BR112022020929A2 - Complexo aniônico bicoordenado de prata, sais do mesmo, soluções, composições de ácido hialurônico e pó feito de partículas de sílica - Google Patents

Complexo aniônico bicoordenado de prata, sais do mesmo, soluções, composições de ácido hialurônico e pó feito de partículas de sílica

Info

Publication number
BR112022020929A2
BR112022020929A2 BR112022020929A BR112022020929A BR112022020929A2 BR 112022020929 A2 BR112022020929 A2 BR 112022020929A2 BR 112022020929 A BR112022020929 A BR 112022020929A BR 112022020929 A BR112022020929 A BR 112022020929A BR 112022020929 A2 BR112022020929 A2 BR 112022020929A2
Authority
BR
Brazil
Prior art keywords
silver
complex
anionic
bicoordinated
antimicrobial
Prior art date
Application number
BR112022020929A
Other languages
English (en)
Inventor
Alberto Bignozzi Carlo
Jozef Quint Bertus
COGO Alberto
Original Assignee
Penta Science Ind Holding B V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Penta Science Ind Holding B V filed Critical Penta Science Ind Holding B V
Publication of BR112022020929A2 publication Critical patent/BR112022020929A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/38—Silver; Compounds thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
    • A01N59/16—Heavy metals; Compounds thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
    • A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/30—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests characterised by the surfactants
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
    • A01P1/00—Disinfectants; Antimicrobial compounds or mixtures thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Pest Control & Pesticides (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Oncology (AREA)
  • Emergency Medicine (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

COMPLEXO ANIÔNICO BICOORDENADO DE PRATA, SAIS DO MESMO, SOLUÇÕES, COMPOSIÇÕES DE ÁCIDO HIALURÔNICO E PÓ FEITO DE PARTÍCULAS DE SÍLICA. Um complexo de prata (I) bicoordenado aniônico tem atividade antimicrobiana e a fórmula geral [Ag+(L2-)2]3-, em que L2- é um ligante selecionado a partir do grupo consistindo em acetato de 2-mercapto-4-metil-5-tiazol, 3-mercapto-1-propansulfonato, sulfonato de 2-mercapto-5-benzimidazol e tiosalicilato. Um sal de sódio do supracitado complexo de prata (I) bicoordenado aniônico tem atividade antimicrobiana e a fórmula geral Na+3[Ag+(L2-)2]3-. Um sal do supracitado complexo de prata (I) bicoordenado aniônico tem atividade antimicrobiana e a fórmula geral (W+)3[Ag+(L2-)2]n, em que W+ é um agente tensoativo catiônico selecionado a partir do grupo consistindo em octenidina, clorexidina, benzalcônio e didecildimetilamônio; n é 2 quando W+ é octenidina ou clorexidina; n é 1 quando W+ é benzalcônio ou didecildimetilamônio. O complexo de prata (I) bicoordenado aniônico pode ser incorporado em um gel antimicrobiano contendo hialuronato de sódio e ascorbil fosfato de sódio. O gel antimicrobiano é termicamente e fotoquimicamente estável e é adequado para uso médico; em particular, pode ser usado como um curativo líquido. Os sais contendo complexos apresentam alta afinidade por superfícies sólidas e podem ser adsorvidos em superfícies sólidas, permitindo assim formular revestimentos e pós antimicrobianos.
BR112022020929A 2020-04-16 2020-04-16 Complexo aniônico bicoordenado de prata, sais do mesmo, soluções, composições de ácido hialurônico e pó feito de partículas de sílica BR112022020929A2 (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2020/060686 WO2021209134A1 (en) 2020-04-16 2020-04-16 Antimicrobial silver coordination complexes

Publications (1)

Publication Number Publication Date
BR112022020929A2 true BR112022020929A2 (pt) 2022-12-27

Family

ID=70333938

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112022020929A BR112022020929A2 (pt) 2020-04-16 2020-04-16 Complexo aniônico bicoordenado de prata, sais do mesmo, soluções, composições de ácido hialurônico e pó feito de partículas de sílica

Country Status (7)

Country Link
US (1) US20230240302A1 (pt)
EP (1) EP4135723A1 (pt)
JP (1) JP2023530387A (pt)
BR (1) BR112022020929A2 (pt)
CA (1) CA3175688A1 (pt)
MX (1) MX2022012999A (pt)
WO (1) WO2021209134A1 (pt)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2408206B (en) * 2003-11-18 2007-11-28 Johnson & Johnson Medical Ltd Antioxidant and antimicrobial wound dressing materials
IT201800000576A1 (it) * 2018-01-05 2019-07-05 Lab Srl Complessi di coordinazione aventi attività antimicrobica e incorporabili in composizioni di acido ialuronico

Also Published As

Publication number Publication date
JP2023530387A (ja) 2023-07-18
EP4135723A1 (en) 2023-02-22
WO2021209134A1 (en) 2021-10-21
CA3175688A1 (en) 2021-10-21
MX2022012999A (es) 2023-01-24
US20230240302A1 (en) 2023-08-03

Similar Documents

Publication Publication Date Title
US3751562A (en) Medicated gelled oils
EP1769824B1 (en) Quick-drying disinfectant gel for hands
AU703926B2 (en) Composition for inactivating irritants in fluids
US5334388A (en) Antimicrobial drying substrate
JPH0597602A (ja) 抗菌性組成物
CN105482536A (zh) 一种透明抗菌亲水涂料
BR9814570A (pt) Composição biostática e revestimento para reduzir e evitar aderência bacteriana e microbiana, e, processo para preparar um artigo biostático.
TWI650308B (zh) 有機矽烷水溶液及其保存方法
BR112022020929A2 (pt) Complexo aniônico bicoordenado de prata, sais do mesmo, soluções, composições de ácido hialurônico e pó feito de partículas de sílica
CN104069024B (zh) 一种增稠剂组合物及其在化妆品中的应用
JP2010163429A (ja) バイオフィルム生成抑制方法
CN108184898A (zh) 一种无机复合抗菌剂的制备方法
CN113456671B (zh) 一种友好型持久抗菌消毒凝胶及其制备方法
CL2022002865A1 (es) Complejos antimicrobianos de coordinación de plata
CN105473123A (zh) 低醇含量消毒泡沫
CN105532731A (zh) 一种缓释型膦酸锆载银抗菌剂的制备方法
US2977278A (en) Anionic-carrier iodine compositions for controlling microorganisms
CN104069023B (zh) 一种增稠剂组合物及其在化妆品中的应用
CN111184658A (zh) 一种手部消毒液及其制备方法
JPS6328403B2 (pt)
CN113455517B (zh) 一种环境友好型缓释抗菌消毒乳液及其制备方法
BR0101302A (pt) Formulação pesticida sólida
CN112063251A (zh) 一种用于妇检鸭嘴扩张器涂层制剂
BR9815836A (pt) Composições de ciclodextrina descomplexada aperfeiçoada para controle de odor
BR9908143A (pt) Composições para a redução da atividade enzimática, utilização de ácido dissuccìnico de etileno diamina, utilização de um agente de complexação, artigo absorvente, desodorante, e utilização de composição