BR112023026416A2 - Peptídeos antimicrobianos modificados - Google Patents
Peptídeos antimicrobianos modificadosInfo
- Publication number
- BR112023026416A2 BR112023026416A2 BR112023026416A BR112023026416A BR112023026416A2 BR 112023026416 A2 BR112023026416 A2 BR 112023026416A2 BR 112023026416 A BR112023026416 A BR 112023026416A BR 112023026416 A BR112023026416 A BR 112023026416A BR 112023026416 A2 BR112023026416 A2 BR 112023026416A2
- Authority
- BR
- Brazil
- Prior art keywords
- defensin
- modified
- antimicrobial peptides
- peptides
- modified antimicrobial
- Prior art date
Links
- 102000044503 Antimicrobial Peptides Human genes 0.000 title abstract 2
- 108700042778 Antimicrobial Peptides Proteins 0.000 title abstract 2
- 108010002069 Defensins Proteins 0.000 abstract 3
- 102000000541 Defensins Human genes 0.000 abstract 2
- 241000251539 Vertebrata <Metazoa> Species 0.000 abstract 1
- 230000000845 anti-microbial effect Effects 0.000 abstract 1
- 210000004900 c-terminal fragment Anatomy 0.000 abstract 1
- 238000011109 contamination Methods 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000000813 microbial effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
- A01N63/50—Isolated enzymes; Isolated proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
- A01P1/00—Disinfectants; Antimicrobial compounds or mixtures thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
- A01H5/00—Angiosperms, i.e. flowering plants, characterised by their plant parts; Angiosperms characterised otherwise than by their botanic taxonomy
- A01H5/10—Seeds
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
- A01N37/46—N-acyl derivatives
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
- A01P3/00—Fungicides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4723—Cationic antimicrobial peptides, e.g. defensins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
- C12N15/8282—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for fungal resistance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Plant Pathology (AREA)
- Environmental Sciences (AREA)
- Pest Control & Pesticides (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Agronomy & Crop Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Botany (AREA)
- Dentistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Mycology (AREA)
- General Engineering & Computer Science (AREA)
- Virology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Toxicology (AREA)
Abstract
peptídeos antimicrobianos modificados. a presente invenção refere-se a variantes de peptídeo defensina antimicrobiano que compreendem fragmentos c-terminais modificados de uma defensina e ácidos nucleicos que codificam a mesma. são também reveladas composições que compreendem os peptídeos variantes de defensina e métodos de seu uso para controlar infecções microbianas de plantas e indivíduos vertebrados, assim como a contaminação de rações e alimentos.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US202163202559P | 2021-06-16 | 2021-06-16 | |
US202263365928P | 2022-06-06 | 2022-06-06 | |
PCT/US2022/072971 WO2022266648A1 (en) | 2021-06-16 | 2022-06-16 | Modified antimicrobial peptides |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112023026416A2 true BR112023026416A2 (pt) | 2024-03-05 |
Family
ID=84527663
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112023026416A BR112023026416A2 (pt) | 2021-06-16 | 2022-06-16 | Peptídeos antimicrobianos modificados |
Country Status (7)
Country | Link |
---|---|
US (1) | US20220408731A1 (pt) |
EP (1) | EP4340619A1 (pt) |
KR (1) | KR20240021867A (pt) |
AU (1) | AU2022292802A1 (pt) |
BR (1) | BR112023026416A2 (pt) |
CA (1) | CA3223545A1 (pt) |
WO (1) | WO2022266648A1 (pt) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2024137918A1 (en) * | 2022-12-21 | 2024-06-27 | Donald Danforth Plant Science Center | Antimicrobial peptides and modifications thereof |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6057287A (en) * | 1994-01-11 | 2000-05-02 | Dyax Corp. | Kallikrein-binding "Kunitz domain" proteins and analogues thereof |
US6841657B2 (en) * | 1997-04-17 | 2005-01-11 | Whitehead Institute For Biomedical Research | Inhibitors of HIV membrane fusion |
ATE510015T1 (de) * | 2001-02-08 | 2011-06-15 | Hexima Ltd | Aus pflanzen stammende moleküle und diese codierende genetische sequenzen sowie verwendungen dafür |
BRPI0512904A (pt) * | 2004-06-30 | 2008-04-15 | Pioneer Hi Bred Int | método para o aumento da resistência de plantas a patógenos de fungo |
CA3020883A1 (en) * | 2016-03-11 | 2017-09-14 | Donald Danforth Plant Science Center | Multimeric defensin proteins and related methods |
-
2022
- 2022-06-16 US US17/807,209 patent/US20220408731A1/en active Pending
- 2022-06-16 CA CA3223545A patent/CA3223545A1/en active Pending
- 2022-06-16 WO PCT/US2022/072971 patent/WO2022266648A1/en active Application Filing
- 2022-06-16 EP EP22826025.3A patent/EP4340619A1/en active Pending
- 2022-06-16 BR BR112023026416A patent/BR112023026416A2/pt unknown
- 2022-06-16 KR KR1020247000866A patent/KR20240021867A/ko unknown
- 2022-06-16 AU AU2022292802A patent/AU2022292802A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
AU2022292802A1 (en) | 2024-01-04 |
US20220408731A1 (en) | 2022-12-29 |
EP4340619A1 (en) | 2024-03-27 |
KR20240021867A (ko) | 2024-02-19 |
CA3223545A1 (en) | 2022-12-22 |
WO2022266648A1 (en) | 2022-12-22 |
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