BR9711078A - Método para modificar as especificações de comprimento de cadeia e de posições de uma desaturase e desaturase de acila-acp modificada. - Google Patents

Método para modificar as especificações de comprimento de cadeia e de posições de uma desaturase e desaturase de acila-acp modificada.

Info

Publication number
BR9711078A
BR9711078A BR9711078-7A BR9711078A BR9711078A BR 9711078 A BR9711078 A BR 9711078A BR 9711078 A BR9711078 A BR 9711078A BR 9711078 A BR9711078 A BR 9711078A
Authority
BR
Brazil
Prior art keywords
desaturase
modifying
chain length
fatty acid
acp
Prior art date
Application number
BR9711078-7A
Other languages
English (en)
Inventor
John Shanklin
Gunter Schneider
Ylva Lindqvist
Edgar Cahoon
Original Assignee
Brookhaven Science Ass Llc
Karolinska Innovations Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brookhaven Science Ass Llc, Karolinska Innovations Ab filed Critical Brookhaven Science Ass Llc
Publication of BR9711078A publication Critical patent/BR9711078A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0083—Miscellaneous (1.14.99)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Nutrition Science (AREA)
  • Biophysics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

"MéTODO PARA MODIFICAR AS ESPECIFICAçõES DE COMPRIMENTO DE CADEIA E DE POSIçõES DE UMA DESATURASE E DESATURASE DE ACILA-ACP MODIFICADA", é divulgado um método para modificar as especificidades de comprimento de cadeia e de posições de cadeias duplas de uma desaturase de ácidos graxos vegetais solúvel. Mais especificamente, o método envolve modificar resíduos de contato de aminoácido no canal de ligação a substrato da desaturase de ácido graxo solúvel que contactam o ácido graxo. Divulga-se especificamente a modificação de uma desaturase de acila-ACP. Os resíduos de contato de aminoácido que jazem dentro do canal de ligação a substrato são identificados e subseq³entemente substituídos por diferentes resíduos, para efetuar a modificação de atividade.
BR9711078-7A 1996-08-14 1997-08-01 Método para modificar as especificações de comprimento de cadeia e de posições de uma desaturase e desaturase de acila-acp modificada. BR9711078A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/689,823 US5705391A (en) 1996-08-14 1996-08-14 Modified acyl-ACP desaturase
PCT/US1997/013690 WO1998006735A1 (en) 1996-08-14 1997-08-01 Modified acyl-acp desaturase

Publications (1)

Publication Number Publication Date
BR9711078A true BR9711078A (pt) 2000-01-11

Family

ID=24770011

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9711078-7A BR9711078A (pt) 1996-08-14 1997-08-01 Método para modificar as especificações de comprimento de cadeia e de posições de uma desaturase e desaturase de acila-acp modificada.

Country Status (15)

Country Link
US (3) US5705391A (pt)
EP (1) EP0934332A4 (pt)
JP (1) JP2000516092A (pt)
AU (1) AU718200B2 (pt)
BR (1) BR9711078A (pt)
CA (1) CA2263281C (pt)
EE (1) EE04020B1 (pt)
HU (1) HUP9904364A3 (pt)
IL (1) IL128498A0 (pt)
NO (1) NO990669L (pt)
NZ (1) NZ334616A (pt)
PL (1) PL331616A1 (pt)
RU (1) RU2228356C2 (pt)
UA (1) UA72180C2 (pt)
WO (1) WO1998006735A1 (pt)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6310194B1 (en) 1994-09-26 2001-10-30 Carnegie Institution Of Washington Plant fatty acid hydroxylases
US5705391A (en) * 1996-08-14 1998-01-06 Associated Universities, Inc. Modified acyl-ACP desaturase
BR9910125A (pt) * 1998-04-16 2003-02-25 Pierre Broun Interconversão de dessaturases e hidroxilases de ácido graxo de plantas
US6686186B2 (en) * 1999-01-19 2004-02-03 Brookhaven Science Associates Llc Mutant fatty acid desaturase
US7323335B2 (en) * 1999-01-19 2008-01-29 Brookhaven Science Associates, Llc Mutant fatty acid desaturase and methods for directed mutagenesis
JP4660041B2 (ja) * 1999-06-09 2011-03-30 ブルツクヘブン・サイエンス・アソシエイツ・エルエルシー 突然変異体の脂肪酸デサチュラーゼおよび特異的突然変異誘発の方法
US6221668B1 (en) 1999-08-20 2001-04-24 Streck Laboratories, Inc. Hematology control and system for multi-parameter hematology measurements
US6200500B1 (en) 1999-08-20 2001-03-13 Streck Laboratories, Inc. Hematology control and system for multi-parameter hematology measurements
US6780405B1 (en) * 2000-04-28 2004-08-24 Avant Immunotherapeutics, Inc. Regulated antigen delivery system (RADS)
US6872547B1 (en) 2000-10-11 2005-03-29 Washington University Functional balanced-lethal host-vector systems
US20040137003A1 (en) * 2001-04-30 2004-07-15 Curtiss Iii Roy Regulated antigen delivery system (rads)
US6653137B2 (en) 2001-12-03 2003-11-25 Streck Laboratories Inc. Hematology reference control
US6723563B2 (en) 2001-12-03 2004-04-20 Streck Laboratories Inc. Hematology reference control
EP2216405A1 (en) 2002-05-03 2010-08-11 Monsanto Technology LLC Speed specific USP promoters for expressing genes in plants
US7078234B2 (en) 2002-12-18 2006-07-18 Monsanto Technology Llc Maize embryo-specific promoter compositions and methods for use thereof
AU2004225483B2 (en) 2003-03-28 2009-07-23 Monsanto Technology, Llc Novel plant promoters for use in early seed development
WO2006089950A2 (en) 2005-02-26 2006-08-31 Basf Plant Science Gmbh Expression cassettes for seed-preferential expression in plants
ATE552343T1 (de) 2005-04-19 2012-04-15 Basf Plant Science Gmbh Endosperm-spezifische expression und/oder expression in keimenden embryos monokotyledoner pflanzen
AU2006237346B2 (en) 2005-04-20 2011-04-07 Basf Plant Science Gmbh Expression cassettes for seed-preferential expression in plants
AU2006245701B2 (en) 2005-05-10 2011-04-28 Basf Plant Science Gmbh Expression cassettes for seed-preferential expression in plants
EP1837397A1 (en) * 2006-03-21 2007-09-26 Monsanto S.A.S. FAD-2 mutants and high oleic plants
AU2008214568B2 (en) 2007-02-16 2013-04-18 Basf Plant Science Gmbh Nucleic acid sequences for regulation of embryo-specific expression in monocotyledonous plants
CA2756146C (en) 2009-04-22 2018-12-04 Basf Plant Science Company Gmbh Whole seed specific promoter
AU2010270309A1 (en) 2009-07-10 2012-02-02 Basf Plant Science Company Gmbh Expression cassettes for endosperm-specific expression in plants
DE112010005958T5 (de) 2009-12-03 2013-08-14 Basf Plant Science Company Gmbh Expressionskassetten für die Embryo-spezifische Expression in Pflanzen

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0537178T4 (da) * 1990-05-25 2007-07-16 Du Pont Nukleotidsekvens af sojabönne-stearoyl-ACP-desaturase-gen
CA2099619C (en) * 1990-12-20 2005-03-29 William D. Hitz Nucleotide sequences of soybean acyl-acp thioesterase genes
US5654402A (en) * 1994-10-26 1997-08-05 Michigan State University Methods and compositions relating to plant Δ6 palmitoyl-acyl carrier protein desaturase
US5705391A (en) * 1996-08-14 1998-01-06 Associated Universities, Inc. Modified acyl-ACP desaturase

Also Published As

Publication number Publication date
JP2000516092A (ja) 2000-12-05
NZ334616A (en) 1999-04-29
US5705391A (en) 1998-01-06
CA2263281A1 (en) 1998-02-19
NO990669D0 (no) 1999-02-12
WO1998006735A1 (en) 1998-02-19
HUP9904364A2 (hu) 2000-04-28
EP0934332A1 (en) 1999-08-11
PL331616A1 (en) 1999-08-02
EE9900063A (et) 1999-10-15
RU2228356C2 (ru) 2004-05-10
US5888790A (en) 1999-03-30
EP0934332A4 (en) 2001-11-21
US6100091A (en) 2000-08-08
HUP9904364A3 (en) 2001-10-29
AU718200B2 (en) 2000-04-06
EE04020B1 (et) 2003-04-15
UA72180C2 (uk) 2005-02-15
CA2263281C (en) 2009-10-13
IL128498A0 (en) 2000-01-31
AU3826697A (en) 1998-03-06
NO990669L (no) 1999-04-12

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A,9 E 10A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1912 DE 28/08/2007.