BR9406765A - N-((1-(4-(4-fluorofenoxi)Butil)-4-Piperidinil)-N-Metilamino)-2-Benzotiazolois como agentes antiarritmicos classe III - Google Patents

N-((1-(4-(4-fluorofenoxi)Butil)-4-Piperidinil)-N-Metilamino)-2-Benzotiazolois como agentes antiarritmicos classe III

Info

Publication number
BR9406765A
BR9406765A BR9406765A BR9406765A BR9406765A BR 9406765 A BR9406765 A BR 9406765A BR 9406765 A BR9406765 A BR 9406765A BR 9406765 A BR9406765 A BR 9406765A BR 9406765 A BR9406765 A BR 9406765A
Authority
BR
Brazil
Prior art keywords
pct
fluorophenoxy
piperidinyl
methylamino
butyl
Prior art date
Application number
BR9406765A
Other languages
English (en)
Portuguese (pt)
Inventor
Josef Jan Pieter Heykants
Marcel Jan Maria Borgers
Doris Wilhelm
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of BR9406765A publication Critical patent/BR9406765A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Silver Salt Photography Or Processing Solution Therefor (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
BR9406765A 1993-06-11 1994-06-06 N-((1-(4-(4-fluorofenoxi)Butil)-4-Piperidinil)-N-Metilamino)-2-Benzotiazolois como agentes antiarritmicos classe III BR9406765A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP93201685 1993-06-11
PCT/EP1994/001849 WO1994029305A1 (en) 1993-06-11 1994-06-06 N-[[1-[4-(4-fluorophenoxy)butyl]-4-piperidinyl]-n-methylamino]-2-benzothiazolols as class iii antiarrhythmic agents

Publications (1)

Publication Number Publication Date
BR9406765A true BR9406765A (pt) 1996-02-21

Family

ID=8213890

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9406765A BR9406765A (pt) 1993-06-11 1994-06-06 N-((1-(4-(4-fluorofenoxi)Butil)-4-Piperidinil)-N-Metilamino)-2-Benzotiazolois como agentes antiarritmicos classe III

Country Status (34)

Country Link
US (1) US5691354A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0701556B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JP3498145B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR100337984B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (1) CN1039120C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE159254T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU678841B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BG (1) BG62968B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BR (1) BR9406765A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2163018A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CZ (1) CZ285766B6 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE69406284T2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK0701556T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2108471T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI955916A0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR3025805T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU221620B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL109975A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
LV (1) LV11544B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MY (1) MY111222A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO305123B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ268575A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
OA (1) OA10201A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PH (1) PH31126A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (1) PL176775B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
RO (1) RO115523B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
RU (1) RU2122546C1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SG (1) SG48821A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SI (1) SI9420036A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SK (1) SK281175B6 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TW (1) TW282469B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
UA (1) UA41936C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO1994029305A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA944106B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2258165C (en) * 1996-06-27 2009-03-03 Marc Gaston Venet N-[4-(heteroarylmethyl)phenyl]-heteroarylamines
ATE327230T1 (de) 2000-01-20 2006-06-15 Eisai Co Ltd Piperidinverbindungen und diese enthaltenden medikamente
RU2242254C2 (ru) * 2002-11-05 2004-12-20 ГУ Новосибирский научно-исследовательский институт патологии кровообращения им. акад. Е.Н. Мешалкина Способ диагностики аритмий сердца
RU2246895C2 (ru) * 2002-11-05 2005-02-27 ГУ Новосибирский научно-исследовательский институт патологии кровообращения им. акад. Е.Н. Мешалкина МЗ РФ Способ прогнозирования желудочковых аритмий у кардиохирургических больных
RU2261122C2 (ru) * 2003-02-17 2005-09-27 ГУ Новосибирский научно-исследовательский институт патологии кровообращения им. акад. Е.Н. Мешалкина МЗ РФ Способ определения уровня атриовентрикулярной блокады у больных после хирургической коррекции пороков сердца
RU2261121C2 (ru) * 2003-02-17 2005-09-27 ГУ Новосибирский научно-исследовательский институт патологии кровообращения им. акад. Е.Н. Мешалкина МЗ РФ Способ определения степени зависимости от электрокардиостимулятора
RU2261123C2 (ru) * 2003-02-17 2005-09-27 ГУ Новосибирский научно-исследовательский институт патологии кровообращения им. акад. Е.Н. Мешалкина МЗ РФ Способ прогнозирования атриовентрикулярных блокад после радикальной кардиохирургической коррекции пороков сердца у детей раннего возраста
RU2261124C2 (ru) * 2003-04-24 2005-09-27 ГУ Новосибирский научно-исследовательский институт патологии кровообращения им. акад. Е.Н. Мешалкина МЗ РФ Способ оценки электрических свойств рабочего миокарда
RU2261041C2 (ru) * 2003-04-24 2005-09-27 ГУ Новосибирский научно-исследовательский институт патологии кровообращения им. акад. Е.Н. Мешалкина МЗ РФ Способ прогнозирования пароксизмальной эктопической атриовентрикулярной тахикардии

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1396964A3 (ru) * 1984-01-09 1988-05-15 Жансен Фармасетика Н.В. (Фирма) Способ получени 4-(бициклогетероциклилметил)пиперидинов или их фармацевтически приемлемых солей присоединени кислот
US5010198A (en) * 1984-12-03 1991-04-23 Janssen Pharmaceutica N.V. Intermediates for the synthesis of benzoxazol- and benzothiazolamine derivatives, useful as anti-anoxic agents
US4861785A (en) * 1984-12-03 1989-08-29 Janssen Pharmaceutica N.V. Benzoxazol-and benzothiazolamine derivatives, useful as anti-anoxic agents
CA1260474A (en) * 1984-12-03 1989-09-26 Raymond A. Stokbroekx Benzoxazol- and benzothiazolamine derivatives
US4749702A (en) * 1985-04-15 1988-06-07 Janssen Pharmaceutica N. V. Antidepressive substituted N-[(4-piperidinyl)alkyl] bicyclic condensed oxazol- and thiazolamines
KR930005004B1 (ko) * 1985-04-15 1993-06-11 쟈안센 파아마슈우티카 엔. 부이. 치환된 n-[(4-피페리디닐)알킬]이환 축합 옥사졸아민 및 티아졸아민의 제조방법
ZW1992A1 (en) * 1991-02-25 1993-09-22 Janssen Pharmaceutica Nv 4-/(2-benzotiazolyl)methylamino/-b-/(3,4-difluorephenoxy)methyl/-1-piperidine ethanol

Also Published As

Publication number Publication date
UA41936C2 (uk) 2001-10-15
SG48821A1 (en) 1998-05-18
ZA944106B (en) 1995-12-11
CZ285766B6 (cs) 1999-11-17
KR100337984B1 (ko) 2002-10-25
PH31126A (en) 1998-02-23
DE69406284T2 (de) 1998-02-19
PL311965A1 (en) 1996-03-18
DK0701556T3 (da) 1998-01-26
NO305123B1 (no) 1999-04-06
AU678841B2 (en) 1997-06-12
JPH08511014A (ja) 1996-11-19
HU9501971D0 (en) 1995-09-28
LV11544A (lv) 1996-10-20
RU2122546C1 (ru) 1998-11-27
WO1994029305A1 (en) 1994-12-22
SI9420036A (en) 1996-10-31
RO115523B1 (ro) 2000-03-30
ATE159254T1 (de) 1997-11-15
BG62968B1 (bg) 2000-12-29
IL109975A0 (en) 1994-10-07
LV11544B (en) 1997-08-20
ES2108471T3 (es) 1997-12-16
PL176775B1 (pl) 1999-07-30
GR3025805T3 (en) 1998-03-31
MY111222A (en) 1999-09-30
EP0701556B1 (en) 1997-10-15
NO954801D0 (no) 1995-11-27
CN1125443A (zh) 1996-06-26
AU7183894A (en) 1995-01-03
CN1039120C (zh) 1998-07-15
SK154495A3 (en) 1996-06-05
TW282469B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1996-08-01
HUT73679A (en) 1996-09-30
US5691354A (en) 1997-11-25
CA2163018A1 (en) 1994-12-22
BG100210A (bg) 1996-07-31
FI955916L (fi) 1995-12-08
SK281175B6 (sk) 2000-12-11
EP0701556A1 (en) 1996-03-20
FI955916A7 (fi) 1995-12-08
OA10201A (en) 1996-12-18
JP3498145B2 (ja) 2004-02-16
NO954801L (no) 1995-11-27
NZ268575A (en) 1996-08-27
FI955916A0 (fi) 1995-12-08
IL109975A (en) 1999-04-11
HU221620B1 (hu) 2002-12-28
CZ319295A3 (en) 1996-03-13
DE69406284D1 (de) 1997-11-20

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Legal Events

Date Code Title Description
EG Technical examination (opinion): publication of technical examination (opinion)
FC Decision: refusal
CKFC Appeal: appeal against refusal