BR112020008001A2 - anticorpo anti-glico-muc1 ou fragmento de ligação de antígeno, proteína de fusão, receptor de antígeno quimérico, conjugado de anticorpo-fármaco, ácido nucleico, vetor, célula hospedeira, composição farmacêutica, e, métodos de tratar câncer e de detectar câncer em uma amostra biológica. - Google Patents
anticorpo anti-glico-muc1 ou fragmento de ligação de antígeno, proteína de fusão, receptor de antígeno quimérico, conjugado de anticorpo-fármaco, ácido nucleico, vetor, célula hospedeira, composição farmacêutica, e, métodos de tratar câncer e de detectar câncer em uma amostra biológica. Download PDFInfo
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- BR112020008001A2 BR112020008001A2 BR112020008001-2A BR112020008001A BR112020008001A2 BR 112020008001 A2 BR112020008001 A2 BR 112020008001A2 BR 112020008001 A BR112020008001 A BR 112020008001A BR 112020008001 A2 BR112020008001 A2 BR 112020008001A2
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- antibody
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3076—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties
- C07K16/3092—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties against tumour-associated mucins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4725—Mucins, e.g. human intestinal mucin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
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- Molecular Biology (AREA)
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- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
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- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2017/058036 WO2019083506A1 (en) | 2017-10-24 | 2017-10-24 | ANTI-GLYCO-MUC1 ANTIBODIES AND USES THEREOF |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112020008001A2 true BR112020008001A2 (pt) | 2020-10-20 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| BR112020008001-2A BR112020008001A2 (pt) | 2017-10-24 | 2017-10-24 | anticorpo anti-glico-muc1 ou fragmento de ligação de antígeno, proteína de fusão, receptor de antígeno quimérico, conjugado de anticorpo-fármaco, ácido nucleico, vetor, célula hospedeira, composição farmacêutica, e, métodos de tratar câncer e de detectar câncer em uma amostra biológica. |
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| EP (1) | EP3700936A4 (enExample) |
| JP (2) | JP7358367B2 (enExample) |
| KR (2) | KR102608763B1 (enExample) |
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| AU (1) | AU2017436815B2 (enExample) |
| BR (1) | BR112020008001A2 (enExample) |
| CA (1) | CA3078812A1 (enExample) |
| IL (1) | IL274202A (enExample) |
| MX (1) | MX2020004220A (enExample) |
| WO (1) | WO2019083506A1 (enExample) |
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| MX2020004220A (es) * | 2017-10-24 | 2020-10-05 | Go Therapeutics Inc | Anticuerpos anti-glico-muc1 y sus usos. |
| WO2022026809A1 (en) * | 2020-07-31 | 2022-02-03 | R.P. Scherer Technologies, Llc | Antibody specific for mucin-1 and methods of use thereof |
| CA3230370A1 (en) * | 2021-08-27 | 2023-03-02 | Peptron, Inc. | Novel anti-muc1 antibody and use thereof |
| MX2024007653A (es) * | 2021-12-21 | 2024-07-04 | Merus Nv | Dominios de union contra mucina1 (muc1) asociada al cancer. |
| CN114796498A (zh) * | 2022-01-27 | 2022-07-29 | 中国农业大学 | 抑制muc1糖基化修饰的物质在提高乳腺癌细胞对抗乳腺癌药物的敏感度中的应用 |
| WO2024213106A1 (zh) * | 2023-04-13 | 2024-10-17 | 江苏恒瑞医药股份有限公司 | 特异性结合egfr和muc1的抗原结合分子、其药物偶联物及其医药用途 |
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| AU2001249760B2 (en) * | 2000-03-30 | 2005-04-21 | Dyax Corp. | Mucin-1 specific binding members and methods of use thereof |
| DE10303664A1 (de) * | 2003-01-23 | 2004-08-12 | Nemod Immuntherapie Ag | Erkennungsmoleküle zur Behandlung und Detektion von Tumoren |
| AU2007304590A1 (en) * | 2006-10-04 | 2008-04-10 | Cancer Research Technology Limited | Generation of a cancer-specific immune response toward MUC1 and cancer specific MUC1 antibodies |
| EP2014302A1 (en) * | 2007-07-12 | 2009-01-14 | Institut Curie | An antibody specific for the Tn antigen for the treatment of cancer |
| CN101978054B (zh) * | 2007-12-05 | 2013-05-29 | 协和发酵麒麟株式会社 | 能够与肝素结合性表皮生长因子样生长因子结合的单克隆抗体 |
| CN102264765B (zh) * | 2008-10-28 | 2016-01-20 | 盐野义制药株式会社 | 抗muc1抗体 |
| EP2281844A1 (en) * | 2009-07-31 | 2011-02-09 | Glycotope GmbH | MUC 1 antibodies |
| US10208125B2 (en) * | 2013-07-15 | 2019-02-19 | University of Pittsburgh—of the Commonwealth System of Higher Education | Anti-mucin 1 binding agents and uses thereof |
| EP3102236A4 (en) * | 2014-02-05 | 2017-08-30 | The University of Chicago | Chimeric antigen receptors recognizing cancer-specific tn glycopeptide variants |
| AU2015254257B2 (en) * | 2014-04-28 | 2021-02-25 | Medicinal Chemistry Pharmaceuticals, Co., Ltd. | Anti-MUC1 antibody or antigen-binding fragment of same, and use thereof |
| MX2020004220A (es) * | 2017-10-24 | 2020-10-05 | Go Therapeutics Inc | Anticuerpos anti-glico-muc1 y sus usos. |
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Also Published As
| Publication number | Publication date |
|---|---|
| IL274202A (en) | 2020-06-30 |
| AU2017436815B2 (en) | 2025-05-29 |
| WO2019083506A1 (en) | 2019-05-02 |
| EP3700936A4 (en) | 2021-05-26 |
| CN111479828B (zh) | 2024-07-05 |
| AU2017436815A1 (en) | 2020-04-23 |
| KR102608763B1 (ko) | 2023-11-30 |
| CN111479828A (zh) | 2020-07-31 |
| EP3700936A1 (en) | 2020-09-02 |
| JP2021510307A (ja) | 2021-04-22 |
| MX2020004220A (es) | 2020-10-05 |
| JP2024001073A (ja) | 2024-01-09 |
| JP7358367B2 (ja) | 2023-10-10 |
| CA3078812A1 (en) | 2019-05-02 |
| KR20230165874A (ko) | 2023-12-05 |
| KR102832078B1 (ko) | 2025-07-08 |
| KR20200067885A (ko) | 2020-06-12 |
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