20 1992-05-26 The Procter & Gamble Company Sulfated glyceroglucolipids as inhibitors of bacterial adherence
IT1249060B (en) * 1991-05-24 1995-02-11 Bononi Ricerca TOPICAL PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF CICATRIZATION AND RE-EPITELIZATION OF CHRONIC PHLEBOSTATIC ULCERS.

Also Published As

Publication number Publication date
SE9300139D0 (en) 1993-01-19
WO1994016714A1 (en) 1994-08-04
AU5894494A (en) 1994-08-15

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