BR112022024470A2 - Vacina do vetor adenoviral sars-cov-2 recombinante, uso de um gene da proteína s de sars-cov-2 e uso de um adenovírus recombinante - Google Patents

Vacina do vetor adenoviral sars-cov-2 recombinante, uso de um gene da proteína s de sars-cov-2 e uso de um adenovírus recombinante

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Publication number
BR112022024470A2
BR112022024470A2 BR112022024470A BR112022024470A BR112022024470A2 BR 112022024470 A2 BR112022024470 A2 BR 112022024470A2 BR 112022024470 A BR112022024470 A BR 112022024470A BR 112022024470 A BR112022024470 A BR 112022024470A BR 112022024470 A2 BR112022024470 A2 BR 112022024470A2
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BR
Brazil
Prior art keywords
cov
vaccine
sars
recombinant
protein
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BR112022024470A
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English (en)
Inventor
Li Junqiang
Si Weixue
Zhu Tao
Xu Yunli
Deng Jie
Chao Shoubai
Original Assignee
Cansino Biologics Inc
Acad Of Military Medical Sciences Pla
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Application filed by Cansino Biologics Inc, Acad Of Military Medical Sciences Pla filed Critical Cansino Biologics Inc
Publication of BR112022024470A2 publication Critical patent/BR112022024470A2/pt

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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/215—Coronaviridae, e.g. avian infectious bronchitis virus
    • A—HUMAN NECESSITIES
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    • A61P31/12—Antivirals
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Abstract

VACINA DO VETOR ADENOVIRAL SARS-COV-2 RECOMBINANTE, USO DE UM GENE DA PROTEÍNA S DE SARS-COV-2 E USO DE UM ADENOVÍRUS RECOMBINANTE. Divulga-se uma vacina SAR-CoV-2, para a qual a proteína S de SAR-CoV-2 serve como antígeno, a forma da vacina compreende uma vacina vetorial adenoviral, e a vacina produz uma resposta imunológica com características protetoras aprimorada por meio de imunidade transmucosa, prevenindo assim a infecção pelo SAR-CoV-2. Especificamente, a vacina é nebulizada por equipamentos adequados para produzir partículas homogêneas que podem ser inaladas nasal ou oralmente para alcançar os pulmões, produzindo assim uma resposta imunológica protetora em todo o trato respiratório, bem como nos pulmões, aperfeiçoando a utilização eficaz da vacina e melhorando sua eficácia.
BR112022024470A 2020-06-01 2021-04-01 Vacina do vetor adenoviral sars-cov-2 recombinante, uso de um gene da proteína s de sars-cov-2 e uso de um adenovírus recombinante BR112022024470A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN202010485668 2020-06-01
CN202010866719.9A CN113750227A (zh) 2020-06-01 2020-08-24 一种SARS-CoV-2疫苗
PCT/CN2021/084806 WO2021244120A1 (zh) 2020-06-01 2021-04-01 一种SARS-CoV-2疫苗

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BR112022024470A2 true BR112022024470A2 (pt) 2023-05-02

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US (1) US20230173058A1 (pt)
EP (1) EP4159234A1 (pt)
CN (1) CN113750227A (pt)
BR (1) BR112022024470A2 (pt)
CA (1) CA3177300A1 (pt)
WO (1) WO2021244120A1 (pt)

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CN114617972B (zh) * 2020-12-11 2023-12-01 康希诺生物股份公司 一种药物组合物及其应用
WO2023109740A1 (zh) * 2021-12-13 2023-06-22 康希诺生物股份公司 一种重组腺病毒载体疫苗吸入给药递送系统
CN114150005B (zh) * 2022-02-09 2022-04-22 广州恩宝生物医药科技有限公司 用于预防SARS-CoV-2奥密克戎株的腺病毒载体疫苗
WO2023166054A1 (en) * 2022-03-02 2023-09-07 ISR Immune System Regulation Holding AB (publ) Vaccine composition comprising an antigen and a tlr3 agonist
WO2024073362A2 (en) * 2022-09-29 2024-04-04 Board Of Regents, The University Of Texas System Methods and compositions for transport, storage, and delivery of nucleic acids and other molecules

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CN100475268C (zh) * 2004-01-17 2009-04-08 上海三维生物技术有限公司 重组腺病毒冻干制剂及制备方法
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CN110974950B (zh) * 2020-03-05 2020-08-07 广州恩宝生物医药科技有限公司 一种用于预防SARS-CoV-2感染的腺病毒载体疫苗
CN111088283B (zh) * 2020-03-20 2020-06-23 苏州奥特铭医药科技有限公司 mVSV病毒载体及其病毒载体疫苗、一种基于mVSV介导的新冠肺炎疫苗

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CA3177300A1 (en) 2021-12-09
CN113750227A (zh) 2021-12-07
EP4159234A1 (en) 2023-04-05
WO2021244120A1 (zh) 2021-12-09

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