BR112020000681A2 - detecção e classificação de cancro utilizando análise de metilome - Google Patents

detecção e classificação de cancro utilizando análise de metilome Download PDF

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Publication number
BR112020000681A2
BR112020000681A2 BR112020000681-5A BR112020000681A BR112020000681A2 BR 112020000681 A2 BR112020000681 A2 BR 112020000681A2 BR 112020000681 A BR112020000681 A BR 112020000681A BR 112020000681 A2 BR112020000681 A2 BR 112020000681A2
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Prior art keywords
dna
cell
cancer
free
methylated
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BR112020000681-5A
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English (en)
Portuguese (pt)
Inventor
Daniel Diniz De Carvalho
Scott Victor Bratman
Rajat SINGHANIA
Ankur Ravinarayana CHAKRAVARTHY
Shu Yi SHEN
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University Health Network
Sinai Health System
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Publication of BR112020000681A2 publication Critical patent/BR112020000681A2/pt

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    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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    • C12Q1/6869—Methods for sequencing
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    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • G—PHYSICS
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    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
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    • C12Q2522/00—Reaction characterised by the use of non-enzymatic proteins
    • C12Q2522/10—Nucleic acid binding proteins
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    • C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
    • C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
    • C12Q2537/164—Methylation detection other then bisulfite or methylation sensitive restriction endonucleases
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers
    • G—PHYSICS
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    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
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BR112020000681-5A 2017-07-12 2018-07-11 detecção e classificação de cancro utilizando análise de metilome BR112020000681A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762531527P 2017-07-12 2017-07-12
US62/531,527 2017-07-12
PCT/CA2018/000141 WO2019010564A1 (en) 2017-07-12 2018-07-11 DETECTION AND CLASSIFICATION OF CANCER USING METHYLOME ANALYSIS

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BR112020000681A2 true BR112020000681A2 (pt) 2020-07-14

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US (2) US12031184B2 (https=)
EP (1) EP3652741A4 (https=)
JP (2) JP2020537487A (https=)
KR (2) KR102628878B1 (https=)
CN (2) CN118600004A (https=)
BR (1) BR112020000681A2 (https=)
CA (1) CA3069754A1 (https=)
WO (1) WO2019010564A1 (https=)

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KR102491322B1 (ko) * 2022-03-29 2023-01-27 주식회사 아이엠비디엑스 암 진단을 위한 다중 분석 예측 모델의 제조 방법
CN119604623A (zh) * 2022-05-25 2025-03-11 阿黛拉公司 用于无细胞核酸处理的方法和系统
CN115274124B (zh) * 2022-07-22 2023-11-14 江苏先声医学诊断有限公司 一种基于数据驱动的肿瘤早筛靶向Panel和分类模型的动态优化方法
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Publication number Publication date
EP3652741A1 (en) 2020-05-20
KR102628878B1 (ko) 2024-01-23
US20200308651A1 (en) 2020-10-01
US20220251665A1 (en) 2022-08-11
CN118600004A (zh) 2024-09-06
JP2020537487A (ja) 2020-12-24
EP3652741A4 (en) 2021-04-21
CA3069754A1 (en) 2019-01-17
WO2019010564A1 (en) 2019-01-17
JP2023139162A (ja) 2023-10-03
KR102930572B1 (ko) 2026-02-24
US12031184B2 (en) 2024-07-09
KR20240018667A (ko) 2024-02-13
KR20200032127A (ko) 2020-03-25
CN111094590A (zh) 2020-05-01

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