BR9706790A - Composição imunossupressora sinergística contendo um composto 2,2'-bi- 1h-pirrole - Google Patents

Composição imunossupressora sinergística contendo um composto 2,2'-bi- 1h-pirrole

Info

Publication number
BR9706790A
BR9706790A BR9706790A BR9706790A BR9706790A BR 9706790 A BR9706790 A BR 9706790A BR 9706790 A BR9706790 A BR 9706790A BR 9706790 A BR9706790 A BR 9706790A BR 9706790 A BR9706790 A BR 9706790A
Authority
BR
Brazil
Prior art keywords
composition containing
pyrrole compound
immunosuppressive composition
synergistic
synergistic immunosuppressive
Prior art date
Application number
BR9706790A
Other languages
English (en)
Inventor
Mario Ferrari
Francesco Collota
Paola Gnocchi
Maria Chiara Fornasiero
Roberto D Alessio
Anna Maria Isetta
Original Assignee
Pharmacia & Upjohn Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Spa filed Critical Pharmacia & Upjohn Spa
Publication of BR9706790A publication Critical patent/BR9706790A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245Oxadiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13Cyclosporins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/485Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BR9706790A 1996-09-20 1997-09-02 Composição imunossupressora sinergística contendo um composto 2,2'-bi- 1h-pirrole BR9706790A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9619706.6A GB9619706D0 (en) 1996-09-20 1996-09-20 Synergistic immunosuppressant composition containing a 2,2'-bi-1H-pyrrole comp und
PCT/EP1997/004884 WO1998011894A1 (en) 1996-09-20 1997-09-02 Synergistic immunosuppressant composition containing a 2,2'-bi-1h-pyrrole compound

Publications (1)

Publication Number Publication Date
BR9706790A true BR9706790A (pt) 1999-06-01

Family

ID=10800283

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9706790A BR9706790A (pt) 1996-09-20 1997-09-02 Composição imunossupressora sinergística contendo um composto 2,2'-bi- 1h-pirrole

Country Status (20)

Country Link
US (1) US6291509B1 (pt)
EP (1) EP0866701B1 (pt)
JP (1) JP2000501118A (pt)
KR (1) KR19990067692A (pt)
AR (1) AR009086A1 (pt)
AT (1) ATE211909T1 (pt)
AU (1) AU4383197A (pt)
BR (1) BR9706790A (pt)
CA (1) CA2238043A1 (pt)
DE (1) DE69709618T2 (pt)
EA (1) EA000925B1 (pt)
ES (1) ES2174288T3 (pt)
GB (1) GB9619706D0 (pt)
HU (1) HUP9901988A3 (pt)
MX (1) MX9803920A (pt)
NO (1) NO982282L (pt)
NZ (1) NZ330655A (pt)
PL (1) PL326759A1 (pt)
WO (1) WO1998011894A1 (pt)
ZA (1) ZA978187B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0867701A1 (en) 1997-03-28 1998-09-30 Interuniversitair Microelektronica Centrum Vzw Method of fabrication of an infrared radiation detector and more particularly an infrared sensitive bolometer
EP1980263A1 (en) 1999-05-10 2008-10-15 Novartis AG Combinations of immunosuppressive agents for the treatment or prevention of graft rejections
US6407244B1 (en) 2000-01-26 2002-06-18 Gemin X Biotechnologies Inc. Pyrrole-type compounds, compositions, and methods for treating cancer or viral diseases
US20040014987A1 (en) 2000-01-26 2004-01-22 Gemin X Biotechnologies Inc. Pyrrole-Type compounds, compositions, and methods for treating cancer or viral diseases
WO2003008410A2 (en) 2001-07-18 2003-01-30 Gemin X Biotechnologies Inc. Polypyrroles as agents for treating cancer, treating viral diseases and causing immunosuppression
KR100674222B1 (ko) * 2005-07-11 2007-01-24 한국생명공학연구원 세라시아 마르세센스 b-1231 kctc 0386bp로부터분리한 프로디지오신을 유효성분으로 포함한 급성이식편대숙주병의 예방 및 치료용 조성물
CN103387529B (zh) * 2013-07-30 2016-03-30 中国农业科学院烟草研究所 抗tmv的三吡咯环类化合物及其制备方法和用途
US10654801B2 (en) 2016-04-08 2020-05-19 Institute For Cancer Research Prodigiosin analogs

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9326284D0 (en) * 1993-12-23 1994-02-23 Erba Carlo Spa Pyrrolydenemethyl-derivatives and process for their preparation

Also Published As

Publication number Publication date
NO982282L (no) 1998-07-20
DE69709618D1 (de) 2002-02-21
HUP9901988A2 (hu) 1999-10-28
EA199800464A1 (ru) 1999-02-25
ATE211909T1 (de) 2002-02-15
AU4383197A (en) 1998-04-14
ZA978187B (en) 1998-03-03
PL326759A1 (en) 1998-10-26
DE69709618T2 (de) 2002-08-29
US6291509B1 (en) 2001-09-18
GB9619706D0 (en) 1996-11-06
EA000925B1 (ru) 2000-06-26
EP0866701B1 (en) 2002-01-16
NO982282D0 (no) 1998-05-19
ES2174288T3 (es) 2002-11-01
AR009086A1 (es) 2000-03-08
KR19990067692A (ko) 1999-08-25
CA2238043A1 (en) 1998-03-26
HUP9901988A3 (en) 2000-09-28
NZ330655A (en) 2000-01-28
JP2000501118A (ja) 2000-02-02
MX9803920A (es) 1998-09-30
WO1998011894A1 (en) 1998-03-26
EP0866701A1 (en) 1998-09-30

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Legal Events

Date Code Title Description
FA10 Dismissal: dismissal - article 33 of industrial property law
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]