BR112022009429A2 - Vacina de partícula lipídica de ácido nucleico encapsulando o mrna de hpv - Google Patents
Vacina de partícula lipídica de ácido nucleico encapsulando o mrna de hpvInfo
- Publication number
- BR112022009429A2 BR112022009429A2 BR112022009429A BR112022009429A BR112022009429A2 BR 112022009429 A2 BR112022009429 A2 BR 112022009429A2 BR 112022009429 A BR112022009429 A BR 112022009429A BR 112022009429 A BR112022009429 A BR 112022009429A BR 112022009429 A2 BR112022009429 A2 BR 112022009429A2
- Authority
- BR
- Brazil
- Prior art keywords
- nucleic acid
- encapsulating
- lipid particle
- acid lipid
- hpv mrna
- Prior art date
Links
- -1 NUCLEIC ACID LIPID Chemical class 0.000 title abstract 3
- 108020004707 nucleic acids Proteins 0.000 title abstract 3
- 102000039446 nucleic acids Human genes 0.000 title abstract 3
- 239000002245 particle Substances 0.000 title abstract 3
- 229960005486 vaccine Drugs 0.000 title abstract 3
- 125000004423 acyloxy group Chemical group 0.000 abstract 3
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 150000002632 lipids Chemical class 0.000 abstract 2
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 1
- 241000701806 Human papillomavirus Species 0.000 abstract 1
- 208000009608 Papillomavirus Infections Diseases 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 108020004999 messenger RNA Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
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- A61P31/20—Antivirals for DNA viruses
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- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
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- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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JP2019207001 | 2019-11-15 | ||
PCT/JP2020/042405 WO2021095838A1 (ja) | 2019-11-15 | 2020-11-13 | HPV mRNAを封入した核酸脂質粒子ワクチン |
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BR112022009429A2 true BR112022009429A2 (pt) | 2022-08-09 |
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BR112022009429A BR112022009429A2 (pt) | 2019-11-15 | 2020-11-13 | Vacina de partícula lipídica de ácido nucleico encapsulando o mrna de hpv |
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JPWO2022244815A1 (enrdf_load_stackoverflow) * | 2021-05-19 | 2022-11-24 | ||
EP4364752A1 (en) * | 2022-11-07 | 2024-05-08 | OncoDNA | Improved vaccine |
WO2024131833A1 (en) * | 2022-12-21 | 2024-06-27 | Abogen Biosciences (Shanghai) Co., Ltd. | Mrna-based hpv+ cancer vaccines, and uses thereof |
CN117398456A (zh) * | 2023-10-17 | 2024-01-16 | 中国药科大学 | 一种特异性标记异源蛋白的肿瘤新抗原疫苗体系及其应用 |
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JP6567824B2 (ja) * | 2011-10-12 | 2019-08-28 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | ヒトパピローマウイルスのワクチンおよびその使用方法 |
JP6517779B2 (ja) | 2013-03-12 | 2019-05-22 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | ヒトパピローマウイルスの改良型ワクチンおよびその使用方法 |
TW201534578A (zh) | 2013-07-08 | 2015-09-16 | Daiichi Sankyo Co Ltd | 新穎脂質 |
US10125092B2 (en) * | 2014-09-05 | 2018-11-13 | Novartis Ag | Lipids and lipid compositions for the delivery of active agents |
SG11201903674YA (en) * | 2016-10-26 | 2019-05-30 | Modernatx Inc | Messenger ribonucleic acids for enhancing immune responses and methods of use thereof |
MX2019009070A (es) * | 2017-02-01 | 2019-10-30 | Modernatx Inc | Composiciones de arnm terapeuticas inmunomoduladoras que codifican peptidos de mutacion de oncogenes de activacion. |
JP7060448B2 (ja) | 2018-05-29 | 2022-04-26 | 株式会社ミツバ | ギア、および減速機付きモータ |
JPWO2022244815A1 (enrdf_load_stackoverflow) * | 2021-05-19 | 2022-11-24 |
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2020
- 2020-11-13 JP JP2021556166A patent/JPWO2021095838A1/ja active Pending
- 2020-11-13 BR BR112022009429A patent/BR112022009429A2/pt unknown
- 2020-11-13 CA CA3160839A patent/CA3160839A1/en active Pending
- 2020-11-13 EP EP20887577.3A patent/EP4059515A4/en active Pending
- 2020-11-13 US US17/776,743 patent/US20220409540A1/en active Pending
- 2020-11-13 KR KR1020227016803A patent/KR20220102617A/ko not_active Withdrawn
- 2020-11-13 AU AU2020382378A patent/AU2020382378A1/en active Pending
- 2020-11-13 IL IL292989A patent/IL292989A/en unknown
- 2020-11-13 WO PCT/JP2020/042405 patent/WO2021095838A1/ja unknown
- 2020-11-13 CN CN202080077953.1A patent/CN114650841A/zh active Pending
- 2020-11-13 TW TW109139801A patent/TW202131945A/zh unknown
-
2025
- 2025-03-17 JP JP2025042566A patent/JP2025098089A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
WO2021095838A1 (ja) | 2021-05-20 |
JPWO2021095838A1 (enrdf_load_stackoverflow) | 2021-05-20 |
TW202131945A (zh) | 2021-09-01 |
KR20220102617A (ko) | 2022-07-20 |
CN114650841A (zh) | 2022-06-21 |
AU2020382378A1 (en) | 2022-06-30 |
EP4059515A4 (en) | 2024-02-14 |
CA3160839A1 (en) | 2022-05-09 |
JP2025098089A (ja) | 2025-07-01 |
US20220409540A1 (en) | 2022-12-29 |
EP4059515A1 (en) | 2022-09-21 |
IL292989A (en) | 2022-07-01 |
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