BR112023019622A2 - Preparação contendo composto de peptídeo cíclico e método para a produção do mesmo - Google Patents
Preparação contendo composto de peptídeo cíclico e método para a produção do mesmoInfo
- Publication number
- BR112023019622A2 BR112023019622A2 BR112023019622A BR112023019622A BR112023019622A2 BR 112023019622 A2 BR112023019622 A2 BR 112023019622A2 BR 112023019622 A BR112023019622 A BR 112023019622A BR 112023019622 A BR112023019622 A BR 112023019622A BR 112023019622 A2 BR112023019622 A2 BR 112023019622A2
- Authority
- BR
- Brazil
- Prior art keywords
- producing
- same
- cyclic peptide
- preparation containing
- containing cyclic
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 108010069514 Cyclic Peptides Proteins 0.000 title abstract 2
- 102000001189 Cyclic Peptides Human genes 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 239000000654 additive Substances 0.000 abstract 1
- 230000000996 additive effect Effects 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
- A61K9/4825—Proteins, e.g. gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021079015 | 2021-05-07 | ||
| PCT/JP2022/019540 WO2022234850A1 (ja) | 2021-05-07 | 2022-05-06 | 環状ペプチド化合物を含む製剤及びその製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112023019622A2 true BR112023019622A2 (pt) | 2023-11-14 |
Family
ID=83932759
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112023019622A BR112023019622A2 (pt) | 2021-05-07 | 2022-05-06 | Preparação contendo composto de peptídeo cíclico e método para a produção do mesmo |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20240366711A1 (https=) |
| EP (1) | EP4299069A4 (https=) |
| JP (2) | JP7181442B1 (https=) |
| KR (2) | KR20230169093A (https=) |
| CN (1) | CN117241817A (https=) |
| AU (1) | AU2022270498A1 (https=) |
| BR (1) | BR112023019622A2 (https=) |
| CA (1) | CA3219090A1 (https=) |
| IL (1) | IL306018A (https=) |
| MX (1) | MX2023013099A (https=) |
| TW (1) | TW202308679A (https=) |
| WO (1) | WO2022234850A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW202446781A (zh) | 2011-12-28 | 2024-12-01 | 日商中外製藥股份有限公司 | 胜肽化合物之製造方法 |
| BR112022007535A2 (pt) | 2019-11-07 | 2022-07-12 | Chugai Pharmaceutical Co Ltd | Composto peptídico cíclico tendo ação inibitória de kras |
| US12312379B2 (en) | 2021-05-07 | 2025-05-27 | Chugai Seiyaku Kabushiki Kaisha | Methods for producing cyclic compounds comprising N-substituted amino acid residues |
| JP7823181B2 (ja) | 2022-05-06 | 2026-03-03 | 中外製薬株式会社 | Ｈｒａｓおよびｎｒａｓに対して選択的なｋｒａｓ阻害作用を有する環状化合物 |
| TW202430537A (zh) * | 2022-10-20 | 2024-08-01 | 日商中外製藥股份有限公司 | 環狀胜肽的結晶的製造方法 |
| CN120936619A (zh) * | 2023-04-20 | 2025-11-11 | 中外制药株式会社 | 用于生产环肽化合物的方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103347532A (zh) * | 2011-02-04 | 2013-10-09 | 爱奇司治疗公司 | 口服可生物利用肽药物组合物及其方法 |
| ES2586411T3 (es) | 2011-03-04 | 2016-10-14 | New York University | Macrociclos sustitutos de enlace de hidrógeno como moduladores de Ras |
| TW202446781A (zh) | 2011-12-28 | 2024-12-01 | 日商中外製藥股份有限公司 | 胜肽化合物之製造方法 |
| JP6716582B2 (ja) | 2014-11-07 | 2020-07-01 | サブリミティ・セラピューティクス・リミテッドＳｕｂｌｉｍｉｔｙ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｌｉｍｉｔｅｄ | シクロスポリンを含む組成物 |
| US10954287B2 (en) | 2016-04-15 | 2021-03-23 | Ra Pharmaceuticals, Inc. | Ras binding peptides and methods of use |
| WO2018031730A2 (en) | 2016-08-11 | 2018-02-15 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Peptide inhibitors of phosphoglycerate mutase and methods of use |
| CN110869544B (zh) | 2017-06-09 | 2024-03-08 | 中外制药株式会社 | 膜透过性高的环状肽化合物及包含其的文库 |
| WO2020122182A1 (ja) | 2018-12-12 | 2020-06-18 | 中外製薬株式会社 | 分子内水素結合可能な官能基を有するアミノ酸とそれらのアミノ酸を含むペプチド化合物、およびそれらの製造方法 |
| BR112022007535A2 (pt) * | 2019-11-07 | 2022-07-12 | Chugai Pharmaceutical Co Ltd | Composto peptídico cíclico tendo ação inibitória de kras |
| US12312379B2 (en) * | 2021-05-07 | 2025-05-27 | Chugai Seiyaku Kabushiki Kaisha | Methods for producing cyclic compounds comprising N-substituted amino acid residues |
-
2022
- 2022-05-06 TW TW111117094A patent/TW202308679A/zh unknown
- 2022-05-06 KR KR1020237032063A patent/KR20230169093A/ko not_active Withdrawn
- 2022-05-06 IL IL306018A patent/IL306018A/en unknown
- 2022-05-06 CN CN202280029838.6A patent/CN117241817A/zh active Pending
- 2022-05-06 US US18/289,392 patent/US20240366711A1/en active Pending
- 2022-05-06 EP EP22798954.8A patent/EP4299069A4/en not_active Withdrawn
- 2022-05-06 AU AU2022270498A patent/AU2022270498A1/en not_active Abandoned
- 2022-05-06 MX MX2023013099A patent/MX2023013099A/es unknown
- 2022-05-06 KR KR1020237001877A patent/KR102582225B1/ko active Active
- 2022-05-06 WO PCT/JP2022/019540 patent/WO2022234850A1/ja not_active Ceased
- 2022-05-06 CA CA3219090A patent/CA3219090A1/en active Pending
- 2022-05-06 BR BR112023019622A patent/BR112023019622A2/pt unknown
- 2022-05-06 JP JP2022548967A patent/JP7181442B1/ja active Active
- 2022-11-17 JP JP2022184220A patent/JP2023015334A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| KR102582225B1 (ko) | 2023-09-22 |
| JPWO2022234850A1 (https=) | 2022-11-10 |
| IL306018A (en) | 2023-11-01 |
| KR20230020548A (ko) | 2023-02-10 |
| EP4299069A4 (en) | 2025-03-05 |
| TW202308679A (zh) | 2023-03-01 |
| CN117241817A (zh) | 2023-12-15 |
| EP4299069A1 (en) | 2024-01-03 |
| US20240366711A1 (en) | 2024-11-07 |
| MX2023013099A (es) | 2023-11-17 |
| CA3219090A1 (en) | 2022-11-10 |
| JP7181442B1 (ja) | 2022-11-30 |
| JP2023015334A (ja) | 2023-01-31 |
| AU2022270498A1 (en) | 2023-10-05 |
| WO2022234850A1 (ja) | 2022-11-10 |
| KR20230169093A (ko) | 2023-12-15 |
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