ATE215555T1 - 17-beta.-allyloxy(thio)alkyl-androstan derivative zur modulation von meiose - Google Patents

17-beta.-allyloxy(thio)alkyl-androstan derivative zur modulation von meiose

Info

Publication number
ATE215555T1
ATE215555T1 AT98936293T AT98936293T ATE215555T1 AT E215555 T1 ATE215555 T1 AT E215555T1 AT 98936293 T AT98936293 T AT 98936293T AT 98936293 T AT98936293 T AT 98936293T AT E215555 T1 ATE215555 T1 AT E215555T1
Authority
AT
Austria
Prior art keywords
alkyl
independently hydrogen
allyloxy
thio
meiosis
Prior art date
Application number
AT98936293T
Other languages
English (en)
Inventor
Johannes Antonius Jos Leemhuis
Der Louw Jaap Van
Marinus Bernard Groen
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Application granted granted Critical
Publication of ATE215555T1 publication Critical patent/ATE215555T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J51/00Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/0065Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified
    • C07J7/007Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified not substituted in position 17 alfa

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT98936293T 1997-06-04 1998-05-28 17-beta.-allyloxy(thio)alkyl-androstan derivative zur modulation von meiose ATE215555T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97201691 1997-06-04
PCT/EP1998/003191 WO1998055498A1 (en) 1997-06-04 1998-05-28 17β-ALLYLOXY(THIO)ALKYL-ANDROSTANE DERIVATIVES FOR THE MODULATION OF MEIOSIS

Publications (1)

Publication Number Publication Date
ATE215555T1 true ATE215555T1 (de) 2002-04-15

Family

ID=8228406

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98936293T ATE215555T1 (de) 1997-06-04 1998-05-28 17-beta.-allyloxy(thio)alkyl-androstan derivative zur modulation von meiose

Country Status (16)

Country Link
US (1) US6262282B1 (de)
EP (1) EP0988312B1 (de)
JP (1) JP2002502404A (de)
KR (1) KR20010013401A (de)
CN (1) CN1259138A (de)
AT (1) ATE215555T1 (de)
AU (1) AU8535398A (de)
CA (1) CA2289524A1 (de)
DE (1) DE69804611T2 (de)
DK (1) DK0988312T3 (de)
HU (1) HUP0002904A2 (de)
IL (1) IL132799A0 (de)
NO (1) NO995935L (de)
PL (1) PL337188A1 (de)
TR (1) TR199902873T2 (de)
WO (1) WO1998055498A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1042353B1 (de) 1997-12-18 2002-07-17 Akzo Nobel N.V. 17beta-aryl(arylmethyl)oxy(thio)alkyl-androstanderivative
EP1077992B1 (de) * 1998-05-13 2003-12-10 Novo Nordisk A/S Verwendung von verbindungen mit der fähigkeit die meiose zu regulieren
AU4498299A (en) * 1998-06-19 2000-01-10 Novo Nordisk A/S Meiosis regulating compounds
ATE361091T1 (de) * 1999-02-24 2007-05-15 Novo Nordisk As Behandlung von unfruchtbarkeit
JP2002537349A (ja) * 1999-02-24 2002-11-05 ノボ ノルディスク アクティーゼルスカブ 不妊症の治療
EP1162977B1 (de) * 1999-03-02 2008-04-23 N.V. Organon (androst-5-en-17beta-yl)alkyl sulfoxide und sulfone und deren verwendung zur kontrolle der fruchtbarkeit
DE60004377T2 (de) * 1999-04-06 2004-06-09 Akzo Nobel N.V. Oral wirksame 7-alpha-alkyl androgene
WO2001019354A2 (en) 1999-09-16 2001-03-22 Novo Nordisk A/S Composition for ivf
EP1127890A1 (de) 2000-02-22 2001-08-29 Schering Aktiengesellschaft Steroid Derivate mit einem an Ring A des Steroidgerüstes kondensierten Ring zur Regulierung der Meiose
WO2001062260A2 (en) * 2000-02-25 2001-08-30 Schering Aktiengesellschaft Improvement of implantation rate
MXPA02011271A (es) * 2000-05-18 2003-04-25 Schering Ag Fertilizacion de oocitos envejecidos.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5716777A (en) * 1994-06-23 1998-02-10 Novo Nordisk A/S Regulation of meiosis using sterols
BR9607673A (pt) 1995-03-06 1998-06-16 Novo Nordisk As Processo para estimular a meiose de uma célula germinativa e uso de um composto que causa o acúmulo de uma substância endógena ativadora de meiose
DE69630802T2 (de) 1995-06-23 2004-08-12 Novo Nordisk A/S Meiose regulierende verbindungen.

Also Published As

Publication number Publication date
AU8535398A (en) 1998-12-21
CN1259138A (zh) 2000-07-05
KR20010013401A (ko) 2001-02-26
HUP0002904A2 (hu) 2001-02-28
DE69804611T2 (de) 2002-10-02
NO995935L (no) 2000-02-03
PL337188A1 (en) 2000-08-14
EP0988312A1 (de) 2000-03-29
TR199902873T2 (xx) 2000-04-21
IL132799A0 (en) 2001-03-19
EP0988312B1 (de) 2002-04-03
NO995935D0 (no) 1999-12-03
DK0988312T3 (da) 2002-07-15
DE69804611D1 (de) 2002-05-08
CA2289524A1 (en) 1998-12-10
WO1998055498A1 (en) 1998-12-10
US6262282B1 (en) 2001-07-17
JP2002502404A (ja) 2002-01-22

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties