BR112022026247A2 - Método para aumentar a eficácia terapêutica de um agente de imunoterapia, método de tratamento de câncer e método de inibição do crescimento de uma célula de câncer - Google Patents
Método para aumentar a eficácia terapêutica de um agente de imunoterapia, método de tratamento de câncer e método de inibição do crescimento de uma célula de câncerInfo
- Publication number
- BR112022026247A2 BR112022026247A2 BR112022026247A BR112022026247A BR112022026247A2 BR 112022026247 A2 BR112022026247 A2 BR 112022026247A2 BR 112022026247 A BR112022026247 A BR 112022026247A BR 112022026247 A BR112022026247 A BR 112022026247A BR 112022026247 A2 BR112022026247 A2 BR 112022026247A2
- Authority
- BR
- Brazil
- Prior art keywords
- cancer
- immunotherapy agent
- inhibiting
- growth
- treatment
- Prior art date
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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- C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| US202063044926P | 2020-06-26 | 2020-06-26 | |
| PCT/US2021/039248 WO2021263205A1 (en) | 2020-06-26 | 2021-06-25 | Combination therapy with deoxyuridine triphosphatase inhibitors |
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| BR112022026247A2 true BR112022026247A2 (pt) | 2023-01-17 |
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| CN116271008A (zh) * | 2022-12-30 | 2023-06-23 | 广东天普生化医药股份有限公司 | 含有安柯瑞和卡瑞利珠单抗的药物组合物及其应用 |
| GB202308160D0 (en) * | 2023-05-31 | 2023-07-12 | Lario Therapeutics Ltd | Compounds |
| GB202308164D0 (en) * | 2023-05-31 | 2023-07-12 | Lario Therapeutics Ltd | Compounds |
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| CN116769722B (zh) * | 2023-07-04 | 2024-07-16 | 杭州荣谷生物科技有限公司 | 功能增强型car-nk细胞、其制备方法及其在免疫疗法中的应用 |
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| US5962246A (en) | 1996-03-29 | 1999-10-05 | The University Of Medicine And Dentistry Of New Jersey | dUTPase, its isoforms, and diagnostic and other uses |
| US8530490B2 (en) | 2008-06-03 | 2013-09-10 | Taiho Pharmaceutical Co., Ltd. | Uracil compound or salt thereof having human deoxyuridine triphosphatase inhibitory activity |
| US20110212467A1 (en) | 2008-08-27 | 2011-09-01 | University Of Southern California | INHIBITORS OF dUTPase |
| CN103948599B (zh) | 2009-11-30 | 2016-03-09 | 大鹏药品工业株式会社 | 抗肿瘤效果增强剂 |
| CA2914178C (en) | 2013-01-07 | 2023-06-13 | University Of Southern California | Deoxyuridine triphosphatase inhibitors |
| US20140274961A1 (en) | 2013-03-15 | 2014-09-18 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| WO2017006271A1 (en) | 2015-07-08 | 2017-01-12 | University Of Southern California | Deoxyuridine triphosphatase inhibitors containing amino sulfonyl linkage |
| PT3319939T (pt) * | 2015-07-08 | 2025-03-05 | Cv6 Therapeutics Ni Ltd | Inibidores de desoxiuridina-trifosfatase contendo hidantoína |
| WO2017119484A1 (ja) * | 2016-01-08 | 2017-07-13 | 大鵬薬品工業株式会社 | 免疫調節剤を含有する抗腫瘍剤及び抗腫瘍効果増強剤 |
| US11014924B2 (en) | 2016-11-23 | 2021-05-25 | Cv6 Therapeutics (Ni) Limited | Hydantoin containing deoxyuridine triphosphatase inhibitors |
| US10829457B2 (en) | 2016-11-23 | 2020-11-10 | Cv6 Therapeutics (Ni) Limited | Nitrogen ring linked deoxyuridine triphosphatase inhibitors |
| US11168059B2 (en) | 2016-11-23 | 2021-11-09 | Cv6 Therapeutics (Ni) Limited | Amino sulfonyl compounds |
| US10858344B2 (en) | 2016-11-23 | 2020-12-08 | Cv6 Therapeutics (Ni) Limited | Hydantoin containing deoxyuridine triphosphatase inhibitors |
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