BR112021015170A2 - Alvos gênicos combinados para imunoterapia aprimorada - Google Patents

Alvos gênicos combinados para imunoterapia aprimorada Download PDF

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Publication number
BR112021015170A2
BR112021015170A2 BR112021015170-2A BR112021015170A BR112021015170A2 BR 112021015170 A2 BR112021015170 A2 BR 112021015170A2 BR 112021015170 A BR112021015170 A BR 112021015170A BR 112021015170 A2 BR112021015170 A2 BR 112021015170A2
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Brazil
Prior art keywords
seq
nos
zc3h12a
targeted
socs1
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BR112021015170-2A
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English (en)
Portuguese (pt)
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Micah Benson
Michael Schlabach
Gregory Kryukov
Anne Louise CADZOW
Isabelle Fleur Le Mercier
Frank STEGMEIER
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KSQ Therapeutics, Inc.
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Publication of BR112021015170A2 publication Critical patent/BR112021015170A2/pt

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    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • A61K40/00Cellular immunotherapy
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    • C12N9/14Hydrolases (3)
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    • C12N9/22Ribonucleases [RNase]; Deoxyribonucleases [DNase]
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BR112021015170-2A 2019-02-04 2020-02-04 Alvos gênicos combinados para imunoterapia aprimorada BR112021015170A2 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962800999P 2019-02-04 2019-02-04
US62/800,999 2019-02-04
US201962818677P 2019-03-14 2019-03-14
US62/818,677 2019-03-14
PCT/US2020/016623 WO2020163365A2 (en) 2019-02-04 2020-02-04 Combination gene targets for improved immunotherapy

Publications (1)

Publication Number Publication Date
BR112021015170A2 true BR112021015170A2 (pt) 2021-09-28

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BR112021015170-2A BR112021015170A2 (pt) 2019-02-04 2020-02-04 Alvos gênicos combinados para imunoterapia aprimorada

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US (1) US20200347386A1 (https=)
EP (1) EP3920942A4 (https=)
JP (2) JP2022519595A (https=)
KR (1) KR20210138587A (https=)
CN (1) CN113396216A (https=)
AU (1) AU2020217715A1 (https=)
BR (1) BR112021015170A2 (https=)
CA (1) CA3128823A1 (https=)
IL (1) IL285307A (https=)
MX (1) MX2021009357A (https=)
SG (1) SG11202108452WA (https=)
WO (1) WO2020163365A2 (https=)

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GB202013477D0 (en) * 2020-08-27 2020-10-14 Quell Therapeutics Ltd Nucleic acid constructs for expressing polypeptides in cells
TW202227625A (zh) * 2020-08-28 2022-07-16 美商建南德克公司 宿主細胞蛋白質之CRISPR/Cas9多重剔除
WO2022133329A1 (en) * 2020-12-17 2022-06-23 University Of Florida Research Foundation, Incorporated Method for programmable control of rna transcript levels with autoregulated crispr-cas13d
EP4288541A1 (en) 2021-02-05 2023-12-13 Christiana Care Gene Editing Institute, Inc. Methods of and compositions for reducing gene expression and/or activity
EP4305153A1 (en) 2021-03-09 2024-01-17 CRISPR Therapeutics AG Genetically engineered t cells with ptpn2 knockout have improved functionality and anti-tumor activity
WO2023015213A1 (en) * 2021-08-03 2023-02-09 Spotlight Therapeutics Ptpn2 specific guide rnas and uses thereof
AU2022366987A1 (en) 2021-10-14 2024-05-16 Arsenal Biosciences, Inc. Immune cells having co-expressed shrnas and logic gate systems
WO2023082640A1 (zh) * 2021-11-10 2023-05-19 清华大学 增强免疫细胞持久性的方法
MX2024006243A (es) * 2021-11-23 2024-06-11 Kumquat Biosciences Inc Compuestos que contienen heteroatomos y usos de estos.
JP2025501358A (ja) * 2022-01-05 2025-01-17 蘇州系統医学研究所 T細胞受容体、その製造方法、及び使用
EP4471128A4 (en) * 2022-01-29 2026-03-04 Suzhou Grit Biotechnology Co Ltd Modified tumor infiltrating lymphocyte and use thereof
KR20250158048A (ko) 2023-03-03 2025-11-05 아스널 바이오사이언시스, 인크. Psma 및 ca9을 표적으로 하는 시스템
CN120981456A (zh) 2023-05-24 2025-11-18 金橘生物科技公司 杂环化合物及其用途
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