BR9509087A - Process for the quantitative synthesis of 3- (1-pyroglutamyl) -1-thiazolidine-4-carboxylic acid and derivatives thereof - Google Patents

Process for the quantitative synthesis of 3- (1-pyroglutamyl) -1-thiazolidine-4-carboxylic acid and derivatives thereof

Info

Publication number
BR9509087A
BR9509087A BR9509087A BR9509087A BR9509087A BR 9509087 A BR9509087 A BR 9509087A BR 9509087 A BR9509087 A BR 9509087A BR 9509087 A BR9509087 A BR 9509087A BR 9509087 A BR9509087 A BR 9509087A
Authority
BR
Brazil
Prior art keywords
pyroglutamyl
thiazolidine
derivatives
carboxylic acid
quantitative synthesis
Prior art date
Application number
BR9509087A
Other languages
Portuguese (pt)
Inventor
Ambrogio Magni
Stefano Poli
Gianettore Bocchiola
Original Assignee
Poli Ind S P A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Poli Ind S P A filed Critical Poli Ind S P A
Publication of BR9509087A publication Critical patent/BR9509087A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06173—Dipeptides with the first amino acid being heterocyclic and Glp-amino acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Pyrrole Compounds (AREA)
BR9509087A 1994-09-27 1995-09-21 Process for the quantitative synthesis of 3- (1-pyroglutamyl) -1-thiazolidine-4-carboxylic acid and derivatives thereof BR9509087A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI941955A IT1270017B (en) 1994-09-27 1994-09-27 "QUANTITATIVE SYNTHESIS OF 3- (L-PIROGLUTAMIL) -L-THIAZOLIDIN-4- CARBOXYLIC ACID AND ITS DERIVATIVES"
PCT/EP1995/003720 WO1996010036A1 (en) 1994-09-27 1995-09-21 A process for the quantitative synthesis of 3-(l-pyroglutamyl)-l-thiazolidine-4-carboxylic acid and derivatives thereof

Publications (1)

Publication Number Publication Date
BR9509087A true BR9509087A (en) 1998-07-21

Family

ID=11369599

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9509087A BR9509087A (en) 1994-09-27 1995-09-21 Process for the quantitative synthesis of 3- (1-pyroglutamyl) -1-thiazolidine-4-carboxylic acid and derivatives thereof

Country Status (10)

Country Link
CN (1) CN1143863C (en)
BG (1) BG63895B1 (en)
BR (1) BR9509087A (en)
CO (1) CO4480030A1 (en)
CZ (1) CZ91597A3 (en)
IT (1) IT1270017B (en)
PL (1) PL181824B1 (en)
RO (1) RO115957B1 (en)
SK (1) SK40097A3 (en)
WO (1) WO1996010036A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108088936B (en) * 2017-12-08 2020-05-22 常州寅盛药业有限公司 Impurity obtained in preparation of pidotimod ethyl ester and quality detection method thereof
CN108715598A (en) * 2018-06-13 2018-10-30 峨眉山宏昇药业股份有限公司 A kind of preparation method of Pidotimod
CN117088939A (en) * 2022-05-11 2023-11-21 江苏吴中医药集团有限公司 Preparation method of pidotimod

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1202426B (en) * 1987-01-26 1989-02-09 Poli Ind Chimica Spa THIAZOLIDIN-4-CARBOXYLIC ACID DERIVATIVE, ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN IT
IT1239029B (en) * 1989-10-12 1993-09-20 Poli Ind Chimica Spa PROCESS FOR THE PREPARATION OF 3- (L-PYROGLUTAMYL) -L- THIAZOLIDIN-4-CARBOXYLIC ACID AND ITS DERIVATIVES.

Also Published As

Publication number Publication date
SK40097A3 (en) 1997-09-10
BG101310A (en) 1997-12-30
CO4480030A1 (en) 1997-07-09
PL319380A1 (en) 1997-08-04
WO1996010036A1 (en) 1996-04-04
RO115957B1 (en) 2000-08-30
CZ91597A3 (en) 1997-09-17
ITMI941955A1 (en) 1996-03-27
CN1143863C (en) 2004-03-31
CN1158620A (en) 1997-09-03
ITMI941955A0 (en) 1994-09-27
PL181824B1 (en) 2001-09-28
BG63895B1 (en) 2003-05-30
IT1270017B (en) 1997-04-16

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Legal Events

Date Code Title Description
FA10 Dismissal: dismissal - article 33 of industrial property law