BR112022021745A2 - Revestimento conformal de células para imunoisolamento - Google Patents
Revestimento conformal de células para imunoisolamentoInfo
- Publication number
- BR112022021745A2 BR112022021745A2 BR112022021745A BR112022021745A BR112022021745A2 BR 112022021745 A2 BR112022021745 A2 BR 112022021745A2 BR 112022021745 A BR112022021745 A BR 112022021745A BR 112022021745 A BR112022021745 A BR 112022021745A BR 112022021745 A2 BR112022021745 A2 BR 112022021745A2
- Authority
- BR
- Brazil
- Prior art keywords
- immunoisolation
- coating
- conformal
- cell coating
- methods
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/022—Artificial gland structures using bioreactors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
- A61K35/39—Pancreas; Islets of Langerhans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
- C08L71/02—Polyalkylene oxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/64—Animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2420/00—Materials or methods for coatings medical devices
- A61L2420/02—Methods for coating medical devices
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Transplantation (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cell Biology (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Botany (AREA)
- Heart & Thoracic Surgery (AREA)
- Virology (AREA)
- Vascular Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Biotechnology (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Pharmacology & Pharmacy (AREA)
- Cardiology (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Materials For Medical Uses (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
REVESTIMENTO CONFORMAL DE CÉLULAS PARA IMUNOISOLAMENTO. A presente invenção refere-se a métodos hidrodinâmicos para revestir de maneira conformal as células de tamanho não uniforme e aglomerados de células com biomateriais para implantação, evitando assim rejeição imune ou inflamação ou destruição autoimune, embora preservando funcionalidade celular. São ainda descritos reagentes, aparelho e métodos para revestir de maneira conformal células e aglomerados de células com hidrogéis que são biocompatíveis, mecanicamente e quimicamente estáveis e porosos, com um tamanho de corte de poro apropriado.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US202063016787P | 2020-04-28 | 2020-04-28 | |
PCT/US2021/029744 WO2021222469A1 (en) | 2020-04-28 | 2021-04-28 | Conformal coating of cells for immunoisolation |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112022021745A2 true BR112022021745A2 (pt) | 2022-12-06 |
Family
ID=76035128
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112022021745A BR112022021745A2 (pt) | 2020-04-28 | 2021-04-28 | Revestimento conformal de células para imunoisolamento |
Country Status (11)
Country | Link |
---|---|
US (1) | US20230165669A1 (pt) |
EP (1) | EP4142646A1 (pt) |
JP (1) | JP2023524442A (pt) |
KR (1) | KR20230021653A (pt) |
CN (1) | CN115916112A (pt) |
AU (1) | AU2021263388A1 (pt) |
BR (1) | BR112022021745A2 (pt) |
CA (1) | CA3181359A1 (pt) |
IL (1) | IL297648A (pt) |
MX (1) | MX2022013591A (pt) |
WO (1) | WO2021222469A1 (pt) |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5529914A (en) | 1990-10-15 | 1996-06-25 | The Board Of Regents The Univeristy Of Texas System | Gels for encapsulation of biological materials |
US5334640A (en) * | 1992-04-08 | 1994-08-02 | Clover Consolidated, Ltd. | Ionically covalently crosslinked and crosslinkable biocompatible encapsulation compositions and methods |
SK285392B6 (sk) | 1998-12-15 | 2006-12-07 | Universidad Nacional Autonoma De M�Xico | Zariadenie na uľahčenie implantácie biologického materiálu a/alebo tvorbu materiálu na tkanivové implantáty |
JP4560545B2 (ja) | 2004-07-29 | 2010-10-13 | ユニバーシティ オブ マイアミ | 細胞治療のためのハイブリッドデバイス |
ES2637640T3 (es) | 2011-04-29 | 2017-10-16 | Converge Biotech Inc. | Recubrimiento conformal de células para inmunoaislamiento |
US9381217B2 (en) * | 2013-09-09 | 2016-07-05 | Georgia Tech Research Corporation | Microgels for encapsulation of cells and other biologic agents |
-
2021
- 2021-04-28 EP EP21727031.3A patent/EP4142646A1/en active Pending
- 2021-04-28 CN CN202180037313.2A patent/CN115916112A/zh active Pending
- 2021-04-28 WO PCT/US2021/029744 patent/WO2021222469A1/en unknown
- 2021-04-28 JP JP2022565798A patent/JP2023524442A/ja active Pending
- 2021-04-28 KR KR1020227041729A patent/KR20230021653A/ko active Search and Examination
- 2021-04-28 CA CA3181359A patent/CA3181359A1/en active Pending
- 2021-04-28 MX MX2022013591A patent/MX2022013591A/es unknown
- 2021-04-28 AU AU2021263388A patent/AU2021263388A1/en active Pending
- 2021-04-28 IL IL297648A patent/IL297648A/en unknown
- 2021-04-28 BR BR112022021745A patent/BR112022021745A2/pt unknown
- 2021-04-28 US US17/921,888 patent/US20230165669A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
MX2022013591A (es) | 2023-03-06 |
IL297648A (en) | 2022-12-01 |
US20230165669A1 (en) | 2023-06-01 |
AU2021263388A1 (en) | 2023-01-05 |
EP4142646A1 (en) | 2023-03-08 |
WO2021222469A1 (en) | 2021-11-04 |
CN115916112A (zh) | 2023-04-04 |
CA3181359A1 (en) | 2021-11-04 |
KR20230021653A (ko) | 2023-02-14 |
JP2023524442A (ja) | 2023-06-12 |
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