BR112022012199A2 - Forma de dosagem com péletes de melatonina de liberação sustentada - Google Patents
Forma de dosagem com péletes de melatonina de liberação sustentadaInfo
- Publication number
- BR112022012199A2 BR112022012199A2 BR112022012199A BR112022012199A BR112022012199A2 BR 112022012199 A2 BR112022012199 A2 BR 112022012199A2 BR 112022012199 A BR112022012199 A BR 112022012199A BR 112022012199 A BR112022012199 A BR 112022012199A BR 112022012199 A2 BR112022012199 A2 BR 112022012199A2
- Authority
- BR
- Brazil
- Prior art keywords
- dosage form
- pellets
- melatonin
- sustained release
- release melatonin
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Zoology (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062962574P | 2020-01-17 | 2020-01-17 | |
| PCT/EP2021/050770 WO2021144403A1 (en) | 2020-01-17 | 2021-01-15 | Dosage form with sustained release melatonin pellets |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112022012199A2 true BR112022012199A2 (pt) | 2022-09-13 |
Family
ID=74285447
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112022012199A BR112022012199A2 (pt) | 2020-01-17 | 2021-01-15 | Forma de dosagem com péletes de melatonina de liberação sustentada |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11723862B2 (https=) |
| EP (1) | EP4090315A1 (https=) |
| JP (2) | JP2023510223A (https=) |
| CN (1) | CN114901256A (https=) |
| AU (1) | AU2021207284B2 (https=) |
| BR (1) | BR112022012199A2 (https=) |
| CA (1) | CA3163378A1 (https=) |
| WO (1) | WO2021144403A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024079125A1 (en) | 2022-10-14 | 2024-04-18 | Société des Produits Nestlé S.A. | Sustained release melatonin compositions |
| CN116172979B (zh) * | 2023-02-15 | 2024-10-15 | 浙江贝灵生物医药有限公司 | 一种褪黑素缓释小丸及其制备方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995003043A1 (en) * | 1993-07-26 | 1995-02-02 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University | Sustained release oral compositions containing melatonin |
| JP4641696B2 (ja) * | 1999-09-30 | 2011-03-02 | 大塚製薬株式会社 | 消化管下部溶解性コーティング製剤 |
| GB0025208D0 (en) * | 2000-10-13 | 2000-11-29 | Euro Celtique Sa | Delayed release pharmaceutical formulations |
| IL149377A (en) * | 2002-04-28 | 2012-10-31 | Neurim Pharma 1991 | Pharmaceutical formulation comprising melatonin for the potentiation of the effect of hypnotic compounds |
| KR100501827B1 (ko) | 2002-09-24 | 2005-07-20 | 한국화학연구원 | 다층 코팅법을 이용한 멜라토닌 함유 타게팅 약물 전달 기구 |
| US20070298117A1 (en) * | 2006-06-23 | 2007-12-27 | The Procter & Gamble Company | Compositions and kits comprising a melatonin component and a chondroprotective component |
| US20070299127A1 (en) * | 2006-06-23 | 2007-12-27 | The Procter & Gamble Company | Compositions and kits comprising a melatonin component and an omega-3-fatty acid component |
| US20080171085A1 (en) * | 2007-01-11 | 2008-07-17 | Natrol, Inc. | Novel biphasic delivery system for a pharmaceutical or nutraceutical composition and method of administration |
| WO2011160003A1 (en) * | 2010-06-17 | 2011-12-22 | Antioxidant Superfoods, Inc. | Improved health characteristic chewy or gummy candy confection |
| WO2012103411A2 (en) * | 2011-01-28 | 2012-08-02 | Zx Pharma, Llc | Controlled-release melatonin composition and related methods |
| US20120315337A1 (en) | 2011-06-07 | 2012-12-13 | Shah Syed | Multiparticulate 5-htp compositions and related methods |
| ITMI20112042A1 (it) * | 2011-11-10 | 2013-05-11 | Eratech S R L | Polvere da ricostituire prima dell'uso comprendente melatonina e preparazione iniettabile ottenibile da tale polvere. |
| CA3013472A1 (en) * | 2016-02-11 | 2017-08-17 | Biogen Ma Inc. | Pharmaceutical bead formulations comprising dimethyl fumarate |
| WO2017192843A1 (en) * | 2016-05-06 | 2017-11-09 | Physician's Seal, LLC | Valerian composition and related methods |
| GR1009541B (el) | 2018-02-26 | 2019-06-07 | Λαμδα Φαρμακευτικα Εργαστηρια Εφαρμοσμενης Ερευνας & Αναπτυξης Α.Ε. | Ποσιμα φαρμακευτικα διαλυματα που περιλαμβανουν μελατονινη |
| CN113490491A (zh) * | 2019-01-18 | 2021-10-08 | 雀巢产品有限公司 | 固体微粉化褪黑激素组合物 |
-
2021
- 2021-01-15 EP EP21701933.0A patent/EP4090315A1/en active Pending
- 2021-01-15 US US17/150,049 patent/US11723862B2/en active Active
- 2021-01-15 US US17/758,811 patent/US12558310B2/en active Active
- 2021-01-15 JP JP2022540995A patent/JP2023510223A/ja active Pending
- 2021-01-15 CN CN202180007944.XA patent/CN114901256A/zh active Pending
- 2021-01-15 AU AU2021207284A patent/AU2021207284B2/en active Active
- 2021-01-15 CA CA3163378A patent/CA3163378A1/en active Pending
- 2021-01-15 WO PCT/EP2021/050770 patent/WO2021144403A1/en not_active Ceased
- 2021-01-15 BR BR112022012199A patent/BR112022012199A2/pt unknown
-
2025
- 2025-08-12 JP JP2025134129A patent/JP2025169319A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20210220264A1 (en) | 2021-07-22 |
| US11723862B2 (en) | 2023-08-15 |
| AU2021207284A1 (en) | 2022-06-09 |
| EP4090315A1 (en) | 2022-11-23 |
| WO2021144403A1 (en) | 2021-07-22 |
| US20230045118A1 (en) | 2023-02-09 |
| US12558310B2 (en) | 2026-02-24 |
| JP2025169319A (ja) | 2025-11-12 |
| JP2023510223A (ja) | 2023-03-13 |
| CA3163378A1 (en) | 2021-07-22 |
| AU2021207284B2 (en) | 2026-02-12 |
| CN114901256A (zh) | 2022-08-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06W | Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette] |