BR9708721A - Processo para a preparação de uma formulação granular para compressão em tabletes farmacêuticos composição granular esférica substancialmente porosa e tabletes farmacêuticos comprimidos - Google Patents

Processo para a preparação de uma formulação granular para compressão em tabletes farmacêuticos composição granular esférica substancialmente porosa e tabletes farmacêuticos comprimidos

Info

Publication number
BR9708721A
BR9708721A BR9708721A BR9708721A BR9708721A BR 9708721 A BR9708721 A BR 9708721A BR 9708721 A BR9708721 A BR 9708721A BR 9708721 A BR9708721 A BR 9708721A BR 9708721 A BR9708721 A BR 9708721A
Authority
BR
Brazil
Prior art keywords
pharmaceutical tablets
compression
preparation
granular
porous spherical
Prior art date
Application number
BR9708721A
Other languages
English (en)
Inventor
Marc S Karetny
Original Assignee
Fmc Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fmc Corp filed Critical Fmc Corp
Publication of BR9708721A publication Critical patent/BR9708721A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
BR9708721A 1996-04-17 1997-04-15 Processo para a preparação de uma formulação granular para compressão em tabletes farmacêuticos composição granular esférica substancialmente porosa e tabletes farmacêuticos comprimidos BR9708721A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/785,228 US5858409A (en) 1996-04-17 1996-04-17 Hydrolyzed cellulose granulations for pharmaceuticals
PCT/US1997/006313 WO1997038678A1 (en) 1996-04-17 1997-04-15 Hydrolyzed cellulose granulations for pharmaceuticals

Publications (1)

Publication Number Publication Date
BR9708721A true BR9708721A (pt) 1999-08-03

Family

ID=25134825

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9708721A BR9708721A (pt) 1996-04-17 1997-04-15 Processo para a preparação de uma formulação granular para compressão em tabletes farmacêuticos composição granular esférica substancialmente porosa e tabletes farmacêuticos comprimidos

Country Status (12)

Country Link
US (1) US5858409A (pt)
EP (1) EP0942715A4 (pt)
KR (1) KR20000005514A (pt)
AU (1) AU2671597A (pt)
BR (1) BR9708721A (pt)
EA (1) EA000853B1 (pt)
IL (1) IL126496A (pt)
NO (1) NO326912B1 (pt)
NZ (1) NZ332295A (pt)
TW (1) TW541180B (pt)
WO (1) WO1997038678A1 (pt)
ZA (1) ZA973031B (pt)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6471994B1 (en) 1995-01-09 2002-10-29 Edward Mendell Co., Inc. Pharmaceutical excipient having improved compressibility
US6936277B2 (en) * 1995-01-09 2005-08-30 J. Rettenmaier & Soehne Gmbh & Co. Kg Pharmaceutical excipient having improved compressibility
US6106865A (en) * 1995-01-09 2000-08-22 Edward Mendell Co., Inc. Pharmaceutical excipient having improved compressibility
US5585115A (en) 1995-01-09 1996-12-17 Edward H. Mendell Co., Inc. Pharmaceutical excipient having improved compressability
US6395303B1 (en) 1996-06-10 2002-05-28 Edward Mendell Co., Inc. Process for preparing a directly compressible solid dosage form containing microcrystalline cellulose
US5955107A (en) * 1997-12-12 1999-09-21 Fmc Corporation Pharmaceutical suspension tablet compositions
US6232351B1 (en) 1998-05-22 2001-05-15 Amway Corporation Co-processed botanical plant composition
US6211246B1 (en) * 1999-06-10 2001-04-03 Mcneil-Ppc, Inc. Rapidly absorbed liquid compositions
US6143285A (en) * 1999-06-23 2000-11-07 Combe Incorporated Body powder composition
US6555139B2 (en) 1999-06-28 2003-04-29 Wockhardt Europe Limited Preparation of micron-size pharmaceutical particles by microfluidization
DK1233755T3 (da) * 1999-09-29 2007-10-29 Scherer Technologies Inc R P Hydrolyseret cellulosegranuleringer af salte af lægemidler
AU2002220248A1 (en) * 2000-11-06 2002-05-15 Andrx Pharmaceuticals, Inc. Once a day antihistamine and decongestant formulation
US20060287254A1 (en) * 2001-01-26 2006-12-21 Schering Corporation Use of substituted azetidinone compounds for the treatment of sitosterolemia
ES2290562T3 (es) * 2001-01-26 2008-02-16 Schering Corporation Combinaciones del activador del receptor activado por el proliferador de los peroxisomas (ppar) fenofibrato con el inhibidor de la absorcion de esteroles ezetimiba para indicaciones vasculares.
EP1429756B1 (en) * 2001-09-21 2006-11-22 Schering Corporation Treatment of xanthoma with azetidinone derivatives as sterol absorption inhibitors
US7053080B2 (en) * 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
US20030206978A1 (en) * 2001-11-29 2003-11-06 Bob Sherwood Agglomerated particles including an active agent coprocessed with silicified microcrystalline cellulose
PT1469833T (pt) * 2002-02-01 2021-07-13 Bend Res Inc Método para produzir dispersões de fármaco amorfo sólido seco por pulverização homogéneas utilizando aparelho de secagem por pulverização modificado
BR0307515A (pt) * 2002-02-01 2004-12-07 Pfizer Prod Inc Método para fabricar dispersões de drogas amorfas sólidas secas por aspersão homogêneas usando bicos de pressão
US6958161B2 (en) 2002-04-12 2005-10-25 F H Faulding & Co Limited Modified release coated drug preparation
US8092831B2 (en) * 2002-11-08 2012-01-10 Andrx Pharmaceuticals, Llc Antihistamine and decongestant system
US20040109889A1 (en) 2002-12-04 2004-06-10 Bunick Frank J. Surface treatment composition for soft substrates
CA2517573C (en) * 2003-03-07 2011-12-06 Schering Corporation Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia
US7459442B2 (en) * 2003-03-07 2008-12-02 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
WO2004081002A1 (en) 2003-03-07 2004-09-23 Schering Corporation Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia
US7208486B2 (en) * 2003-03-07 2007-04-24 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
CL2004001884A1 (es) 2003-08-04 2005-06-03 Pfizer Prod Inc Procedimiento de secado por pulverizacion para la formacion de dispersiones solidas amorfas de un farmaco y polimeros.
US7201920B2 (en) 2003-11-26 2007-04-10 Acura Pharmaceuticals, Inc. Methods and compositions for deterring abuse of opioid containing dosage forms
US20070036859A1 (en) * 2005-08-11 2007-02-15 Perry Ronald L Sustained release antihistamine and decongestant composition
GB0613925D0 (en) * 2006-07-13 2006-08-23 Unilever Plc Improvements relating to nanodispersions
US20100159001A1 (en) * 2008-12-19 2010-06-24 Cardinal John R Extended-Release Pharmaceutical Formulations
US20100160363A1 (en) * 2008-12-19 2010-06-24 Aaipharma Services Corp. Extended-release pharmaceutical formulations
WO2011041414A1 (en) 2009-09-30 2011-04-07 Acura Pharmaceuticals, Inc. Methods and compositions for deterring abuse
TWI461213B (zh) * 2009-11-05 2014-11-21 Fmc Corp 作為藥物賦形劑之微晶纖維素及磷酸鈣之組合物
TW201129386A (en) * 2009-11-05 2011-09-01 Fmc Corp Microcrystalline cellulose and calcium phosphate compositions useful as pharmaceutical excipients
RU2673818C2 (ru) 2012-11-30 2018-11-30 Экьюра Фармасьютикалз, Инк. Саморегулируемое высвобождение фармацевтического ингредиента
AU2015237721B2 (en) 2014-03-26 2018-04-26 Sun Pharma Advanced Research Company Ltd. Abuse deterrent immediate release coated reservoir solid dosage form
ES2942619T3 (es) 2014-06-11 2023-06-05 SpecGx LLC Composiciones secadas por aspersión con diferentes perfiles de disolución y procedimientos para su preparación
US11103581B2 (en) 2015-08-31 2021-08-31 Acura Pharmaceuticals, Inc. Methods and compositions for self-regulated release of active pharmaceutical ingredient

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE564287A (pt) * 1957-01-28
US3111513A (en) * 1960-01-13 1963-11-19 Fmc Corp Oxidation derivatives of cellulose crystallite aggregates
US3146168A (en) * 1962-04-10 1964-08-25 Fmc Corp Manufacture of pharmaceutical preparations containing cellulose crystallite aggregates
JPS5221053B2 (pt) * 1972-09-21 1977-06-08
US4427778A (en) * 1982-06-29 1984-01-24 Biochem Technology, Inc. Enzymatic preparation of particulate cellulose for tablet making
US4600579A (en) * 1983-06-07 1986-07-15 Mallinckrodt, Inc. N-acetyl-p-aminophenol compositions containing partially gelatinized starch and method for preparing same
US4605666A (en) * 1983-10-24 1986-08-12 Basf Corporation Process for preparing spray-dried powders containing a water-soluble vitamin and powders prepared thereby
US4533674A (en) * 1983-10-24 1985-08-06 Basf Wyandotte Corporation Process for preparing a sugar and starch free spray-dried vitamin C powder containing 90 percent ascorbic acid
US4744987A (en) * 1985-03-08 1988-05-17 Fmc Corporation Coprocessed microcrystalline cellulose and calcium carbonate composition and its preparation
GB8521350D0 (en) * 1985-08-28 1985-10-02 Euro Celtique Sa Analgesic composition
US4710519A (en) * 1985-09-30 1987-12-01 Basf Corporation Process for preparing spray dried acetaminophen powder and the powder prepared thereby
US4904477A (en) * 1987-07-08 1990-02-27 American Home Products Corporation Spray dried ibuprofen compositions
US4792452A (en) * 1987-07-28 1988-12-20 E. R. Squibb & Sons, Inc. Controlled release formulation
US5466469A (en) * 1988-06-28 1995-11-14 Cibus Pharmaceutical, Inc. Granular drug delivery system
SE9002017D0 (sv) * 1990-06-06 1990-06-06 Kabivitrum Ab Process for manufacture of matrices

Also Published As

Publication number Publication date
NO326912B1 (no) 2009-03-16
NZ332295A (en) 2000-03-27
EP0942715A4 (en) 2006-01-18
EP0942715A1 (en) 1999-09-22
NO984838L (no) 1998-10-19
WO1997038678A1 (en) 1997-10-23
KR20000005514A (ko) 2000-01-25
IL126496A (en) 2001-11-25
EA199800936A1 (ru) 1999-04-29
TW541180B (en) 2003-07-11
EA000853B1 (ru) 2000-06-26
US5858409A (en) 1999-01-12
ZA973031B (en) 1997-11-04
NO984838D0 (no) 1998-10-16
IL126496A0 (en) 1999-08-17
AU2671597A (en) 1997-11-07

Similar Documents

Publication Publication Date Title
BR9708721A (pt) Processo para a preparação de uma formulação granular para compressão em tabletes farmacêuticos composição granular esférica substancialmente porosa e tabletes farmacêuticos comprimidos
EE03380B1 (et) Farmatseutiline aerosoolpreparaat ja selle valmistamismeetod
HUP0001153A3 (en) Chemically modified polypeptides, process for producing thereof, pharmaceutical compositions comprising these polypeptides and their use
HUP0004383A3 (en) Pharmaceutical preparation comprising clodronate as active ingredient and silicified microcrystalline cellulose as excipient
IL129762A0 (en) Novel macromolecules methods for their preparation pharmaceutical compositions thereof and their use as anti-influenza agents
PT1041972E (pt) Comprimido para a libertacao instantanea e prolongada de uma ou mais substancias activas
BR9406566A (pt) Composição farmacêutica uso de progesterona e/ou 17 - - estradiol e processo para a fabricação de uma preparação farmacêutica
IL116674A (en) Microcrystalline cellulose-based excipient having improved compressibility, pharmaceutical compositions containing the same and methods for the preparation of said excipient and of solid dosage form thereof
AR008252A1 (es) Granulado para la preparacion de composiciones farmaccuticas de rrpida desintegracinn y rrpida disolucinn y composiciones farmaccuticas que lo contienen
IL124214A (en) Stable freeze-dried pharmaceutical formulation
AU5936400A (en) Formulations comprising dehydrated particles of pharmaceutical agents and process for preparing the same
IL174082A0 (en) Crystal modification of a n-phenyl-2-pyrimidineamine derivative, processes for its manufacture and its use for the preparation of a pharmaceutical composition
IL123986A0 (en) Antithombotic agents process for their preparation and pharmaceutical compositions comprising them
HUP9603112A2 (en) New pharmaceutical formulation and process for its production
BR9405916A (pt) Composição detergente sólida na forma de pastilhas de material detergente granular comprimido processo para a fabricação de uma composição detergente sólido e uso da composição
BR9602150A (pt) Compostos processo para sua preparação processo para a produção de uma formulação farmacêutica formulação farmacêutica e uso
GB2343117B (en) Benzimidazole pharmaceutical composition and process of preparation
IL124779A0 (en) Novel benzoylguanidine derivatives processes for preparing them and their use in the preparation of pharmaceutical compositions
EE04119B1 (et) Külmkuivatamiseks sobiv ravimkoostis ja selle valmistamise meetod
HUP0104985A3 (en) Pharmaceutical levothyroxine compositions and process for their preparation
BR9506106A (pt) Composto processo para sua preparação medicamento e composição farmacêutica
BR9506964A (pt) Produto granulado ou comprimido contendo um sistema efervecente e uma substancia farmacéutica ativa bem como um processo para a sua preparaçao
PT842927E (pt) 3-AMIDO-CROMANILSULFONIL(TIO)-UREIAS PROCESSOS PARA A SUA PREPARACAO SUA UTILIZACAO E COMPOSICOES FARMACêUTICAS QUE AS CONTEM
HUP0004223A3 (en) 4-oxo-butynic acids and pharmaceutical composition containing them as active agent
ID20967A (id) Kroman tersubstitusi sulfonamida, proses pembuatannya, penggunaannya sebagai obat, dan sediaan farmasi yang mengandung bahan tersebut

Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]
B25A Requested transfer of rights approved

Owner name: R.P. SCHERER TECHNOLOGIES, INC. (US)

Free format text: TRANSFERIDO DE: FMC CORPORATION

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08H Application fees: decision cancelled [chapter 8.8 patent gazette]