ATE215555T1 - 17-beta.-allyloxy(thio)alkyl-androstan derivative zur modulation von meiose - Google Patents
17-beta.-allyloxy(thio)alkyl-androstan derivative zur modulation von meioseInfo
- Publication number
- ATE215555T1 ATE215555T1 AT98936293T AT98936293T ATE215555T1 AT E215555 T1 ATE215555 T1 AT E215555T1 AT 98936293 T AT98936293 T AT 98936293T AT 98936293 T AT98936293 T AT 98936293T AT E215555 T1 ATE215555 T1 AT E215555T1
- Authority
- AT
- Austria
- Prior art keywords
- alkyl
- independently hydrogen
- allyloxy
- thio
- meiosis
- Prior art date
Links
- 230000021121 meiosis Effects 0.000 title abstract 2
- SCVJRXQHFJXZFZ-KVQBGUIXSA-N 2-amino-9-[(2r,4s,5r)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3h-purine-6-thione Chemical class C1=2NC(N)=NC(=S)C=2N=CN1[C@H]1C[C@H](O)[C@@H](CO)O1 SCVJRXQHFJXZFZ-KVQBGUIXSA-N 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
- 229910020008 S(O) Inorganic materials 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- 229910004727 OSO3H Inorganic materials 0.000 abstract 1
- 230000003213 activating effect Effects 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 150000001721 carbon Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000392 cycloalkenyl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 230000035558 fertility Effects 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
- C07J7/0065—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified
- C07J7/007—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified not substituted in position 17 alfa
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97201691 | 1997-06-04 | ||
| PCT/EP1998/003191 WO1998055498A1 (en) | 1997-06-04 | 1998-05-28 | 17β-ALLYLOXY(THIO)ALKYL-ANDROSTANE DERIVATIVES FOR THE MODULATION OF MEIOSIS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE215555T1 true ATE215555T1 (de) | 2002-04-15 |
Family
ID=8228406
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98936293T ATE215555T1 (de) | 1997-06-04 | 1998-05-28 | 17-beta.-allyloxy(thio)alkyl-androstan derivative zur modulation von meiose |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6262282B1 (de) |
| EP (1) | EP0988312B1 (de) |
| JP (1) | JP2002502404A (de) |
| KR (1) | KR20010013401A (de) |
| CN (1) | CN1259138A (de) |
| AT (1) | ATE215555T1 (de) |
| AU (1) | AU8535398A (de) |
| CA (1) | CA2289524A1 (de) |
| DE (1) | DE69804611T2 (de) |
| DK (1) | DK0988312T3 (de) |
| HU (1) | HUP0002904A2 (de) |
| IL (1) | IL132799A0 (de) |
| NO (1) | NO995935L (de) |
| PL (1) | PL337188A1 (de) |
| TR (1) | TR199902873T2 (de) |
| WO (1) | WO1998055498A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1042353B1 (de) * | 1997-12-18 | 2002-07-17 | Akzo Nobel N.V. | 17beta-aryl(arylmethyl)oxy(thio)alkyl-androstanderivative |
| DE69913513T2 (de) * | 1998-05-13 | 2004-09-30 | Novo Nordisk A/S | Verwendung von verbindungen mit der fähigkeit die meiose zu regulieren |
| AU4498299A (en) * | 1998-06-19 | 2000-01-10 | Novo Nordisk A/S | Meiosis regulating compounds |
| CA2363074A1 (en) | 1999-02-24 | 2000-08-31 | Novo Nordisk A/S | Treatment of infertility |
| ES2258445T3 (es) * | 1999-02-24 | 2006-09-01 | Novo Nordisk A/S | Metodo in vitro para la sincronizacion de la maduracion de ovocitos. |
| AU2914800A (en) * | 1999-03-02 | 2000-09-21 | Akzo Nobel N.V. | (androst-5-en-17beta-yl)alkyl sulfoxides and sulfones and their use for control of fertility |
| ES2204613T3 (es) * | 1999-04-06 | 2004-05-01 | Akzo Nobel N.V. | Androgenos 7-alfa alquilo oralmente activos. |
| ATE306942T1 (de) | 1999-09-16 | 2005-11-15 | Novo Nordisk As | Zusammensetzung zur in-vitro befruchtung |
| EP1127890A1 (de) | 2000-02-22 | 2001-08-29 | Schering Aktiengesellschaft | Steroid Derivate mit einem an Ring A des Steroidgerüstes kondensierten Ring zur Regulierung der Meiose |
| WO2001062260A2 (en) * | 2000-02-25 | 2001-08-30 | Schering Aktiengesellschaft | Improvement of implantation rate |
| MXPA02011271A (es) * | 2000-05-18 | 2003-04-25 | Schering Ag | Fertilizacion de oocitos envejecidos. |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5716777A (en) * | 1994-06-23 | 1998-02-10 | Novo Nordisk A/S | Regulation of meiosis using sterols |
| JPH11501806A (ja) | 1995-03-06 | 1999-02-16 | ノボ ノルディスク アクティーゼルスカブ | 減数分裂の刺激 |
| RU2182909C2 (ru) | 1995-06-23 | 2002-05-27 | Ново Нордиск А/С | Стероиды, способ регулирования мейоза |
-
1998
- 1998-05-28 CN CN98805807A patent/CN1259138A/zh active Pending
- 1998-05-28 HU HU0002904A patent/HUP0002904A2/hu unknown
- 1998-05-28 WO PCT/EP1998/003191 patent/WO1998055498A1/en not_active Ceased
- 1998-05-28 US US09/445,202 patent/US6262282B1/en not_active Expired - Fee Related
- 1998-05-28 TR TR1999/02873T patent/TR199902873T2/xx unknown
- 1998-05-28 EP EP98936293A patent/EP0988312B1/de not_active Expired - Lifetime
- 1998-05-28 DE DE69804611T patent/DE69804611T2/de not_active Expired - Fee Related
- 1998-05-28 JP JP50144599A patent/JP2002502404A/ja not_active Ceased
- 1998-05-28 KR KR19997011402A patent/KR20010013401A/ko not_active Withdrawn
- 1998-05-28 CA CA002289524A patent/CA2289524A1/en not_active Abandoned
- 1998-05-28 DK DK98936293T patent/DK0988312T3/da active
- 1998-05-28 IL IL13279998A patent/IL132799A0/xx unknown
- 1998-05-28 AT AT98936293T patent/ATE215555T1/de not_active IP Right Cessation
- 1998-05-28 PL PL98337188A patent/PL337188A1/xx unknown
- 1998-05-28 AU AU85353/98A patent/AU8535398A/en not_active Abandoned
-
1999
- 1999-12-03 NO NO995935A patent/NO995935L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US6262282B1 (en) | 2001-07-17 |
| JP2002502404A (ja) | 2002-01-22 |
| DE69804611D1 (de) | 2002-05-08 |
| CN1259138A (zh) | 2000-07-05 |
| CA2289524A1 (en) | 1998-12-10 |
| AU8535398A (en) | 1998-12-21 |
| NO995935D0 (no) | 1999-12-03 |
| DK0988312T3 (da) | 2002-07-15 |
| NO995935L (no) | 2000-02-03 |
| KR20010013401A (ko) | 2001-02-26 |
| EP0988312B1 (de) | 2002-04-03 |
| EP0988312A1 (de) | 2000-03-29 |
| WO1998055498A1 (en) | 1998-12-10 |
| TR199902873T2 (xx) | 2000-04-21 |
| PL337188A1 (en) | 2000-08-14 |
| HUP0002904A2 (hu) | 2001-02-28 |
| IL132799A0 (en) | 2001-03-19 |
| DE69804611T2 (de) | 2002-10-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK0870768T3 (da) | Azaindol-ethylaminderivater som nikotinacetylcholinreceptor-bindingsmidler | |
| ATE103812T1 (de) | Zusammensetzung zur behandlung von ischaemischen stoerungen in organen. | |
| ATE263771T1 (de) | Totalsynthese von acylfulvenen mit antitumorwirkung | |
| ATE215555T1 (de) | 17-beta.-allyloxy(thio)alkyl-androstan derivative zur modulation von meiose | |
| RU95105435A (ru) | N-замещенные производные 3-азабицикло [3.2.0]гептана в качестве нейролептического средства | |
| EP1004573A4 (de) | Aryloxyanilin-derivate | |
| NO995590D0 (no) | 20-Aryl-5<alfa>-pregnan-derivater | |
| TR199902350T2 (xx) | Yeni piridin t�revleri ve onlardan olu�an farmakotik bile�imler. | |
| DK0882728T3 (da) | 1-methylcarbapenemderivater | |
| DE69828197D1 (de) | Amidderivate zur behandlung neurodegenerativer erkrankungen der netzhaut | |
| ATE356816T1 (de) | Trizyklische keto amid derivative als farnesyl protein transferase inhibitoren | |
| DE59304311D1 (de) | N-substituierte 3-azabicyclo[3.2.0]heptan-derivate als neuroleptika | |
| DE60000978D1 (de) | 22r-hydroxycholesta-8,14-diene derivate zur hemmung der meiose | |
| DE69001004D1 (de) | Zusammensetzung gegen leberkrankheiten. | |
| DK1042353T3 (da) | 17-beta-aryl(arylmethyl)oxy(thio)alkylandrostanderivater | |
| ES2149180T3 (es) | Derivado de pirazolotiazolopirimidina. | |
| ATE140919T1 (de) | Indolderivate | |
| DE69903346D1 (de) | 22s-hydroxycholesta-8,14-dien derivate mit meiose regulierende aktivität |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |