BR9702123A - Processo para a preparação de (-)- trans-n-p-fluorobenzoilmetil-4-(p-fluorofenil)-3,4-(m etilenodióxi)fenóxi)metil)-piperidina - Google Patents
Processo para a preparação de (-)- trans-n-p-fluorobenzoilmetil-4-(p-fluorofenil)-3,4-(m etilenodióxi)fenóxi)metil)-piperidinaInfo
- Publication number
- BR9702123A BR9702123A BR9702123-7A BR9702123A BR9702123A BR 9702123 A BR9702123 A BR 9702123A BR 9702123 A BR9702123 A BR 9702123A BR 9702123 A BR9702123 A BR 9702123A
- Authority
- BR
- Brazil
- Prior art keywords
- pct
- fluorophenyl
- phenoxy
- trans
- methyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Patente de Invenção: <B>"PROCESSO PARA A PREPARAçãO DE (-)-TRANS-N-p-FLUOROBENZOILMETIL-4-(p-FLUOROFENIL)-3-[[ 3,4-(METILENODIóXI)FENó-XI]METIL]-PIPERIDINA"<D>. O processo consise na reação do acetato de (-)-trans-N-(p-fluorofenil)-3-[[3,4-(metilenodióxi)fenóxi]metil]-piperidina com 2-cloro ou 2-bromo-4'-fluoroacetofenona, e o composto que dela resulta pode ser isolado como um sal de adição de forma farmacêutica aceitável, pela reação com o ácido correspondente.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES09600481A ES2117557B1 (es) | 1996-02-29 | 1996-02-29 | Nuevo procedimiento de obtencion de (-)-trans -n-p-fluorobenzoilmetil-4-(p-fluorofenil)-3- ((3,4-(metilendioxi)fenoxi ) metil)-piperidina. |
PCT/EP1997/001007 WO1997031915A1 (en) | 1996-02-29 | 1997-02-28 | NEW PROCESS FOR PREPARING (-)-TRANS-N-p-FLUOROBENZOYLMETHYL-4-(p-FLUOROPHENYL)-3-[[3,4-(METHYLENEDIOXY)PHENOXY]METHYL]-PIPERIDINE |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9702123A true BR9702123A (pt) | 1999-12-28 |
Family
ID=8293999
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9702123-7A BR9702123A (pt) | 1996-02-29 | 1997-02-28 | Processo para a preparação de (-)- trans-n-p-fluorobenzoilmetil-4-(p-fluorofenil)-3,4-(m etilenodióxi)fenóxi)metil)-piperidina |
Country Status (17)
Country | Link |
---|---|
US (1) | US5973155A (pt) |
EP (1) | EP0823907B1 (pt) |
JP (1) | JPH11504659A (pt) |
AT (1) | ATE180481T1 (pt) |
AU (1) | AU705887B2 (pt) |
BR (1) | BR9702123A (pt) |
CA (1) | CA2217171C (pt) |
DE (1) | DE69700236T2 (pt) |
DK (1) | DK0823907T3 (pt) |
ES (1) | ES2117557B1 (pt) |
GR (1) | GR3030683T3 (pt) |
IL (1) | IL121995A (pt) |
NO (1) | NO312549B1 (pt) |
NZ (1) | NZ328932A (pt) |
TW (1) | TW416941B (pt) |
WO (1) | WO1997031915A1 (pt) |
ZA (1) | ZA971074B (pt) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK0994872T3 (da) * | 1997-06-10 | 2001-05-28 | Synthon Bv | 4-phenylpiperidin-forbindelser |
GB9808896D0 (en) * | 1998-04-25 | 1998-06-24 | Smithkline Beecham Plc | Novel compound |
CH689805A8 (fr) * | 1998-07-02 | 2000-02-29 | Smithkline Beecham Plc | Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant. |
CA2422055A1 (en) * | 2000-09-11 | 2002-03-21 | Sepracor, Inc. | Ligands for monoamine receptors and transporters, and methods of use thereof (neurotransmission) |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3426784A1 (de) * | 1984-07-20 | 1986-01-30 | Bosch Gmbh Robert | Magnetoresistiver sensor zur abgabe von elektrischen signalen |
DK231088D0 (da) * | 1988-04-28 | 1988-04-28 | Ferrosan As | Piperidinforbindelser, deres fremstilling og anvendelse |
ES2102295B1 (es) * | 1994-03-18 | 1998-04-01 | Ferrer Int | Nuevos compuestos derivados de la n-benzoilmetil-piperidina. |
GB2297550B (en) * | 1995-02-06 | 1997-04-09 | Smithkline Beecham Plc | Paroxetine hydrochloride anhydrate substantially free of bound organic solvent |
HUP9900318A3 (en) * | 1995-05-17 | 2001-09-28 | Novo Nordisk As | Process for preparing 4-aryl-piperidine derivatives |
-
1996
- 1996-02-29 ES ES09600481A patent/ES2117557B1/es not_active Expired - Fee Related
-
1997
- 1997-01-31 TW TW086101103A patent/TW416941B/zh active
- 1997-02-10 ZA ZA9701074A patent/ZA971074B/xx unknown
- 1997-02-28 AT AT97906144T patent/ATE180481T1/de not_active IP Right Cessation
- 1997-02-28 DE DE69700236T patent/DE69700236T2/de not_active Expired - Fee Related
- 1997-02-28 CA CA002217171A patent/CA2217171C/en not_active Expired - Fee Related
- 1997-02-28 DK DK97906144T patent/DK0823907T3/da active
- 1997-02-28 BR BR9702123-7A patent/BR9702123A/pt not_active Application Discontinuation
- 1997-02-28 AU AU20940/97A patent/AU705887B2/en not_active Ceased
- 1997-02-28 EP EP97906144A patent/EP0823907B1/en not_active Expired - Lifetime
- 1997-02-28 NZ NZ328932A patent/NZ328932A/en unknown
- 1997-02-28 IL IL12199597A patent/IL121995A/xx not_active IP Right Cessation
- 1997-02-28 WO PCT/EP1997/001007 patent/WO1997031915A1/en active IP Right Grant
- 1997-02-28 JP JP9530630A patent/JPH11504659A/ja not_active Ceased
- 1997-02-28 US US08/945,442 patent/US5973155A/en not_active Expired - Fee Related
- 1997-10-27 NO NO19974958A patent/NO312549B1/no unknown
-
1999
- 1999-07-05 GR GR990401765T patent/GR3030683T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
WO1997031915A1 (en) | 1997-09-04 |
DK0823907T3 (da) | 1999-11-08 |
US5973155A (en) | 1999-10-26 |
EP0823907A1 (en) | 1998-02-18 |
GR3030683T3 (en) | 1999-11-30 |
NO974958D0 (no) | 1997-10-27 |
NZ328932A (en) | 1998-04-27 |
ES2117557A1 (es) | 1998-08-01 |
TW416941B (en) | 2001-01-01 |
ATE180481T1 (de) | 1999-06-15 |
ES2117557B1 (es) | 1999-07-01 |
DE69700236D1 (de) | 1999-07-01 |
AU2094097A (en) | 1997-09-16 |
NO974958L (no) | 1997-10-27 |
CA2217171C (en) | 2001-09-11 |
CA2217171A1 (en) | 1997-09-04 |
NO312549B1 (no) | 2002-05-27 |
IL121995A (en) | 2001-01-28 |
ZA971074B (en) | 1997-11-18 |
EP0823907B1 (en) | 1999-05-26 |
IL121995A0 (en) | 1998-03-10 |
DE69700236T2 (de) | 1999-09-30 |
AU705887B2 (en) | 1999-06-03 |
JPH11504659A (ja) | 1999-04-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK0923554T3 (da) | N-Benzylpiperidin- og tetrahydropyridinderivater | |
CA2245587A1 (en) | Novel benzo-1,3-dioxolyl- and benzofuranyl substituted pyrrolidine derivatives as endothelin antagonists | |
GB9815163D0 (en) | Compounds | |
WO2001064645A3 (en) | Derivatives of quinoline as alpha-2 antagonists | |
AU2003293585A8 (en) | Intermediate cefdinir salts | |
SK1452000A3 (en) | Pyrrolidine-3-carboxylic acid derivatives and their use as endothelin antagonists | |
EG19361A (en) | A process for the preparation of piperidine compound having local anaesthetica and analgetic | |
AU4600200A (en) | Salts of 2,2-dimethyl-1,3-dioxane intermediates and process for the preparation thereof | |
BR9702123A (pt) | Processo para a preparação de (-)- trans-n-p-fluorobenzoilmetil-4-(p-fluorofenil)-3,4-(m etilenodióxi)fenóxi)metil)-piperidina | |
EP0699429A3 (en) | Method of promoting hair growth | |
WO2000046210A3 (en) | New process for preparing pesticidal intermediates | |
AU5577800A (en) | Method for producing cloned cows | |
EA200200101A1 (ru) | Получение замещенных пиперидин-4-онов | |
CA2163253A1 (en) | N-p-halobenzoylmethyl derivatives of 4-(p-fluorophenyl)-3-¬¬3,4-methylenedioxy)phenoxy|methyl|piperidine | |
BR9809809B1 (pt) | processo para a preparação de um composto (-)-trans-1-benzil-3-hidroximetil-4-(4-fluorofenil) piperidina, e, processo para a preparação de paroxetina. | |
CA2362697A1 (en) | Substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-10-ols, method for producing them and their use as medicaments | |
AU6295600A (en) | Method for preparing 2-(2-arylmorpholin-2-yl)ethanol derivatives and intermediates | |
CA2156764A1 (en) | Process for the preparation of the (-)-n-methyl-n-[4-(4-phenyl-4-acetylaminopiperidin-1-yl)-2-(3,4-dichlorophenyl)butyl]benzamine and its pharmaceutically acceptable salts | |
ITTO20000965A0 (it) | Procedimento per produrre l'acido monocarbossilico + )-trans-crisantemico. | |
CA2366820A1 (fr) | Nouveaux derives de [(2-substitue-5 -[3-thienyl]) -benzyl]-[2- ([2-isopropoxy-5-fluoro] -phenoxy) -ethyl] -amine, leur procede de preparation et leur utilisation a titre de medicaments | |
TR200001161A2 (tr) | 8-Siklopentil-6-etil-3-[ikame edilmiş]-5, 8-Dihidro-4H-1, 2, 3A, 7, 8-Pentaaza-As-Indasenlerin hazırlandığı işlem ve burada yararlı ara bağlar. | |
AU3522899A (en) | Process for preparing 4-(substituted phenyl)-3,4-dihydro-2h-naphthalen-1-ones | |
MX9701136A (es) | Nuevo procedimiento de obtencion de (-) - trans-n-p-fluoro - benzoilmetil - 4 - (p-fluorofenil) - 3 -[ [3,4 - (metilendioxi) fenoxi] metil] - piperidina. | |
AU2002217529A1 (en) | Process for preparing optically active 2,3-dihydro- benzofuran compounds | |
AU7919600A (en) | Method for producing 2-(n-boc-aminomethyl)-thiazol-4-carboxylic acid |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |