BR112022013991A2 - Formulação para tratar uma doença ou distúrbio tratável por um agonista do receptor de adenosina a3 (a3ar), canabinoide, método de tratamento de uma doença ou distúrbio tratável por um agonista do receptor de adenosina a3 (a3ar) e método de tratamento de uma doença ou distúrbio em um sujeito - Google Patents
Formulação para tratar uma doença ou distúrbio tratável por um agonista do receptor de adenosina a3 (a3ar), canabinoide, método de tratamento de uma doença ou distúrbio tratável por um agonista do receptor de adenosina a3 (a3ar) e método de tratamento de uma doença ou distúrbio em um sujeitoInfo
- Publication number
- BR112022013991A2 BR112022013991A2 BR112022013991A BR112022013991A BR112022013991A2 BR 112022013991 A2 BR112022013991 A2 BR 112022013991A2 BR 112022013991 A BR112022013991 A BR 112022013991A BR 112022013991 A BR112022013991 A BR 112022013991A BR 112022013991 A2 BR112022013991 A2 BR 112022013991A2
- Authority
- BR
- Brazil
- Prior art keywords
- disease
- treatment
- a3ar
- adenosine
- disorder
- Prior art date
Links
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 14
- 108010060261 Adenosine A3 Receptor Proteins 0.000 title abstract 10
- 102000008161 Adenosine A3 Receptor Human genes 0.000 title abstract 10
- 201000010099 disease Diseases 0.000 title abstract 7
- 239000000556 agonist Substances 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 4
- 238000009472 formulation Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 229930003827 cannabinoid Natural products 0.000 abstract 2
- 239000003557 cannabinoid Substances 0.000 abstract 2
- 229940065144 cannabinoids Drugs 0.000 abstract 2
- 101150046889 ADORA3 gene Proteins 0.000 abstract 1
- 239000012190 activator Substances 0.000 abstract 1
- 230000002149 cannabinoid effect Effects 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 240000004308 marijuana Species 0.000 abstract 1
- 239000000419 plant extract Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/658—Medicinal preparations containing organic active ingredients o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Mycology (AREA)
- Diabetes (AREA)
- Microbiology (AREA)
- Obesity (AREA)
- Botany (AREA)
- Hematology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
FORMULAÇÃO PARA TRATAR UMA DOENÇA OU DISTÚRBIO TRATÁVEL POR UM AGONISTA DO RECEPTOR DE ADENOSINA A3 (A3AR), CANABINOIDE, MÉTODO DE TRATAMENTO DE UMA DOENÇA OU DISTÚRBIO TRATÁVEL POR UM AGONISTA DO RECEPTOR DE ADENOSINA A3 (A3AR) E MÉTODO DE TRATAMENTO DE UMA DOENÇA OU DISTÚRBIO EM UM SUJEITO. Trata-se de canabinoides usados para tratar doenças ou distúrbios tratáveis por um ativador do receptor de adenosina A3 (A3AR). O efeito do canabinoide é exercido através do A3AR. Os canabinoides podem ser selecionados a partir de fitocanabinoides naturais, derivados sintéticos de fitocanabinoides, extratos da planta cannabis e outros.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL272078A IL272078A (en) | 2020-01-16 | 2020-01-16 | Cannabinoids for use in therapy |
PCT/IL2021/050046 WO2021144799A1 (en) | 2020-01-16 | 2021-01-14 | Cannabinoids for use in treatment |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112022013991A2 true BR112022013991A2 (pt) | 2022-10-11 |
Family
ID=76863896
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112022013991A BR112022013991A2 (pt) | 2020-01-16 | 2021-01-14 | Formulação para tratar uma doença ou distúrbio tratável por um agonista do receptor de adenosina a3 (a3ar), canabinoide, método de tratamento de uma doença ou distúrbio tratável por um agonista do receptor de adenosina a3 (a3ar) e método de tratamento de uma doença ou distúrbio em um sujeito |
Country Status (11)
Country | Link |
---|---|
US (1) | US20230049415A1 (pt) |
EP (1) | EP4090324A1 (pt) |
JP (1) | JP2023510003A (pt) |
KR (1) | KR20220137661A (pt) |
CN (1) | CN114980873A (pt) |
AU (1) | AU2021207766A1 (pt) |
BR (1) | BR112022013991A2 (pt) |
CA (1) | CA3164880A1 (pt) |
IL (1) | IL272078A (pt) |
MX (1) | MX2022008850A (pt) |
WO (1) | WO2021144799A1 (pt) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA3229494A1 (en) * | 2021-08-19 | 2023-02-23 | Yun Kau Tam | A pharmaceutical platform technology for drug discovery and consumer health product development |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6790839B2 (en) | 1999-01-07 | 2004-09-14 | Can-Fite Biopharma Ltd. | Pharmaceutical administration of adenosine agonists |
ATE292973T1 (de) | 2001-01-16 | 2005-04-15 | Can Fite Biopharma Ltd | Verwendung eines adenosin-a3-rezeptor-agonisten zur hemmung der virenreplikation |
AU2003274648A1 (en) * | 2002-10-22 | 2004-05-13 | Can-Fite Biopharma Ltd. | The use of the a3 adenosine receptor as a marker for a diseased state |
WO2004045627A1 (en) | 2002-11-19 | 2004-06-03 | Can-Fite Biopharma Ltd. | A3ar agonists for the treatment of inflammatory arthritis |
US7320805B2 (en) * | 2003-10-01 | 2008-01-22 | Institut National De La Sante Et De La Recherche Medicale | CB2 receptors blocks accumulation of human hepatic myofibroblasts: a novel artifibrogenic pathway in the liver |
AU2006321165B2 (en) | 2005-11-30 | 2010-04-22 | Can-Fite Biopharma Ltd. | Use of A3 adenosine receptor agonist in osteoarthritis treatment |
MX2007010896A (es) * | 2007-09-06 | 2009-03-06 | Univ Mexico Nacional Autonoma | Uso de sales de adenosina para la preparacion de productos farmaceuticos para el tratamiento del cancer. |
EP2227234B1 (en) | 2007-10-15 | 2014-05-07 | Can-Fite Biopharma Ltd. | Method for inducing hepatocyte proliferation and uses thereof |
GB2459637B (en) | 2008-01-21 | 2012-06-06 | Gw Pharma Ltd | New use for cannabinoids |
GB2471987B (en) * | 2008-06-04 | 2012-02-22 | Gw Pharma Ltd | Anti-tumoural effects of cannabinoid combinations |
IL200753A (en) | 2009-09-06 | 2015-06-30 | Can Fite Biopharma Ltd | Pharmaceutical preparation containing ib – meca for the treatment of psoriasis |
GB2494461A (en) * | 2011-09-12 | 2013-03-13 | Gw Pharma Ltd | Phytocannabinoids for use in the treatment of invasive cancers or metastases |
US20130169785A1 (en) * | 2011-12-30 | 2013-07-04 | Agco Corporation | Method of detecting and improving operator situational awareness on agricultural machines |
EP2806878A1 (en) | 2012-01-23 | 2014-12-03 | Can-Fite Biopharma Ltd. | Treatment of liver conditions |
GB2515312A (en) * | 2013-06-19 | 2014-12-24 | Gw Pharma Ltd | The use of phytocannabinoids in the treatment of ovarian carcinoma |
GB2527590A (en) * | 2014-06-27 | 2015-12-30 | Otsuka Pharma Co Ltd | Active pharmaceutical ingredient (API) comprising cannabinoids for use in the treatment of cancer |
IL242723B (en) | 2015-11-23 | 2019-12-31 | Can Fite Biopharma Ltd | A3 adenosine receptor ligand for the treatment of ectopic fat accumulation |
WO2019227167A1 (en) * | 2018-06-01 | 2019-12-05 | The University Of Sydney | Compositions and treatments |
-
2020
- 2020-01-16 IL IL272078A patent/IL272078A/en unknown
-
2021
- 2021-01-14 BR BR112022013991A patent/BR112022013991A2/pt unknown
- 2021-01-14 MX MX2022008850A patent/MX2022008850A/es unknown
- 2021-01-14 EP EP21701863.9A patent/EP4090324A1/en active Pending
- 2021-01-14 WO PCT/IL2021/050046 patent/WO2021144799A1/en unknown
- 2021-01-14 CN CN202180009194.XA patent/CN114980873A/zh active Pending
- 2021-01-14 AU AU2021207766A patent/AU2021207766A1/en active Pending
- 2021-01-14 US US17/758,920 patent/US20230049415A1/en active Pending
- 2021-01-14 JP JP2022542922A patent/JP2023510003A/ja active Pending
- 2021-01-14 KR KR1020227027885A patent/KR20220137661A/ko unknown
- 2021-01-14 CA CA3164880A patent/CA3164880A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2023510003A (ja) | 2023-03-10 |
AU2021207766A1 (en) | 2022-07-21 |
KR20220137661A (ko) | 2022-10-12 |
IL272078A (en) | 2021-07-29 |
EP4090324A1 (en) | 2022-11-23 |
MX2022008850A (es) | 2022-08-10 |
WO2021144799A1 (en) | 2021-07-22 |
CN114980873A (zh) | 2022-08-30 |
CA3164880A1 (en) | 2021-07-22 |
US20230049415A1 (en) | 2023-02-16 |
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