BR112021020037A2 - Polipeptídeos enpp1 e métodos para o uso dos mesmos - Google Patents
Polipeptídeos enpp1 e métodos para o uso dos mesmosInfo
- Publication number
- BR112021020037A2 BR112021020037A2 BR112021020037A BR112021020037A BR112021020037A2 BR 112021020037 A2 BR112021020037 A2 BR 112021020037A2 BR 112021020037 A BR112021020037 A BR 112021020037A BR 112021020037 A BR112021020037 A BR 112021020037A BR 112021020037 A2 BR112021020037 A2 BR 112021020037A2
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- enpp1
- polypeptides
- enpp1 polypeptides
- lives
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 238000001727 in vivo Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/04—Phosphoric diester hydrolases (3.1.4)
- C12Y301/04001—Phosphodiesterase I (3.1.4.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y306/00—Hydrolases acting on acid anhydrides (3.6)
- C12Y306/01—Hydrolases acting on acid anhydrides (3.6) in phosphorus-containing anhydrides (3.6.1)
- C12Y306/01009—Nucleotide diphosphatase (3.6.1.9), i.e. nucleotide-pyrophosphatase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Education & Sports Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962830230P | 2019-04-05 | 2019-04-05 | |
| US202062983142P | 2020-02-28 | 2020-02-28 | |
| US202062984650P | 2020-03-03 | 2020-03-03 | |
| PCT/US2020/026643 WO2020206302A1 (en) | 2019-04-05 | 2020-04-03 | Enpp1 polypeptides and methods of using same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112021020037A2 true BR112021020037A2 (pt) | 2021-12-07 |
Family
ID=72667412
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112021020037A BR112021020037A2 (pt) | 2019-04-05 | 2020-04-03 | Polipeptídeos enpp1 e métodos para o uso dos mesmos |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20220195402A1 (https=) |
| EP (1) | EP3947660A4 (https=) |
| JP (2) | JP2022527557A (https=) |
| KR (1) | KR20210149146A (https=) |
| CN (1) | CN113993993A (https=) |
| AU (2) | AU2020256253B2 (https=) |
| BR (1) | BR112021020037A2 (https=) |
| CA (1) | CA3136118A1 (https=) |
| IL (1) | IL286946A (https=) |
| MX (1) | MX2021012197A (https=) |
| TW (1) | TW202043292A (https=) |
| WO (1) | WO2020206302A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021252549A1 (en) | 2020-06-09 | 2021-12-16 | Inozyme Pharma, Inc. | Soluble enpp1 or enpp3 proteins and uses thereof |
| CA3246877A1 (en) * | 2022-03-30 | 2023-10-05 | Yale University | METHOD AND COMPOSITIONS FOR THE TREATMENT, ALLEVIATION AND/OR PREVENTION OF DIFFUSE IDIOPATHIC SKELETAL HYPEROSTOSIS (DISH) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995019570A1 (en) * | 1994-01-14 | 1995-07-20 | Genentech, Inc. | Antagonists to insulin receptor tyrosine kinase inhibitor |
| ES2708565T3 (es) * | 2013-03-15 | 2019-04-10 | Atyr Pharma Inc | Conjugados de Fc-histidil-ARNt sintetasa |
| EP4414028A3 (en) * | 2015-05-19 | 2024-11-27 | Yale University | Compositions for treating pathological calcification conditions, and methods using same |
-
2020
- 2020-04-03 CA CA3136118A patent/CA3136118A1/en active Pending
- 2020-04-03 BR BR112021020037A patent/BR112021020037A2/pt unknown
- 2020-04-03 JP JP2021559256A patent/JP2022527557A/ja active Pending
- 2020-04-03 MX MX2021012197A patent/MX2021012197A/es unknown
- 2020-04-03 EP EP20783595.0A patent/EP3947660A4/en active Pending
- 2020-04-03 CN CN202080041580.2A patent/CN113993993A/zh active Pending
- 2020-04-03 AU AU2020256253A patent/AU2020256253B2/en active Active
- 2020-04-03 KR KR1020217036178A patent/KR20210149146A/ko active Pending
- 2020-04-03 US US17/601,387 patent/US20220195402A1/en not_active Abandoned
- 2020-04-03 WO PCT/US2020/026643 patent/WO2020206302A1/en not_active Ceased
- 2020-04-06 TW TW109111502A patent/TW202043292A/zh unknown
-
2021
- 2021-10-04 IL IL286946A patent/IL286946A/en unknown
-
2024
- 2024-08-26 US US18/815,173 patent/US20250230423A1/en active Pending
- 2024-09-26 JP JP2024167228A patent/JP2024178422A/ja active Pending
-
2026
- 2026-01-30 AU AU2026200700A patent/AU2026200700A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| TW202043292A (zh) | 2020-12-01 |
| AU2020256253A1 (en) | 2021-10-28 |
| AU2020256253B2 (en) | 2026-02-19 |
| US20250230423A1 (en) | 2025-07-17 |
| KR20210149146A (ko) | 2021-12-08 |
| US20220195402A1 (en) | 2022-06-23 |
| CA3136118A1 (en) | 2020-10-08 |
| EP3947660A4 (en) | 2023-01-25 |
| JP2024178422A (ja) | 2024-12-24 |
| WO2020206302A1 (en) | 2020-10-08 |
| EP3947660A1 (en) | 2022-02-09 |
| JP2022527557A (ja) | 2022-06-02 |
| MX2021012197A (es) | 2022-01-06 |
| CN113993993A (zh) | 2022-01-28 |
| AU2026200700A1 (en) | 2026-02-19 |
| IL286946A (en) | 2021-12-01 |
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