BR112022017797A2 - Métodos de distribuição de um bacteriófago, de tratamento de uma infecção bacteriana, de isolamento de um fago direcionado a uma bactéria e composição - Google Patents

Métodos de distribuição de um bacteriófago, de tratamento de uma infecção bacteriana, de isolamento de um fago direcionado a uma bactéria e composição

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Publication number
BR112022017797A2
BR112022017797A2 BR112022017797A BR112022017797A BR112022017797A2 BR 112022017797 A2 BR112022017797 A2 BR 112022017797A2 BR 112022017797 A BR112022017797 A BR 112022017797A BR 112022017797 A BR112022017797 A BR 112022017797A BR 112022017797 A2 BR112022017797 A2 BR 112022017797A2
Authority
BR
Brazil
Prior art keywords
methods
bacteriophage
bacteria
isolation
distribution
Prior art date
Application number
BR112022017797A
Other languages
English (en)
Inventor
Holder Jason
P Magnant Gary
Original Assignee
Endolytix Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Endolytix Tech Inc filed Critical Endolytix Tech Inc
Publication of BR112022017797A2 publication Critical patent/BR112022017797A2/pt

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    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
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    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
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Abstract

MÉTODOS DE DISTRIBUIÇÃO DE UM BACTERIÓFAGO, DE TRATAMENTO DE UMA INFECÇÃO BACTERIANA, DE ISOLAMENTO DE UM FAGO DIRECIONADO A UMA BACTÉRIA E COMPOSIÇÃO. A presente divulgação apresenta composições e métodos para o tratamento de infecções bacterianas, tais como infecções bacterianas causadas por células bacterianas que residem em uma célula hospedeira (por exemplo, uma célula de mamífero, por exemplo, célula imunológica, por exemplo, macrófago ou célula dendrítica). As composições e os métodos incluem a distribuição de um bacteriófago e uma proteína lítica antibacteriana para o compartimento intracelular (endossoma, fagossoma, lisossoma ou citosol) no qual a célula bacteriana reside.
BR112022017797A 2020-03-06 2021-03-08 Métodos de distribuição de um bacteriófago, de tratamento de uma infecção bacteriana, de isolamento de um fago direcionado a uma bactéria e composição BR112022017797A2 (pt)

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