BR112023003735A2 - Processo de purificação para a preparação de cobre-64 não adicionado ao veículo - Google Patents
Processo de purificação para a preparação de cobre-64 não adicionado ao veículoInfo
- Publication number
- BR112023003735A2 BR112023003735A2 BR112023003735A BR112023003735A BR112023003735A2 BR 112023003735 A2 BR112023003735 A2 BR 112023003735A2 BR 112023003735 A BR112023003735 A BR 112023003735A BR 112023003735 A BR112023003735 A BR 112023003735A BR 112023003735 A2 BR112023003735 A2 BR 112023003735A2
- Authority
- BR
- Brazil
- Prior art keywords
- copper
- vehicle
- preparation
- added
- compositions
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
- G21G1/00—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
- G21G1/001—Recovery of specific isotopes from irradiated targets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
- C01G3/00—Compounds of copper
- C01G3/003—Preparation involving a liquid-liquid extraction, an adsorption or an ion-exchange
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
- C01G3/00—Compounds of copper
- C01G3/04—Halides
- C01G3/05—Chlorides
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
- G21G1/00—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
- G21G1/04—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes outside nuclear reactors or particle accelerators
- G21G1/10—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes outside nuclear reactors or particle accelerators by bombardment with electrically charged particles
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
- G21G4/00—Radioactive sources
- G21G4/04—Radioactive sources other than neutron sources
- G21G4/06—Radioactive sources other than neutron sources characterised by constructional features
- G21G4/08—Radioactive sources other than neutron sources characterised by constructional features specially adapted for medical application
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
- G21G1/00—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
- G21G1/001—Recovery of specific isotopes from irradiated targets
- G21G2001/0094—Other isotopes not provided for in the groups listed above
Landscapes
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- High Energy & Nuclear Physics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Inorganic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Optics & Photonics (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Manufacture And Refinement Of Metals (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Catalysts (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Abstract
PROCESSO DE PURIFICAÇÃO PARA A PREPARAÇÃO DE COBRE-64 NÃO ADICIONADO AO VEÍCULO. A presente invenção refere-se a composições compreendendo altos níveis de cobre-64 de alta atividade específica e processo para preparar as referidas composições. As composições compreendem de cerca de 2 Ci a cerca de 15 Ci de cobre-64 e têm atividades específicas de até cerca de 3.800 mCi de cobre-64 por micrograma de cobre. Os processos para preparar as referidas composições compreendem bombardear um alvo de níquel-64 com um feixe de prótons de baixa energia e alta corrente e purificar o cobre-64 de outros metais por um processo compreendendo cromatografia de troca iônica ou um processo compreendendo uma combinação de cromatografia de extração e cromatografia de troca iônica.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063074356P | 2020-09-03 | 2020-09-03 | |
| PCT/US2021/049039 WO2022051608A1 (en) | 2020-09-03 | 2021-09-03 | Purification process for the preparation of non-carrier added copper-64 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112023003735A2 true BR112023003735A2 (pt) | 2023-03-28 |
Family
ID=80356384
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112023003735A BR112023003735A2 (pt) | 2020-09-03 | 2021-09-03 | Processo de purificação para a preparação de cobre-64 não adicionado ao veículo |
Country Status (10)
| Country | Link |
|---|---|
| US (7) | US11521762B2 (pt) |
| EP (1) | EP4208625A1 (pt) |
| JP (1) | JP2023540498A (pt) |
| KR (1) | KR20230058683A (pt) |
| CN (1) | CN116157586A (pt) |
| AU (1) | AU2021335596A1 (pt) |
| BR (1) | BR112023003735A2 (pt) |
| CA (1) | CA3192205A1 (pt) |
| MX (1) | MX2023002608A (pt) |
| WO (1) | WO2022051608A1 (pt) |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU7265096A (en) * | 1995-08-09 | 1997-03-12 | Newton Scientific, Inc. | Production of 64cu and other radionuclides using charged-particle accelerator |
| JP2007512118A (ja) | 2003-08-08 | 2007-05-17 | ワシントン ユニバーシティ イン セント ルイス | ６０Ｃｕ、６１Ｃｕ、および６４Ｃｕ放射性核種の自動分離、精製、および標識装置とその回収 |
| JP4877863B2 (ja) | 2008-06-30 | 2012-02-15 | 独立行政法人日本原子力研究開発機構 | キレート交換樹脂を用いた放射性銅の分離方法 |
| KR101041181B1 (ko) | 2009-01-21 | 2011-06-13 | 재단법인 한국원자력의학원 | Ｃｕ-64를 제조하기 위해 Ｃｕ-64가 형성된 Ｎｉ-64 농축 표적으로부터 Ｃｕ-64를 분리하는 방법 |
| KR101041180B1 (ko) | 2009-01-21 | 2011-06-13 | 재단법인 한국원자력의학원 | Ｎｉ-64를 회수하여 Ｎｉ-64 농축표적의 제조에 재활용하는Ｃｕ-64의 제조방법 |
| JP5880931B2 (ja) | 2011-11-30 | 2016-03-09 | 住友重機械工業株式会社 | ６４Ｃｕの分離精製方法及び６４Ｃｕの分離精製装置 |
| JP7288261B2 (ja) | 2018-04-19 | 2023-06-07 | 国立大学法人高知大学 | 分離装置、分離方法、ｒｉ分離精製システムおよびｒｉ分離精製方法 |
-
2021
- 2021-09-03 WO PCT/US2021/049039 patent/WO2022051608A1/en unknown
- 2021-09-03 MX MX2023002608A patent/MX2023002608A/es unknown
- 2021-09-03 BR BR112023003735A patent/BR112023003735A2/pt unknown
- 2021-09-03 US US17/466,443 patent/US11521762B2/en active Active
- 2021-09-03 CN CN202180053933.5A patent/CN116157586A/zh active Pending
- 2021-09-03 JP JP2023514725A patent/JP2023540498A/ja active Pending
- 2021-09-03 CA CA3192205A patent/CA3192205A1/en active Pending
- 2021-09-03 EP EP21865183.4A patent/EP4208625A1/en active Pending
- 2021-09-03 AU AU2021335596A patent/AU2021335596A1/en active Pending
- 2021-09-03 KR KR1020237010788A patent/KR20230058683A/ko unknown
-
2022
- 2022-08-24 US US17/894,874 patent/US11581103B2/en active Active
- 2022-11-23 US US17/993,186 patent/US11798701B2/en active Active
-
2023
- 2023-06-22 US US18/213,194 patent/US11972874B2/en active Active
- 2023-08-28 US US18/238,966 patent/US11978569B2/en active Active
- 2023-08-28 US US18/238,972 patent/US20230402199A1/en active Pending
- 2023-08-28 US US18/238,951 patent/US20230420152A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US11581103B2 (en) | 2023-02-14 |
| US11521762B2 (en) | 2022-12-06 |
| EP4208625A1 (en) | 2023-07-12 |
| US20230420152A1 (en) | 2023-12-28 |
| CA3192205A1 (en) | 2022-03-10 |
| CN116157586A (zh) | 2023-05-23 |
| WO2022051608A1 (en) | 2022-03-10 |
| US11798701B2 (en) | 2023-10-24 |
| US20220406483A1 (en) | 2022-12-22 |
| US11978569B2 (en) | 2024-05-07 |
| US20230402199A1 (en) | 2023-12-14 |
| US20230411032A1 (en) | 2023-12-21 |
| MX2023002608A (es) | 2023-07-07 |
| US11972874B2 (en) | 2024-04-30 |
| KR20230058683A (ko) | 2023-05-03 |
| AU2021335596A1 (en) | 2023-03-09 |
| US20230081594A1 (en) | 2023-03-16 |
| US20220064015A1 (en) | 2022-03-03 |
| JP2023540498A (ja) | 2023-09-25 |
| US20230352203A1 (en) | 2023-11-02 |
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