BR112023025333A2 - Métodos de purificação de canabinoides - Google Patents

Métodos de purificação de canabinoides

Info

Publication number
BR112023025333A2
BR112023025333A2 BR112023025333A BR112023025333A BR112023025333A2 BR 112023025333 A2 BR112023025333 A2 BR 112023025333A2 BR 112023025333 A BR112023025333 A BR 112023025333A BR 112023025333 A BR112023025333 A BR 112023025333A BR 112023025333 A2 BR112023025333 A2 BR 112023025333A2
Authority
BR
Brazil
Prior art keywords
cannabinoid
purification methods
methods
purify
compositions
Prior art date
Application number
BR112023025333A
Other languages
English (en)
Inventor
Benjamin Yap
Binita Bhattacharjee
Dominic Valdes
Jenna Lloyd-Randolfi
Rudy Sithirath
Tate Tong
Original Assignee
Amyris Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amyris Inc filed Critical Amyris Inc
Publication of BR112023025333A2 publication Critical patent/BR112023025333A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/22—Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21062—Subtilisin (3.4.21.62)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

métodos de purificação de canabinoides. as composições e métodos da divulgação podem ser usados para purificar um canabinoide em uma célula hospedeira, tal como uma célula de levedura, geneticamente modificada para expressar as enzimas de uma via biossintética de canabinoide. usando as composições e métodos da divulgação, uma composição de fermentação pode ser colocada em contato com uma composição enzimática incluindo uma serina protease para purificar um canabinoide.
BR112023025333A 2021-06-04 2022-06-03 Métodos de purificação de canabinoides BR112023025333A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202163196741P 2021-06-04 2021-06-04
PCT/US2022/032219 WO2022256691A1 (en) 2021-06-04 2022-06-03 Methods of purifying cannabinoid

Publications (1)

Publication Number Publication Date
BR112023025333A2 true BR112023025333A2 (pt) 2024-02-27

Family

ID=84323669

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112023025333A BR112023025333A2 (pt) 2021-06-04 2022-06-03 Métodos de purificação de canabinoides

Country Status (3)

Country Link
EP (1) EP4347854A1 (pt)
BR (1) BR112023025333A2 (pt)
WO (1) WO2022256691A1 (pt)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4519934A (en) * 1983-04-19 1985-05-28 Novo Industri A/S Liquid enzyme concentrates containing alpha-amylase
BRPI0611936A2 (pt) * 2005-06-24 2011-02-22 Solvay Pharm Gmbh protease, uso de uma protease, composição farmacêutica, e, método para o tratamento de doença
CA2902452C (en) * 2013-02-28 2018-09-04 Full Spectrum Laboratories Limited Chemical engineering processes and apparatus for the synthesis of compounds
PL3013967T3 (pl) * 2013-06-24 2022-03-21 Novozymes A/S Sposoby odzyskiwania oleju z procesów wytwarzania produktów fermentacji i sposoby wytwarzania produktów fermentacji
US20180312886A1 (en) * 2014-04-10 2018-11-01 Cargill Incorporated Microbial production of chemical products and related compositions, methods and systems

Also Published As

Publication number Publication date
EP4347854A1 (en) 2024-04-10
WO2022256691A1 (en) 2022-12-08
WO2022256691A8 (en) 2023-01-12

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