BR9608746A - Linhagem de célula produzindo compostos analgésicos para tratamento da dor - Google Patents

Linhagem de célula produzindo compostos analgésicos para tratamento da dor

Info

Publication number
BR9608746A
BR9608746A BR9608746A BR9608746A BR9608746A BR 9608746 A BR9608746 A BR 9608746A BR 9608746 A BR9608746 A BR 9608746A BR 9608746 A BR9608746 A BR 9608746A BR 9608746 A BR9608746 A BR 9608746A
Authority
BR
Brazil
Prior art keywords
cell line
pain management
line producing
analgesic compounds
producing analgesic
Prior art date
Application number
BR9608746A
Other languages
English (en)
Inventor
Joel Saydoff
Shou Wong
Original Assignee
Cytotherapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytotherapeutics Inc filed Critical Cytotherapeutics Inc
Publication of BR9608746A publication Critical patent/BR9608746A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/70—Enkephalins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Dermatology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BR9608746A 1995-06-07 1996-06-07 Linhagem de célula produzindo compostos analgésicos para tratamento da dor BR9608746A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48191795A 1995-06-07 1995-06-07
PCT/US1996/009629 WO1996040959A1 (en) 1995-06-07 1996-06-07 Cell line producing analgesic compounds for treating pain

Publications (1)

Publication Number Publication Date
BR9608746A true BR9608746A (pt) 1999-05-11

Family

ID=23913905

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9608746A BR9608746A (pt) 1995-06-07 1996-06-07 Linhagem de célula produzindo compostos analgésicos para tratamento da dor

Country Status (20)

Country Link
EP (1) EP0833935A1 (pt)
JP (1) JPH11507530A (pt)
KR (1) KR19990022414A (pt)
CN (1) CN1192246A (pt)
AR (1) AR004494A1 (pt)
AU (1) AU6263696A (pt)
BR (1) BR9608746A (pt)
CA (1) CA2223246A1 (pt)
CZ (1) CZ392497A3 (pt)
EE (1) EE9700326A (pt)
HU (1) HUP9901191A2 (pt)
IL (1) IL122415A0 (pt)
IN (1) IN181898B (pt)
IS (1) IS4628A (pt)
NO (1) NO975545L (pt)
PL (1) PL323867A1 (pt)
SK (1) SK167997A3 (pt)
TR (1) TR199701520T1 (pt)
WO (1) WO1996040959A1 (pt)
ZA (1) ZA964880B (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1034257A2 (en) * 1997-11-28 2000-09-13 Medical Research Council Yac vectors
WO2000016799A1 (en) * 1998-09-23 2000-03-30 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Methods of treating chronic pain
US6372489B1 (en) 1998-10-27 2002-04-16 Anticancer, Inc. Method and model for hair pigmentation
ATE312916T1 (de) * 1998-10-27 2005-12-15 Anticancer Inc Herstellung eines retrovirus, welches den mel- lokus von streptomyces enthält, sowie dessen expression in säugetierzellen
US6903244B1 (en) 1999-02-26 2005-06-07 University Of Utah Research Foundation Mice which are +/− or −/− for the elastin gene as models for vascular disease
AU2002952993A0 (en) 2002-11-29 2002-12-12 The Corporation Of The Trustees Of The Order Of The Sisters Of Mercy In Queensland Therapeutic and diagnostic agents
JP2007516984A (ja) 2003-12-24 2007-06-28 ザ ウォルター アンド エリザ ホール インスティテュート オブ メディカル リサーチ 治療用物質およびそのための用途
NZ551828A (en) 2004-05-12 2009-03-31 Inst Medical W & E Hall A method of cell isolating a homogenous population of mammary stem cells using specific cell surface marker proteins
DK1910535T3 (en) 2005-06-24 2016-09-26 The Walter And Eliza Hall Inst Of Medical Res Therapeutic pro-apoptotic BH-3-like molecules and method of forming and / or selecting the same
US9717775B2 (en) 2006-07-18 2017-08-01 University Of Utah Research Foundation Methods for treating pain and screening analgesic compounds
US8889173B2 (en) * 2008-04-18 2014-11-18 Warsaw Orthopedic, Inc. Alpha adrenergic receptor agonists for treatment of pain and/or inflammation
JP6681826B2 (ja) 2013-05-31 2020-04-15 ザ ユニバーシティ オブ ユタ リサーチ ファウンデイション コノトキシンペプチド、医薬組成物およびそれらの使用
EP3368551B1 (en) 2015-10-27 2023-07-12 The University Of Queensland A modified epha4 polypeptide
CN107964047B (zh) * 2017-12-18 2018-11-02 哈尔滨工业大学 基于内吗啡肽-1和神经降压素(8-13)的嵌合肽及其合成方法和应用
CN112891337A (zh) * 2021-03-26 2021-06-04 河北医科大学 高良姜素及其衍生物在制备预防和治疗神经系统疾病药物中的用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1179350A3 (en) * 1993-08-12 2003-01-02 Cytotherapeutics, Inc. Encapsulated cell system for implantation into the human CNS

Also Published As

Publication number Publication date
IN181898B (pt) 1998-10-24
CZ392497A3 (cs) 1998-12-16
JPH11507530A (ja) 1999-07-06
AU6263696A (en) 1996-12-30
IL122415A0 (en) 1998-06-15
HUP9901191A2 (hu) 1999-08-30
AR004494A1 (es) 1998-12-16
CN1192246A (zh) 1998-09-02
EP0833935A1 (en) 1998-04-08
CA2223246A1 (en) 1996-12-19
IS4628A (is) 1997-12-04
ZA964880B (en) 1997-01-07
WO1996040959A1 (en) 1996-12-19
NO975545D0 (no) 1997-12-02
SK167997A3 (en) 1998-05-06
KR19990022414A (ko) 1999-03-25
EE9700326A (et) 1998-06-15
TR199701520T1 (xx) 1998-04-21
NO975545L (no) 1998-02-04
PL323867A1 (en) 1998-04-27

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Legal Events

Date Code Title Description
FD5 Application fees: dismissal - article 86 of industrial property law