BR112023021606A2 - Formas sólidas de modulador de hemoglobina - Google Patents

Formas sólidas de modulador de hemoglobina

Info

Publication number
BR112023021606A2
BR112023021606A2 BR112023021606A BR112023021606A BR112023021606A2 BR 112023021606 A2 BR112023021606 A2 BR 112023021606A2 BR 112023021606 A BR112023021606 A BR 112023021606A BR 112023021606 A BR112023021606 A BR 112023021606A BR 112023021606 A2 BR112023021606 A2 BR 112023021606A2
Authority
BR
Brazil
Prior art keywords
solid forms
forms
compound
hemoglobin
modulator
Prior art date
Application number
BR112023021606A
Other languages
English (en)
Portuguese (pt)
Inventor
S Johnson Courtney
Fang Wang
D Parent Stephan
Lee Houston Travis
Original Assignee
Global Blood Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Global Blood Therapeutics Inc filed Critical Global Blood Therapeutics Inc
Publication of BR112023021606A2 publication Critical patent/BR112023021606A2/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
BR112023021606A 2021-05-14 2022-05-13 Formas sólidas de modulador de hemoglobina BR112023021606A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202163188833P 2021-05-14 2021-05-14
PCT/US2022/029289 WO2022241278A1 (en) 2021-05-14 2022-05-13 Solid forms of a modulator of hemoglobin

Publications (1)

Publication Number Publication Date
BR112023021606A2 true BR112023021606A2 (pt) 2023-12-19

Family

ID=82020064

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112023021606A BR112023021606A2 (pt) 2021-05-14 2022-05-13 Formas sólidas de modulador de hemoglobina

Country Status (13)

Country Link
US (2) US11851424B2 (https=)
EP (1) EP4337659A1 (https=)
JP (1) JP2024520897A (https=)
KR (1) KR20240008356A (https=)
CN (1) CN117337285A (https=)
AR (1) AR126649A1 (https=)
AU (1) AU2022273787B2 (https=)
BR (1) BR112023021606A2 (https=)
CA (1) CA3219786A1 (https=)
MX (1) MX2023012156A (https=)
TW (1) TW202311254A (https=)
WO (1) WO2022241278A1 (https=)
ZA (1) ZA202309517B (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20250041312A1 (en) * 2021-12-10 2025-02-06 Global Blood Therapeutics, Inc. Methods of administering a modulator of hemoglobin
TW202515579A (zh) * 2023-06-13 2025-04-16 美商全球血液治療公司 投予血紅素的調節劑之方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3845770A (en) 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
US4326525A (en) 1980-10-14 1982-04-27 Alza Corporation Osmotic device that improves delivery properties of agent in situ
US4432987A (en) * 1982-04-23 1984-02-21 Pfizer Inc. Crystalline benzenesulfonate salts of sultamicillin
US5364620A (en) 1983-12-22 1994-11-15 Elan Corporation, Plc Controlled absorption diltiazem formulation for once daily administration
US5023252A (en) 1985-12-04 1991-06-11 Conrex Pharmaceutical Corporation Transdermal and trans-membrane delivery of drugs
US5001139A (en) 1987-06-12 1991-03-19 American Cyanamid Company Enchancers for the transdermal flux of nivadipine
US4992445A (en) 1987-06-12 1991-02-12 American Cyanamid Co. Transdermal delivery of pharmaceuticals
US4902514A (en) 1988-07-21 1990-02-20 Alza Corporation Dosage form for administering nilvadipine for treating cardiovascular symptoms
SG10201802911RA (en) * 2013-03-15 2018-05-30 Global Blood Therapeutics Inc Compounds and uses thereof for the modulation of hemoglobin
HRP20220295T1 (hr) 2018-11-19 2022-05-13 Global Blood Therapeutics, Inc. Spojevi 2-formil-3-hidroksifeniloksimetila koji mogu modulirati hemoglobin
WO2022241286A1 (en) * 2021-05-14 2022-11-17 Global Blood Therapeutics, Inc. Methods of making a modulator of hemoglobin

Also Published As

Publication number Publication date
MX2023012156A (es) 2023-10-26
CN117337285A (zh) 2024-01-02
ZA202309517B (en) 2024-06-26
EP4337659A1 (en) 2024-03-20
US20220363674A1 (en) 2022-11-17
US11851424B2 (en) 2023-12-26
AR126649A1 (es) 2023-11-01
US12473277B2 (en) 2025-11-18
AU2022273787B2 (en) 2025-04-03
JP2024520897A (ja) 2024-05-27
AU2022273787A1 (en) 2023-10-26
TW202311254A (zh) 2023-03-16
US20240076290A1 (en) 2024-03-07
CA3219786A1 (en) 2022-11-17
KR20240008356A (ko) 2024-01-18
WO2022241278A1 (en) 2022-11-17

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