BR112021022763A2 - Gliceril tris(beta-hidroxibutirato) e ataques isquêmicos transitórios neuronais - Google Patents
Gliceril tris(beta-hidroxibutirato) e ataques isquêmicos transitórios neuronaisInfo
- Publication number
- BR112021022763A2 BR112021022763A2 BR112021022763A BR112021022763A BR112021022763A2 BR 112021022763 A2 BR112021022763 A2 BR 112021022763A2 BR 112021022763 A BR112021022763 A BR 112021022763A BR 112021022763 A BR112021022763 A BR 112021022763A BR 112021022763 A2 BR112021022763 A2 BR 112021022763A2
- Authority
- BR
- Brazil
- Prior art keywords
- hydroxybutyrate
- beta
- ischemic attacks
- glyceryl tris
- transient
- Prior art date
Links
- 230000001537 neural effect Effects 0.000 title abstract 4
- WHBMMWSBFZVSSR-UHFFFAOYSA-N 3-hydroxybutyric acid Chemical compound CC(O)CC(O)=O WHBMMWSBFZVSSR-UHFFFAOYSA-N 0.000 title abstract 3
- 239000007983 Tris buffer Substances 0.000 title abstract 3
- 125000003976 glyceryl group Chemical group [H]C([*])([H])C(O[H])([H])C(O[H])([H])[H] 0.000 title abstract 3
- 230000000302 ischemic effect Effects 0.000 title abstract 3
- 230000001052 transient effect Effects 0.000 title abstract 3
- 230000006735 deficit Effects 0.000 abstract 1
- 230000016273 neuron death Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
gliceril tris(beta-hidroxibutirato) e ataques isquêmicos transitórios neuronais. um método de uso de gliceril tris(beta-hidroxibutirato) na minimização, redução ou prevenção de déficit neuronal e/ou morte celular neuronal em relação a ataques isquêmicos transitórios neuronais (ntias) subsequentes em indivíduos que sofreram (ou em indivíduos que exibem sintomatologia de terem sofrido) pelo menos um ntia anterior.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2019/034592 WO2020242478A1 (en) | 2019-05-30 | 2019-05-30 | Glyceryl tris (beta-hydroxybutyrate) and neuronal transient ischemic attacks |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112021022763A2 true BR112021022763A2 (pt) | 2022-01-11 |
Family
ID=73552030
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112021022763A BR112021022763A2 (pt) | 2019-05-30 | 2019-05-30 | Gliceril tris(beta-hidroxibutirato) e ataques isquêmicos transitórios neuronais |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20220288006A1 (pt) |
| EP (1) | EP3976021A4 (pt) |
| JP (1) | JP7403861B2 (pt) |
| KR (1) | KR20220016145A (pt) |
| CN (1) | CN113710243A (pt) |
| BR (1) | BR112021022763A2 (pt) |
| CA (1) | CA3136552C (pt) |
| IL (1) | IL288343B2 (pt) |
| MX (1) | MX2021014546A (pt) |
| WO (1) | WO2020242478A1 (pt) |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU749638B2 (en) | 1997-03-17 | 2002-06-27 | Btg International Limited | Therapeutic compositions |
| GB0420856D0 (en) | 2004-09-20 | 2004-10-20 | Ketocytonyx Inc | Cns modulators |
| CN104224823A (zh) * | 2007-03-30 | 2014-12-24 | 有限会社爱泽世 | 生酮作用促进剂组合物 |
| MX2009011002A (es) * | 2007-04-12 | 2010-03-15 | Univ Minnesota | Composiciones de proteccion de isquemia/reperfusion y metodos de uso. |
| CN102105071A (zh) * | 2008-07-03 | 2011-06-22 | 艾克塞拉公司 | 用于治疗神经性障碍的乙酰乙酸的单甘油酯及其衍生物 |
| EP3322427A4 (en) * | 2015-07-10 | 2019-07-17 | Cognate Nutritionals, Inc. | MIGRAINE PROPHYLAXIS AND MITIGATION USING MEDIUM CHAIN TRIGLYCERIDES, KETONE ESTERS, AND OTHER KETOGENIC SOURCES |
| US20180177753A1 (en) * | 2016-12-23 | 2018-06-28 | Neuroenergy Ventures, Inc. | Glyceryl 3-hydroxybutyrates for migraine symptom management |
| US9925164B1 (en) | 2017-01-12 | 2018-03-27 | Neuroenergy Ventures, Inc. | Glyceryl 3-hydroxybutyrates for traumatic brain injury |
-
2019
- 2019-05-30 MX MX2021014546A patent/MX2021014546A/es unknown
- 2019-05-30 KR KR1020217042604A patent/KR20220016145A/ko unknown
- 2019-05-30 JP JP2021568387A patent/JP7403861B2/ja active Active
- 2019-05-30 WO PCT/US2019/034592 patent/WO2020242478A1/en unknown
- 2019-05-30 IL IL288343A patent/IL288343B2/en unknown
- 2019-05-30 CA CA3136552A patent/CA3136552C/en active Active
- 2019-05-30 EP EP19930919.6A patent/EP3976021A4/en active Pending
- 2019-05-30 BR BR112021022763A patent/BR112021022763A2/pt unknown
- 2019-05-30 CN CN201980095609.2A patent/CN113710243A/zh active Pending
- 2019-05-30 US US17/608,350 patent/US20220288006A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR20220016145A (ko) | 2022-02-08 |
| JP7403861B2 (ja) | 2023-12-25 |
| IL288343B2 (en) | 2024-04-01 |
| WO2020242478A1 (en) | 2020-12-03 |
| IL288343B1 (en) | 2023-12-01 |
| MX2021014546A (es) | 2022-01-06 |
| EP3976021A1 (en) | 2022-04-06 |
| US20220288006A1 (en) | 2022-09-15 |
| CA3136552A1 (en) | 2020-12-03 |
| JP2022537487A (ja) | 2022-08-26 |
| CA3136552C (en) | 2024-01-16 |
| IL288343A (en) | 2022-07-01 |
| EP3976021A4 (en) | 2022-11-09 |
| CN113710243A (zh) | 2021-11-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 4A ANUIDADE. |
|
| B08G | Application fees: restoration [chapter 8.7 patent gazette] | ||
| B06W | Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette] |