ATE215555T1 - 17-beta.-allyloxy(thio)alkyl-androstan derivative zur modulation von meiose - Google Patents
17-beta.-allyloxy(thio)alkyl-androstan derivative zur modulation von meioseInfo
- Publication number
- ATE215555T1 ATE215555T1 AT98936293T AT98936293T ATE215555T1 AT E215555 T1 ATE215555 T1 AT E215555T1 AT 98936293 T AT98936293 T AT 98936293T AT 98936293 T AT98936293 T AT 98936293T AT E215555 T1 ATE215555 T1 AT E215555T1
- Authority
- AT
- Austria
- Prior art keywords
- alkyl
- independently hydrogen
- allyloxy
- thio
- meiosis
- Prior art date
Links
- 230000021121 meiosis Effects 0.000 title abstract 2
- SCVJRXQHFJXZFZ-KVQBGUIXSA-N 2-amino-9-[(2r,4s,5r)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3h-purine-6-thione Chemical class C1=2NC(N)=NC(=S)C=2N=CN1[C@H]1C[C@H](O)[C@@H](CO)O1 SCVJRXQHFJXZFZ-KVQBGUIXSA-N 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
- 229910020008 S(O) Inorganic materials 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- 229910004727 OSO3H Inorganic materials 0.000 abstract 1
- 230000003213 activating effect Effects 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 150000001721 carbon Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000392 cycloalkenyl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 230000035558 fertility Effects 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
- C07J7/0065—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified
- C07J7/007—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified not substituted in position 17 alfa
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97201691 | 1997-06-04 | ||
| PCT/EP1998/003191 WO1998055498A1 (en) | 1997-06-04 | 1998-05-28 | 17β-ALLYLOXY(THIO)ALKYL-ANDROSTANE DERIVATIVES FOR THE MODULATION OF MEIOSIS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE215555T1 true ATE215555T1 (de) | 2002-04-15 |
Family
ID=8228406
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98936293T ATE215555T1 (de) | 1997-06-04 | 1998-05-28 | 17-beta.-allyloxy(thio)alkyl-androstan derivative zur modulation von meiose |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6262282B1 (de) |
| EP (1) | EP0988312B1 (de) |
| JP (1) | JP2002502404A (de) |
| KR (1) | KR20010013401A (de) |
| CN (1) | CN1259138A (de) |
| AT (1) | ATE215555T1 (de) |
| AU (1) | AU8535398A (de) |
| CA (1) | CA2289524A1 (de) |
| DE (1) | DE69804611T2 (de) |
| DK (1) | DK0988312T3 (de) |
| HU (1) | HUP0002904A2 (de) |
| IL (1) | IL132799A0 (de) |
| NO (1) | NO995935L (de) |
| PL (1) | PL337188A1 (de) |
| TR (1) | TR199902873T2 (de) |
| WO (1) | WO1998055498A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2181321T3 (es) * | 1997-12-18 | 2003-02-16 | Akzo Nobel Nv | Derivados 17beta-aril(arilmetil)oxi(tio)alquilandrostano. |
| DE69913513T2 (de) * | 1998-05-13 | 2004-09-30 | Novo Nordisk A/S | Verwendung von verbindungen mit der fähigkeit die meiose zu regulieren |
| AU4498299A (en) * | 1998-06-19 | 2000-01-10 | Novo Nordisk A/S | Meiosis regulating compounds |
| CN1353617A (zh) * | 1999-02-24 | 2002-06-12 | 诺沃挪第克公司 | 不孕症的治疗 |
| EP1156821B1 (de) * | 1999-02-24 | 2007-05-02 | Novo Nordisk A/S | Behandlung von unfruchtbarkeit |
| JP2002538123A (ja) * | 1999-03-02 | 2002-11-12 | アクゾ・ノベル・エヌ・ベー | （アンドロスト−５−エン−１７β−イル）アルキルスルホキシドおよびスルホンならびに受胎能の調節のためのその使用 |
| US6756366B1 (en) * | 1999-04-06 | 2004-06-29 | Akzo Nobel N.V. | Orally active androgens |
| DE60023324T2 (de) | 1999-09-16 | 2006-07-20 | Novo Nordisk A/S | Zusammensetzung zur in-vitro befruchtung |
| EP1127890A1 (de) | 2000-02-22 | 2001-08-29 | Schering Aktiengesellschaft | Steroid Derivate mit einem an Ring A des Steroidgerüstes kondensierten Ring zur Regulierung der Meiose |
| AU3376501A (en) * | 2000-02-25 | 2001-09-03 | Novo Nordisk A/S | Improvement of implantation rate |
| CA2404822A1 (en) * | 2000-05-18 | 2001-11-22 | Novo Nordisk A/S | Fertilization of aged oocytes |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5716777A (en) * | 1994-06-23 | 1998-02-10 | Novo Nordisk A/S | Regulation of meiosis using sterols |
| PL322106A1 (en) * | 1995-03-06 | 1998-01-05 | Novo Nordisk As | Meiosis stimulation |
| PL185622B1 (pl) * | 1995-06-23 | 2003-06-30 | Novo Nordisk As | Zastosowanie związku steroidowego i sposób regulacji mejozy w komórce rozrodczej ssaka |
-
1998
- 1998-05-28 AU AU85353/98A patent/AU8535398A/en not_active Abandoned
- 1998-05-28 CN CN98805807A patent/CN1259138A/zh active Pending
- 1998-05-28 DE DE69804611T patent/DE69804611T2/de not_active Expired - Fee Related
- 1998-05-28 PL PL98337188A patent/PL337188A1/xx unknown
- 1998-05-28 KR KR19997011402A patent/KR20010013401A/ko not_active Withdrawn
- 1998-05-28 IL IL13279998A patent/IL132799A0/xx unknown
- 1998-05-28 CA CA002289524A patent/CA2289524A1/en not_active Abandoned
- 1998-05-28 US US09/445,202 patent/US6262282B1/en not_active Expired - Fee Related
- 1998-05-28 EP EP98936293A patent/EP0988312B1/de not_active Expired - Lifetime
- 1998-05-28 JP JP50144599A patent/JP2002502404A/ja not_active Ceased
- 1998-05-28 WO PCT/EP1998/003191 patent/WO1998055498A1/en not_active Ceased
- 1998-05-28 TR TR1999/02873T patent/TR199902873T2/xx unknown
- 1998-05-28 DK DK98936293T patent/DK0988312T3/da active
- 1998-05-28 HU HU0002904A patent/HUP0002904A2/hu unknown
- 1998-05-28 AT AT98936293T patent/ATE215555T1/de not_active IP Right Cessation
-
1999
- 1999-12-03 NO NO995935A patent/NO995935L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1259138A (zh) | 2000-07-05 |
| DE69804611D1 (de) | 2002-05-08 |
| HUP0002904A2 (hu) | 2001-02-28 |
| DK0988312T3 (da) | 2002-07-15 |
| JP2002502404A (ja) | 2002-01-22 |
| CA2289524A1 (en) | 1998-12-10 |
| NO995935D0 (no) | 1999-12-03 |
| EP0988312B1 (de) | 2002-04-03 |
| IL132799A0 (en) | 2001-03-19 |
| WO1998055498A1 (en) | 1998-12-10 |
| EP0988312A1 (de) | 2000-03-29 |
| TR199902873T2 (xx) | 2000-04-21 |
| DE69804611T2 (de) | 2002-10-02 |
| KR20010013401A (ko) | 2001-02-26 |
| US6262282B1 (en) | 2001-07-17 |
| AU8535398A (en) | 1998-12-21 |
| PL337188A1 (en) | 2000-08-14 |
| NO995935L (no) | 2000-02-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |