BR9607673A - Processo para estimular a meiose de uma célula germinativa e uso de um composto que causa o acúmulo de uma substância endógena ativadora de meiose - Google Patents
Processo para estimular a meiose de uma célula germinativa e uso de um composto que causa o acúmulo de uma substância endógena ativadora de meioseInfo
- Publication number
- BR9607673A BR9607673A BR9607673A BR9607673A BR9607673A BR 9607673 A BR9607673 A BR 9607673A BR 9607673 A BR9607673 A BR 9607673A BR 9607673 A BR9607673 A BR 9607673A BR 9607673 A BR9607673 A BR 9607673A
- Authority
- BR
- Brazil
- Prior art keywords
- meiosis
- accumulation
- compound
- causes
- germ cell
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0608—Germ cells
- C12N5/0609—Oocytes, oogonia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0608—Germ cells
- C12N5/061—Sperm cells, spermatogonia
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Reproductive Health (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK23295 | 1995-03-06 | ||
| DK30995 | 1995-03-24 | ||
| PCT/DK1996/000093 WO1996027658A1 (en) | 1995-03-06 | 1996-03-06 | Stimulation of meiosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9607673A true BR9607673A (pt) | 1998-06-16 |
Family
ID=26063579
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9607673A BR9607673A (pt) | 1995-03-06 | 1996-03-06 | Processo para estimular a meiose de uma célula germinativa e uso de um composto que causa o acúmulo de uma substância endógena ativadora de meiose |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5830757A (pt) |
| EP (1) | EP0813595A1 (pt) |
| JP (1) | JPH11501806A (pt) |
| KR (1) | KR19980702624A (pt) |
| AU (1) | AU717180B2 (pt) |
| BR (1) | BR9607673A (pt) |
| CA (1) | CA2214126A1 (pt) |
| CZ (1) | CZ279797A3 (pt) |
| HU (1) | HUP9800731A3 (pt) |
| NO (1) | NO974089L (pt) |
| PL (1) | PL322106A1 (pt) |
| RU (1) | RU2188006C2 (pt) |
| WO (1) | WO1996027658A1 (pt) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0946584B1 (en) | 1996-12-20 | 2003-04-23 | Novo Nordisk A/S | Meiosis regulating compounds |
| ES2189173T3 (es) * | 1997-05-16 | 2003-07-01 | Akzo Nobel Nv | Derivados de 20-aril-5alfa-pregnano. |
| ATE215555T1 (de) | 1997-06-04 | 2002-04-15 | Akzo Nobel Nv | 17-beta.-allyloxy(thio)alkyl-androstan derivative zur modulation von meiose |
| US6251887B1 (en) | 1997-12-18 | 2001-06-26 | Akzo Nobel N.V. | 17β-aryl(arylmethyl)oxy(thio)alkyl-androstane derivatives |
| EP0957108A1 (en) * | 1998-05-14 | 1999-11-17 | Schering Aktiengesellschaft | Unsaturated cholestane derivatives, pharmaceutical compositions comprising them and use of these derivatives for the preparation of meiosis regulating medicaments |
| IL139241A0 (en) | 1998-05-13 | 2001-11-25 | Novo Nordisk As | Meiosis regulating compounds |
| EP1098652A2 (en) * | 1998-05-26 | 2001-05-16 | Schering Aktiengesellschaft | Treatment of infertility with camp-increasing compounds alone or in combination with at least one meiosis-stimulating compound |
| WO1999067273A1 (en) * | 1998-06-19 | 1999-12-29 | Novo Nordisk A/S | Meiosis regulating compounds |
| ES2185360T3 (es) | 1998-12-11 | 2003-04-16 | Akzo Nobel Nv | Derivados de 22s-hidroxicolesta-8,14-dieno con actividad reguladora de la meiosis. |
| AU3279700A (en) * | 1999-02-10 | 2000-08-29 | Schering Aktiengesellschaft | Unsaturated cholestane derivatives and their use for the preparation of meiosis regulating medicaments |
| ATE317266T1 (de) * | 1999-02-24 | 2006-02-15 | Novo Nordisk As | In vitro methode zur synchronisation von oozytenreifung |
| ATE361091T1 (de) * | 1999-02-24 | 2007-05-15 | Novo Nordisk As | Behandlung von unfruchtbarkeit |
| CZ20012671A3 (cs) * | 1999-02-26 | 2002-01-16 | Novo Nordisk A/S | Způsob in vitro oplodnění s pouľitím kultivačního média obsahujícího sterol aktivující meiosu |
| ATE229538T1 (de) * | 1999-03-09 | 2002-12-15 | Akzo Nobel Nv | 22r-hydroxycholesta-8,14-diene derivate zur hemmung der meiose |
| EA200101157A1 (ru) * | 1999-05-10 | 2002-06-27 | Шеринг Акциенгезельшафт | 14β-H-СТЕРОЛЫ, СОДЕРЖАЩИЕ ИХ ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ И ПРИМЕНЕНИЕ ЭТИХ ПРОИЗВОДНЫХ ДЛЯ ПРИГОТОВЛЕНИЯ ЛЕКАРСТВЕННЫХ СРЕДСТВ, РЕГУЛИРУЮЩИХ МЕЙОЗ |
| IL148234A0 (en) | 1999-09-16 | 2002-09-12 | Novo Nordisk As | Composition for ivf |
| EP1127890A1 (en) | 2000-02-22 | 2001-08-29 | Schering Aktiengesellschaft | Steroid derivatives with an additional ring annulated to ring A and use of these derivatives for the preparation of meiosis regulating medicaments |
| WO2001088098A2 (en) * | 2000-05-18 | 2001-11-22 | Schering Aktiengesellschaft | Fertilization of aged oocytes |
| EP1216701A1 (en) * | 2000-12-22 | 2002-06-26 | Schering Aktiengesellschaft | Process to increase the concentration of meiosis-activating sterols (MAS) in the cholesterol synthesis and the use of potent inhibitors in the process |
| EP1245572A1 (en) | 2001-03-26 | 2002-10-02 | Schering Aktiengesellschaft | Aminosterol compounds, their use in the preparation of meiosis-regulating medicaments and method for their preparation |
| US20050020666A1 (en) * | 2003-07-25 | 2005-01-27 | Dabur Research Foundation | Cardioprotective agents |
| US20090105333A1 (en) * | 2006-05-22 | 2009-04-23 | Gunther Birznieks | Melatonin agonist treatment |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5716777A (en) * | 1994-06-23 | 1998-02-10 | Novo Nordisk A/S | Regulation of meiosis using sterols |
-
1996
- 1996-03-06 RU RU97116491/14A patent/RU2188006C2/ru not_active IP Right Cessation
- 1996-03-06 AU AU47845/96A patent/AU717180B2/en not_active Ceased
- 1996-03-06 JP JP8526543A patent/JPH11501806A/ja active Pending
- 1996-03-06 PL PL96322106A patent/PL322106A1/xx unknown
- 1996-03-06 HU HU9800731A patent/HUP9800731A3/hu unknown
- 1996-03-06 WO PCT/DK1996/000093 patent/WO1996027658A1/en not_active Application Discontinuation
- 1996-03-06 BR BR9607673A patent/BR9607673A/pt not_active Application Discontinuation
- 1996-03-06 CZ CZ972797A patent/CZ279797A3/cs unknown
- 1996-03-06 EP EP96903940A patent/EP0813595A1/en not_active Withdrawn
- 1996-03-06 CA CA002214126A patent/CA2214126A1/en not_active Abandoned
- 1996-03-06 KR KR1019970706029A patent/KR19980702624A/ko not_active Application Discontinuation
-
1997
- 1997-02-28 US US08/807,928 patent/US5830757A/en not_active Expired - Fee Related
- 1997-09-05 NO NO974089A patent/NO974089L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| HUP9800731A2 (hu) | 1998-07-28 |
| AU717180B2 (en) | 2000-03-16 |
| RU2188006C2 (ru) | 2002-08-27 |
| KR19980702624A (ko) | 1998-08-05 |
| US5830757A (en) | 1998-11-03 |
| CA2214126A1 (en) | 1996-09-12 |
| CZ279797A3 (cs) | 1998-01-14 |
| EP0813595A1 (en) | 1997-12-29 |
| AU4784596A (en) | 1996-09-23 |
| HUP9800731A3 (en) | 2000-03-28 |
| PL322106A1 (en) | 1998-01-05 |
| NO974089D0 (no) | 1997-09-05 |
| MX9706565A (es) | 1997-11-29 |
| JPH11501806A (ja) | 1999-02-16 |
| WO1996027658A1 (en) | 1996-09-12 |
| NO974089L (no) | 1997-09-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B15K | Others concerning applications: alteration of classification |
Ipc: A61K 31/7048 (2006.01), A61K 31/00 (2006.0 |