BR112022017973A2 - Imunização de reforço ativa contra tétano, difteria e coqueluche - Google Patents

Imunização de reforço ativa contra tétano, difteria e coqueluche

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Publication number
BR112022017973A2
BR112022017973A2 BR112022017973A BR112022017973A BR112022017973A2 BR 112022017973 A2 BR112022017973 A2 BR 112022017973A2 BR 112022017973 A BR112022017973 A BR 112022017973A BR 112022017973 A BR112022017973 A BR 112022017973A BR 112022017973 A2 BR112022017973 A2 BR 112022017973A2
Authority
BR
Brazil
Prior art keywords
diphtheria
immunization against
against tetanus
wholesome
boost immunization
Prior art date
Application number
BR112022017973A
Other languages
English (en)
Inventor
d campbell John
L Coffman Robert
N Hyer Randall
S Janssen Robert
Novack David
Gohlke Martin
Urban Maureen
Gairola Sunil
Shaligram Umesh
Gautum Manish
Rao Harish
Original Assignee
Dynavax Tech Corp
Serum Institute Of India Pvt Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dynavax Tech Corp, Serum Institute Of India Pvt Ltd filed Critical Dynavax Tech Corp
Publication of BR112022017973A2 publication Critical patent/BR112022017973A2/pt

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0016—Combination vaccines based on diphtheria-tetanus-pertussis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/08—Clostridium, e.g. Clostridium tetani
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/05—Actinobacteria, e.g. Actinomyces, Streptomyces, Nocardia, Bifidobacterium, Gardnerella, Corynebacterium; Propionibacterium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/099—Bordetella
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/125—Picornaviridae, e.g. calicivirus
    • A61K39/13—Poliovirus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P37/02—Immunomodulators
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/117—Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • C—CHEMISTRY; METALLURGY
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    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

IMUNIZAÇÃO DE REFORÇO ATIVA CONTRA TÉTANO, DIFTERIA E COQUELUCHE. A presente invenção refere-se a composições imunogênicas compreendendo antígenos de tétano, difteria e coqueluche acelular (Tdap), e um agonista do receptor 9 do tipo toll (TLR9), tal como oligonucleotídeo compreendendo um motivo de citidina-fosfo-guanosina (CpG) não metilado. As composições imunogênicas podem ainda compreender um adjuvante sal de alumínio ao qual os antígenos de Tdap são adsorvidos. As composições imunogênicas são adequadas para imunização de reforço ativa contra tétano, difteria e coqueluche em um indivíduo em necessidade das mesmas.
BR112022017973A 2020-03-09 2021-03-09 Imunização de reforço ativa contra tétano, difteria e coqueluche BR112022017973A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN202011010025 2020-03-09
IN202011055399 2020-12-19
PCT/US2021/021532 WO2021183533A1 (en) 2020-03-09 2021-03-09 Active booster immunization against tetanus, diphtheria and pertussis

Publications (1)

Publication Number Publication Date
BR112022017973A2 true BR112022017973A2 (pt) 2022-11-16

Family

ID=77672117

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112022017973A BR112022017973A2 (pt) 2020-03-09 2021-03-09 Imunização de reforço ativa contra tétano, difteria e coqueluche

Country Status (12)

Country Link
US (1) US20230072809A1 (pt)
EP (1) EP4117719A4 (pt)
JP (1) JP2023517330A (pt)
KR (1) KR20230011916A (pt)
CN (1) CN115697389A (pt)
AU (1) AU2021236055A1 (pt)
BR (1) BR112022017973A2 (pt)
CA (1) CA3174987A1 (pt)
CL (1) CL2022002456A1 (pt)
IL (1) IL296286A (pt)
MX (1) MX2022011155A (pt)
WO (1) WO2021183533A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115554395A (zh) * 2022-10-12 2023-01-03 长春百克生物科技股份公司 一种百白破复合佐剂联合疫苗

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060014713A1 (en) * 2004-06-15 2006-01-19 Hybridon, Inc. Immunostimulatory oligonucleotide multimers
EP1979488A4 (en) * 2006-01-09 2009-05-27 Univ California IMMUNOSTIMULATORY COMBINATIONS OF TNFRSF, TLR, NLR, RHR, PURINERGIC RECEPTOR AND CYTOKINE RECEPTOR AGONISTS USED FOR VACCINES AND ANTI-TUMOR IMMUNOTHERAPY
US9254327B2 (en) * 2010-05-10 2016-02-09 Alnylam Pharmaceuticals, Inc. Methods and compositions for delivery of active agents
US9452212B2 (en) * 2011-04-14 2016-09-27 Dynavax Technologies Corporation Methods and compositions for eliciting an immune response against hepatitis B virus
DK2863943T3 (en) * 2013-03-08 2016-11-07 Janssen Vaccines & Prevention Bv acellular pertussis vaccines
AU2014304545A1 (en) * 2013-08-05 2016-02-25 Glaxosmithkline Biologicals S.A. Combination immunogenic compositions
CN113395977A (zh) * 2018-12-05 2021-09-14 圣诺菲·帕斯图尔公司 百日咳加强疫苗

Also Published As

Publication number Publication date
CN115697389A (zh) 2023-02-03
EP4117719A4 (en) 2024-05-22
WO2021183533A1 (en) 2021-09-16
AU2021236055A1 (en) 2022-10-20
US20230072809A1 (en) 2023-03-09
CL2022002456A1 (es) 2023-06-23
CA3174987A1 (en) 2021-09-16
JP2023517330A (ja) 2023-04-25
IL296286A (en) 2022-11-01
KR20230011916A (ko) 2023-01-25
MX2022011155A (es) 2023-01-04
EP4117719A1 (en) 2023-01-18

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