BR0111834A - Composições adjuvante e imunogênica, e, método para eliciar uma resposta imune a um antìgeno - Google Patents
Composições adjuvante e imunogênica, e, método para eliciar uma resposta imune a um antìgenoInfo
- Publication number
- BR0111834A BR0111834A BR0111834-0A BR0111834A BR0111834A BR 0111834 A BR0111834 A BR 0111834A BR 0111834 A BR0111834 A BR 0111834A BR 0111834 A BR0111834 A BR 0111834A
- Authority
- BR
- Brazil
- Prior art keywords
- adjuvant
- antigen
- compositions
- disclosed
- eliciting
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/208—IL-12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
- A61K2039/55527—Interleukins
- A61K2039/55538—IL-12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
"COMPOSIçõES ADJUVANTE E IMUNOGêNICA, E, MéTODO PARA ELICIAR UMA RESPOSTA IMUNE A UM ANTìGENO". Composições adjuvantes que compreendem uma quantidade eficaz de IL-12 e QS-21 são divulgadas. Composições imunogênicas, de vacina e farmacêuticas que compreendem uma mistura de antígeno e uma composição adjuvante que compreende uma quantidade eficaz de IL-12 e QS-21 também são divulgadas. Estas composições eliciam respostas imunes mediadas por célula e humoral funcionais contra pelo menos um antígeno. Métodos de usar as composições divulgadas também são divulgados.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US21314300P | 2000-06-22 | 2000-06-22 | |
PCT/US2001/019805 WO2001097841A2 (en) | 2000-06-22 | 2001-06-21 | Qs-21 and il-12 as an adjuvant combination |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0111834A true BR0111834A (pt) | 2003-07-08 |
Family
ID=22793897
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0111834-0A BR0111834A (pt) | 2000-06-22 | 2001-06-21 | Composições adjuvante e imunogênica, e, método para eliciar uma resposta imune a um antìgeno |
Country Status (11)
Country | Link |
---|---|
US (1) | US7374751B1 (pt) |
EP (1) | EP1305044A2 (pt) |
JP (1) | JP2003535906A (pt) |
KR (2) | KR20030015288A (pt) |
CN (1) | CN1437481A (pt) |
AU (2) | AU2001270031B2 (pt) |
BR (1) | BR0111834A (pt) |
CA (1) | CA2409406C (pt) |
IL (1) | IL153133A0 (pt) |
MX (1) | MXPA02011737A (pt) |
WO (1) | WO2001097841A2 (pt) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070154399A1 (en) * | 2000-10-27 | 2007-07-05 | Hadden John W | Immunotherapy for immune suppressed patients |
US6977072B2 (en) | 2000-10-27 | 2005-12-20 | Irx Therapeutics, Inc. | Vaccine immunotherapy for immune suppressed patients |
US20070025958A1 (en) | 2000-10-27 | 2007-02-01 | Hadden John W | Vaccine immunotherapy |
US7727561B2 (en) * | 2001-08-31 | 2010-06-01 | Pacific Arrow Limited | Composition comprising Xanthoceras sorbifolia extracts, compounds isolated from same, methods for preparing same and uses thereof |
US7524824B2 (en) * | 2003-09-04 | 2009-04-28 | Pacific Arrow Limited | Composition comprising Xanthoceras sorbifolia extracts, compounds isolated from same, methods for preparing same and uses thereof |
US7514412B2 (en) * | 2003-10-09 | 2009-04-07 | Pacific Arrow Limited | Anticancer biangeloyl saponins |
US8614197B2 (en) * | 2003-10-09 | 2013-12-24 | Pacific Arrow Limited | Anti-tumor compounds with angeloyl groups |
US7488753B2 (en) * | 2003-10-09 | 2009-02-10 | Pacific Arrow Limited | Composition comprising triterpene saponins and compounds with angeloyl functional group, methods for preparing same and uses thereof |
JP4815558B2 (ja) * | 2003-10-09 | 2011-11-16 | パシフィック アロー リミテッド | Xanthocerassorbifolia抽出物を含む組成物、該抽出物から単離された化合物、それらを調製する方法、およびそれらの使用 |
US8735558B2 (en) * | 2005-02-14 | 2014-05-27 | Pacific Arrow Limited | Blocking the migration or metastasis of cancer cells by affecting adhesion proteins and the uses of new compounds thereof |
US9382285B2 (en) | 2004-09-07 | 2016-07-05 | Pacific Arrow Limited | Methods and compounds for modulating the secretion or expression of adhesion proteins or angiopoietins of cells |
US8586719B2 (en) * | 2005-04-27 | 2013-11-19 | Pacific Arrow Limited | Triterpenes for modulating gene expression and cell membrane, and as antiprotozoal agents |
EP1982726A1 (en) * | 2006-02-07 | 2008-10-22 | Nippon Biologicals, Inc. | Novel vaccine carrier |
JP5797190B2 (ja) | 2009-05-15 | 2015-10-21 | アイ アール エックス セーラピューティクス, インコーポレイテッド | ワクチン免疫療法 |
US9434677B2 (en) | 2009-07-16 | 2016-09-06 | Pacific Arrow Limited | Natural and synthetic compounds for treating cancer and other diseases |
US20120277308A1 (en) | 2010-07-16 | 2012-11-01 | Pacific Arrow Limited | compounds for treating cancer and other diseases |
US9499577B2 (en) | 2009-07-16 | 2016-11-22 | Pacific Arrow Limited | Natural and synthetic compounds for treating cancer and other diseases |
AU2010328197B2 (en) | 2009-12-08 | 2015-07-16 | Irx Therapeutics, Inc. | Method of reversing immune suppression of Langerhans cells |
WO2014064534A2 (en) | 2012-10-05 | 2014-05-01 | Chrontech Pharma Ab | Injection needle, device, immunogenic compositions and method of use |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5057540A (en) * | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
US4912094B1 (en) * | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
PT705109E (pt) * | 1993-05-25 | 2001-02-28 | American Cyanamid Co | Adjuvantes para vacinas contra virus sinciciais respiratorios |
WO1996010423A1 (en) * | 1994-09-30 | 1996-04-11 | Ludwig Institute For Cancer Research | COMPOSITIONS CONTAINING A p53 DERIVED PROTEIN OR PEPTIDE, AN ADJUVANT, AND INTERLEUKIN-12 AND USES THEREOF |
MX9702396A (es) * | 1994-10-05 | 1997-12-31 | Univ Vanderbilt | Interleukina-12 como adyuvante para vacunas de paramyxoviridae. |
AU6024596A (en) * | 1995-05-23 | 1996-12-11 | Regents Of The University Of California, The | Abundant extracellular products and methods for their production and use |
EP1649868A1 (en) * | 1996-05-31 | 2006-04-26 | National University of Ireland, Maynooth | IL-12 as an adjuvant for Bordetella pertussis vaccines |
ATE382368T1 (de) * | 1997-01-21 | 2008-01-15 | Univ California | Epitopen eines extrazellulären antigens |
GB9712347D0 (en) * | 1997-06-14 | 1997-08-13 | Smithkline Beecham Biolog | Vaccine |
IS4518A (is) * | 1997-07-09 | 1999-01-10 | Lyfjathroun Hf, The Icelandic Bio Pharmaceutical Group | Nýtt lyfjaform fyrir bóluefni |
WO2000009140A1 (en) * | 1997-07-24 | 2000-02-24 | Thomas Jefferson University | Composition and method of using tumor cells |
EP1053016A2 (en) * | 1998-02-12 | 2000-11-22 | American Cyanamid Company | Vaccines comprising interleukin-12 and respiratory syncytial viral antigens |
-
2001
- 2001-06-21 AU AU2001270031A patent/AU2001270031B2/en not_active Ceased
- 2001-06-21 WO PCT/US2001/019805 patent/WO2001097841A2/en active IP Right Grant
- 2001-06-21 KR KR1020027017426A patent/KR20030015288A/ko not_active Application Discontinuation
- 2001-06-21 IL IL15313301A patent/IL153133A0/xx not_active IP Right Cessation
- 2001-06-21 CA CA2409406A patent/CA2409406C/en not_active Expired - Fee Related
- 2001-06-21 KR KR1020087006466A patent/KR20080027973A/ko active Search and Examination
- 2001-06-21 US US10/311,422 patent/US7374751B1/en not_active Expired - Fee Related
- 2001-06-21 AU AU7003101A patent/AU7003101A/xx active Pending
- 2001-06-21 CN CN01811650A patent/CN1437481A/zh active Pending
- 2001-06-21 MX MXPA02011737A patent/MXPA02011737A/es active IP Right Grant
- 2001-06-21 EP EP01948561A patent/EP1305044A2/en not_active Withdrawn
- 2001-06-21 JP JP2002503325A patent/JP2003535906A/ja active Pending
- 2001-06-21 BR BR0111834-0A patent/BR0111834A/pt not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU2001270031B2 (en) | 2005-11-03 |
IL153133A0 (en) | 2003-06-24 |
CA2409406C (en) | 2010-09-14 |
MXPA02011737A (es) | 2003-03-27 |
WO2001097841A3 (en) | 2002-05-30 |
WO2001097841A2 (en) | 2001-12-27 |
JP2003535906A (ja) | 2003-12-02 |
US20080112925A1 (en) | 2008-05-15 |
CN1437481A (zh) | 2003-08-20 |
CA2409406A1 (en) | 2001-12-27 |
KR20030015288A (ko) | 2003-02-20 |
KR20080027973A (ko) | 2008-03-28 |
US7374751B1 (en) | 2008-05-20 |
EP1305044A2 (en) | 2003-05-02 |
AU7003101A (en) | 2002-01-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25D | Requested change of name of applicant approved | ||
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O, 11, 13, 25 E 6 DA LPI. |
|
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |