BR112022023413A2 - Tratamento de rugas faciais com toxina botulínica de alta dose e baixo volume - Google Patents
Tratamento de rugas faciais com toxina botulínica de alta dose e baixo volumeInfo
- Publication number
- BR112022023413A2 BR112022023413A2 BR112022023413A BR112022023413A BR112022023413A2 BR 112022023413 A2 BR112022023413 A2 BR 112022023413A2 BR 112022023413 A BR112022023413 A BR 112022023413A BR 112022023413 A BR112022023413 A BR 112022023413A BR 112022023413 A2 BR112022023413 A2 BR 112022023413A2
- Authority
- BR
- Brazil
- Prior art keywords
- botulinum toxin
- treatment
- facial wrinkles
- low volume
- high dose
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
- A61K38/4893—Botulinum neurotoxin (3.4.24.69)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/24—Metalloendopeptidases (3.4.24)
- C12Y304/24069—Bontoxilysin (3.4.24.69), i.e. botulinum neurotoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/91—Injection
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Birds (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Cosmetics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20178574 | 2020-06-05 | ||
| PCT/EP2021/064986 WO2021245223A1 (en) | 2020-06-05 | 2021-06-04 | High dose and low volume botulinum toxin treatment of facial wrinkles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112022023413A2 true BR112022023413A2 (pt) | 2022-12-20 |
Family
ID=71016459
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112022023413A BR112022023413A2 (pt) | 2020-06-05 | 2021-06-04 | Tratamento de rugas faciais com toxina botulínica de alta dose e baixo volume |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US12599550B2 (https=) |
| EP (2) | EP4161562B1 (https=) |
| JP (1) | JP2023529095A (https=) |
| KR (1) | KR20230020961A (https=) |
| CN (1) | CN115666629A (https=) |
| AU (1) | AU2021286196A1 (https=) |
| BR (1) | BR112022023413A2 (https=) |
| CA (1) | CA3177835A1 (https=) |
| ES (1) | ES3013130T3 (https=) |
| IL (1) | IL298399A (https=) |
| MX (1) | MX2022014564A (https=) |
| TW (1) | TW202214211A (https=) |
| WO (1) | WO2021245223A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL298399A (en) | 2020-06-05 | 2023-01-01 | Merz Pharma Gmbh & Co Kgaa | Treatment of facial wrinkles with the botulinum toxin in high dose and low volume |
| KR20240169045A (ko) * | 2022-04-01 | 2024-12-02 | 충칭 클라루비스 파마슈티컬 컴퍼니 리미티드 | 보툴리눔 독소 단백질 조성물, 이의 제조 방법 및 용도 |
| EP4626556A1 (en) * | 2022-11-28 | 2025-10-08 | Merz Pharma GmbH & Co. KGaA | High concentration botulinum toxin treatment for neck rejuvenation |
| WO2025231403A1 (en) * | 2024-05-03 | 2025-11-06 | Revivity Pharma Corporation | Methods of administering and manufacturing toxic compounds |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19925739A1 (de) | 1999-06-07 | 2000-12-21 | Biotecon Ges Fuer Biotechnologische Entwicklung & Consulting Mbh | Therapeutikum mit einem Botulinum-Neurotoxin |
| US7691394B2 (en) * | 2002-05-28 | 2010-04-06 | Botulinum Toxin Research Associates, Inc. | High-potency botulinum toxin formulations |
| DE10333317A1 (de) * | 2003-07-22 | 2005-02-17 | Biotecon Therapeutics Gmbh | Formulierung für Proteinarzneimittel ohne Zusatz von humanem Serumalbumin (HSA) |
| BRPI0513850A (pt) | 2004-07-26 | 2008-05-20 | Merz Pharma Gmbh & Co Kgaa | composição terapêutica com uma neurotoxina botulìnica |
| EP2072039A1 (en) * | 2007-12-21 | 2009-06-24 | Merz Pharma GmbH & Co.KGaA | Use of a neurotoxic component of Clostridium botulinum toxin complex to reduce or prevent side effects |
| PL2271670T3 (pl) | 2008-03-14 | 2015-05-29 | Allergan Inc | Testy aktywności serotypu A toksyny botulinowej oparte na immunologii |
| HUE037509T2 (hu) * | 2011-09-29 | 2018-09-28 | Cellsnap Llc | Készítmények és eljárások toxigenicitás meghatározására |
| PL3014267T3 (pl) * | 2013-06-28 | 2019-05-31 | Merz Pharma Gmbh & Co Kgaa | Środki i sposoby określania aktywności biologicznej polipeptydów neurotoksyny w komórkach |
| US9480731B2 (en) * | 2013-12-12 | 2016-11-01 | Medy-Tox, Inc. | Long lasting effect of new botulinum toxin formulations |
| SG11202005239YA (en) * | 2017-12-04 | 2020-07-29 | Revance Therapeutics Inc | Injectable botulinum toxin formulations and methods of use thereof having high response rate and long effect duration |
| IL298399A (en) | 2020-06-05 | 2023-01-01 | Merz Pharma Gmbh & Co Kgaa | Treatment of facial wrinkles with the botulinum toxin in high dose and low volume |
-
2021
- 2021-06-04 IL IL298399A patent/IL298399A/en unknown
- 2021-06-04 US US18/007,712 patent/US12599550B2/en active Active
- 2021-06-04 EP EP21728601.2A patent/EP4161562B1/en active Active
- 2021-06-04 KR KR1020227040449A patent/KR20230020961A/ko active Pending
- 2021-06-04 ES ES21728601T patent/ES3013130T3/es active Active
- 2021-06-04 TW TW110120421A patent/TW202214211A/zh unknown
- 2021-06-04 JP JP2022573504A patent/JP2023529095A/ja active Pending
- 2021-06-04 AU AU2021286196A patent/AU2021286196A1/en active Pending
- 2021-06-04 CA CA3177835A patent/CA3177835A1/en active Pending
- 2021-06-04 CN CN202180037805.1A patent/CN115666629A/zh active Pending
- 2021-06-04 BR BR112022023413A patent/BR112022023413A2/pt unknown
- 2021-06-04 EP EP24206746.0A patent/EP4467202A3/en active Pending
- 2021-06-04 MX MX2022014564A patent/MX2022014564A/es unknown
- 2021-06-04 WO PCT/EP2021/064986 patent/WO2021245223A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| JP2023529095A (ja) | 2023-07-07 |
| CN115666629A (zh) | 2023-01-31 |
| EP4161562A1 (en) | 2023-04-12 |
| MX2022014564A (es) | 2022-12-15 |
| EP4467202A3 (en) | 2025-02-19 |
| WO2021245223A1 (en) | 2021-12-09 |
| EP4161562B1 (en) | 2024-11-20 |
| AU2021286196A1 (en) | 2022-12-01 |
| KR20230020961A (ko) | 2023-02-13 |
| EP4467202A2 (en) | 2024-11-27 |
| ES3013130T3 (en) | 2025-04-11 |
| TW202214211A (zh) | 2022-04-16 |
| IL298399A (en) | 2023-01-01 |
| CA3177835A1 (en) | 2021-12-09 |
| US20230329996A1 (en) | 2023-10-19 |
| US12599550B2 (en) | 2026-04-14 |
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