BR112021019476A2 - Compostos para uso no tratamento ou profilaxia de dor, inflamação e / ou autoimunidade - Google Patents
Compostos para uso no tratamento ou profilaxia de dor, inflamação e / ou autoimunidadeInfo
- Publication number
- BR112021019476A2 BR112021019476A2 BR112021019476A BR112021019476A BR112021019476A2 BR 112021019476 A2 BR112021019476 A2 BR 112021019476A2 BR 112021019476 A BR112021019476 A BR 112021019476A BR 112021019476 A BR112021019476 A BR 112021019476A BR 112021019476 A2 BR112021019476 A2 BR 112021019476A2
- Authority
- BR
- Brazil
- Prior art keywords
- autoimmunity
- inflammation
- pain
- prophylaxis
- treatment
- Prior art date
Links
- 206010061218 Inflammation Diseases 0.000 title abstract 5
- 230000005784 autoimmunity Effects 0.000 title abstract 5
- 230000004054 inflammatory process Effects 0.000 title abstract 5
- 238000011321 prophylaxis Methods 0.000 title abstract 4
- 238000011282 treatment Methods 0.000 title abstract 4
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000002981 neuropathic effect Effects 0.000 abstract 1
- 230000003040 nociceptive effect Effects 0.000 abstract 1
- 229960003742 phenol Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/22—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19153315 | 2019-01-23 | ||
| PCT/EP2020/051528 WO2020152226A1 (en) | 2019-01-23 | 2020-01-22 | Compounds for use in the treatment or prophylaxis of pain, inflammation and/or autoimmunity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112021019476A2 true BR112021019476A2 (pt) | 2021-11-30 |
Family
ID=65228356
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112021019476A BR112021019476A2 (pt) | 2019-01-23 | 2020-01-22 | Compostos para uso no tratamento ou profilaxia de dor, inflamação e / ou autoimunidade |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US11891350B2 (https=) |
| EP (1) | EP3860582B1 (https=) |
| JP (2) | JP7611148B2 (https=) |
| KR (1) | KR20210119403A (https=) |
| CN (1) | CN113329746B (https=) |
| AU (1) | AU2020210831B2 (https=) |
| BR (1) | BR112021019476A2 (https=) |
| CA (1) | CA3118996A1 (https=) |
| DK (1) | DK3860582T3 (https=) |
| ES (1) | ES2913977T3 (https=) |
| IL (1) | IL282718B2 (https=) |
| PL (1) | PL3860582T3 (https=) |
| PT (1) | PT3860582T (https=) |
| RS (1) | RS63270B1 (https=) |
| SG (1) | SG11202111773QA (https=) |
| WO (1) | WO2020152226A1 (https=) |
| ZA (1) | ZA202107346B (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3939578A1 (en) * | 2020-07-13 | 2022-01-19 | Novaremed Ltd. | Compounds for treatment or prevention of an infection resulting from a coronavirus and/or a coronavirus-induced disease |
| WO2026037478A1 (en) | 2023-08-11 | 2026-02-19 | Novaremed AG | (s,s)-(3-o-(propan-2-ol)-2-amino-prop-1-yl-4-hydroxybenzene and its analogues for the treatment of chronic pain |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7642290B2 (en) | 2002-10-03 | 2010-01-05 | Novaremed Limited | Compounds for use in the treatment of autoimmune diseases, immuno-allergical diseases and organ or tissue transplantation rejection |
| JP4939396B2 (ja) * | 2004-03-26 | 2012-05-23 | ノヴァレメッド リミテッド | Ａｉｄｓ及び他のウイルス性疾患及びｈｉｖ関連感染症の改善又はその治療用化合物及びそのような化合物を含む組成物、そのような疾患及び感染症の治療方法及びそのような化合物及び組成物の製造方法 |
| GB0804213D0 (en) | 2008-03-06 | 2008-04-16 | New Era Biotech Ltd | A method of printing or preventing pain |
| CN102821761B (zh) * | 2009-09-09 | 2015-06-10 | 诺瓦麦有限公司 | 用于治疗疼痛和炎症的n-取代的苯丙酰胺或苯丙烯酰胺 |
| US8802734B2 (en) | 2009-09-09 | 2014-08-12 | Novaremed Limited | Method of treating or preventing pain |
| GB0916073D0 (en) | 2009-09-14 | 2009-10-28 | Cintec Int Ltd | Improvements in and relating to building anchor systems |
| AU2012348529B2 (en) | 2011-12-08 | 2017-03-30 | Novaremed Ltd. | Isolated stereoisomeric forms of (S) 2-N (3-O-(propan 2-ol) -1-propyl-4-hydroxybenzene) -3-phenylpropylamide |
-
2020
- 2020-01-22 US US17/295,788 patent/US11891350B2/en active Active
- 2020-01-22 EP EP20703152.7A patent/EP3860582B1/en active Active
- 2020-01-22 PT PT207031527T patent/PT3860582T/pt unknown
- 2020-01-22 BR BR112021019476A patent/BR112021019476A2/pt unknown
- 2020-01-22 KR KR1020217023524A patent/KR20210119403A/ko not_active Ceased
- 2020-01-22 AU AU2020210831A patent/AU2020210831B2/en active Active
- 2020-01-22 ES ES20703152T patent/ES2913977T3/es active Active
- 2020-01-22 WO PCT/EP2020/051528 patent/WO2020152226A1/en not_active Ceased
- 2020-01-22 CN CN202080010393.8A patent/CN113329746B/zh active Active
- 2020-01-22 JP JP2021543276A patent/JP7611148B2/ja active Active
- 2020-01-22 DK DK20703152.7T patent/DK3860582T3/da active
- 2020-01-22 IL IL282718A patent/IL282718B2/en unknown
- 2020-01-22 SG SG11202111773QA patent/SG11202111773QA/en unknown
- 2020-01-22 CA CA3118996A patent/CA3118996A1/en active Pending
- 2020-01-22 RS RS20220510A patent/RS63270B1/sr unknown
- 2020-01-22 PL PL20703152.7T patent/PL3860582T3/pl unknown
-
2021
- 2021-09-23 ZA ZA2021/07346A patent/ZA202107346B/en unknown
-
2024
- 2024-12-23 JP JP2024226332A patent/JP2025036479A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2020210831B2 (en) | 2025-02-13 |
| ZA202107346B (en) | 2023-10-25 |
| JP7611148B2 (ja) | 2025-01-09 |
| PL3860582T3 (pl) | 2022-08-01 |
| ES2913977T3 (es) | 2022-06-07 |
| DK3860582T3 (da) | 2022-05-23 |
| IL282718B1 (en) | 2024-04-01 |
| KR20210119403A (ko) | 2021-10-05 |
| EP3860582A1 (en) | 2021-08-11 |
| US11891350B2 (en) | 2024-02-06 |
| IL282718B2 (en) | 2024-08-01 |
| CA3118996A1 (en) | 2020-07-30 |
| SG11202111773QA (en) | 2021-11-29 |
| AU2020210831A1 (en) | 2021-05-20 |
| JP2025036479A (ja) | 2025-03-14 |
| CN113329746A (zh) | 2021-08-31 |
| RS63270B1 (sr) | 2022-06-30 |
| JP2022518288A (ja) | 2022-03-14 |
| IL282718A (en) | 2021-06-30 |
| WO2020152226A1 (en) | 2020-07-30 |
| PT3860582T (pt) | 2022-07-08 |
| CN113329746B (zh) | 2025-05-02 |
| EP3860582B1 (en) | 2022-05-04 |
| US20220002228A1 (en) | 2022-01-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06W | Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette] | ||
| B25G | Requested change of headquarter approved |
Owner name: NOVAREMED LTD. (CH) |