MX2023012156A - Formas solidas de un modulador de hemoglobina. - Google Patents

Formas solidas de un modulador de hemoglobina.

Info

Publication number
MX2023012156A
MX2023012156A MX2023012156A MX2023012156A MX2023012156A MX 2023012156 A MX2023012156 A MX 2023012156A MX 2023012156 A MX2023012156 A MX 2023012156A MX 2023012156 A MX2023012156 A MX 2023012156A MX 2023012156 A MX2023012156 A MX 2023012156A
Authority
MX
Mexico
Prior art keywords
hemoglobin
modulator
solid forms
forms
compound
Prior art date
Application number
MX2023012156A
Other languages
English (en)
Inventor
Fang Wang
Stephan D Parent
Courtney S Johnson
Travis Lee Houston
Original Assignee
Global Blood Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Global Blood Therapeutics Inc filed Critical Global Blood Therapeutics Inc
Publication of MX2023012156A publication Critical patent/MX2023012156A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Se prepararon y caracterizaron formas en estado sólido de (S)-2-hidroxi-6-((4-(2-(2-hidroxietil)nicotinoil)morfolin-3-il)me toxi)benzaldehído (Compuesto I), o sus sales o solvatos. También se proporcionan procesos de fabricación y métodos de uso de las formas del Compuesto I.
MX2023012156A 2021-05-14 2022-05-13 Formas solidas de un modulador de hemoglobina. MX2023012156A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202163188833P 2021-05-14 2021-05-14
PCT/US2022/029289 WO2022241278A1 (en) 2021-05-14 2022-05-13 Solid forms of a modulator of hemoglobin

Publications (1)

Publication Number Publication Date
MX2023012156A true MX2023012156A (es) 2023-10-26

Family

ID=82020064

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2023012156A MX2023012156A (es) 2021-05-14 2022-05-13 Formas solidas de un modulador de hemoglobina.

Country Status (12)

Country Link
US (2) US11851424B2 (es)
EP (1) EP4337659A1 (es)
JP (1) JP2024520897A (es)
KR (1) KR20240008356A (es)
CN (1) CN117337285A (es)
AR (1) AR126649A1 (es)
AU (1) AU2022273787A1 (es)
BR (1) BR112023021606A2 (es)
CA (1) CA3219786A1 (es)
MX (1) MX2023012156A (es)
TW (1) TW202311254A (es)
WO (1) WO2022241278A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023107697A1 (en) * 2021-12-10 2023-06-15 Global Blood Therapeutics, Inc. Methods of administering a modulator of hemoglobin

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3845770A (en) 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
US4326525A (en) 1980-10-14 1982-04-27 Alza Corporation Osmotic device that improves delivery properties of agent in situ
US5364620A (en) 1983-12-22 1994-11-15 Elan Corporation, Plc Controlled absorption diltiazem formulation for once daily administration
US5023252A (en) 1985-12-04 1991-06-11 Conrex Pharmaceutical Corporation Transdermal and trans-membrane delivery of drugs
US5001139A (en) 1987-06-12 1991-03-19 American Cyanamid Company Enchancers for the transdermal flux of nivadipine
US4992445A (en) 1987-06-12 1991-02-12 American Cyanamid Co. Transdermal delivery of pharmaceuticals
US4902514A (en) 1988-07-21 1990-02-20 Alza Corporation Dosage form for administering nilvadipine for treating cardiovascular symptoms
RS62970B1 (sr) 2018-11-19 2022-03-31 Global Blood Therapeutics Inc 2-formil-3-hidroksifeniloksimetil jedinjenja sposobna da moduliraju hemoglobin

Also Published As

Publication number Publication date
TW202311254A (zh) 2023-03-16
BR112023021606A2 (pt) 2023-12-19
CN117337285A (zh) 2024-01-02
JP2024520897A (ja) 2024-05-27
AR126649A1 (es) 2023-11-01
US20220363674A1 (en) 2022-11-17
US20240076290A1 (en) 2024-03-07
AU2022273787A1 (en) 2023-10-26
EP4337659A1 (en) 2024-03-20
KR20240008356A (ko) 2024-01-18
US11851424B2 (en) 2023-12-26
WO2022241278A1 (en) 2022-11-17
CA3219786A1 (en) 2022-11-17

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