BR112019014388A8 - Composição de enchimento, e, métodos para preparação da composição de enchimento e para aumento de tecido mole - Google Patents
Composição de enchimento, e, métodos para preparação da composição de enchimento e para aumento de tecido moleInfo
- Publication number
- BR112019014388A8 BR112019014388A8 BR112019014388A BR112019014388A BR112019014388A8 BR 112019014388 A8 BR112019014388 A8 BR 112019014388A8 BR 112019014388 A BR112019014388 A BR 112019014388A BR 112019014388 A BR112019014388 A BR 112019014388A BR 112019014388 A8 BR112019014388 A8 BR 112019014388A8
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- compositions
- filling composition
- preparing
- soft tissue
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/0059—Cosmetic or alloplastic implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/12—Mammary prostheses and implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/26—Mixtures of macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/58—Materials at least partially resorbable by the body
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
- C08L1/08—Cellulose derivatives
- C08L1/26—Cellulose ethers
- C08L1/28—Alkyl ethers
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
- C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L83/00—Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon only; Compositions of derivatives of such polymers
- C08L83/04—Polysiloxanes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/06—Flowable or injectable implant compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/04—Materials or treatment for tissue regeneration for mammary reconstruction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/34—Materials or treatment for tissue regeneration for soft tissue reconstruction
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Animal Behavior & Ethology (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Prostheses (AREA)
Abstract
A presente invenção refere-se às composições na forma de dispersão de óleo-em-água compreendendo um óleo de silicone tendo um diâmetro de gotícula médio de cerca de 2.000 micrometros ou menos e um agente espessante polimérico. Estas composições são úteis para estimulação da produção de colágeno em pacientes humanos e outros mamíferos, e têm aplicações para aumento de tecido mole em vários procedimentos médicos e cosméticos. A presente invenção refere-se, também, aos métodos para preparação destas composições e aos métodos para estimulação da produção de colágeno em pacientes humanos ou outros mamíferos que necessitam da mesma. Em contraste com a técnica anterior, as composições e os métodos da presente invenção são particularmente adequados para estimulação da produção de colágeno de alta qualidade que é uniforme, liso, de longa duração, e tem boa integridade estrutural.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15/405,240 | 2017-01-12 | ||
| US15/405,240 US9993578B1 (en) | 2017-01-12 | 2017-01-12 | Silicone oil-in-water composition useful as an injectable filler and as a scaffold for collagen growth |
| PCT/US2018/013512 WO2018132669A1 (en) | 2017-01-12 | 2018-01-12 | Silicone oil-in-water composition useful as an injectable filler and as a scaffold for collagen growth |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BR112019014388A2 BR112019014388A2 (pt) | 2020-02-11 |
| BR112019014388A8 true BR112019014388A8 (pt) | 2022-08-02 |
| BR112019014388B1 BR112019014388B1 (pt) | 2023-01-24 |
Family
ID=62485630
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112019014388-2A BR112019014388B1 (pt) | 2017-01-12 | 2018-01-12 | Composição de enchimento, método para preparação da composição de enchimento e uso da composição |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US9993578B1 (pt) |
| EP (1) | EP3568118B1 (pt) |
| JP (1) | JP7074951B2 (pt) |
| KR (1) | KR102527685B1 (pt) |
| CN (1) | CN110300569B (pt) |
| AU (1) | AU2018207566A1 (pt) |
| BR (1) | BR112019014388B1 (pt) |
| CA (1) | CA3049877C (pt) |
| CL (1) | CL2019001951A1 (pt) |
| CO (1) | CO2019008710A2 (pt) |
| ES (1) | ES2928429T3 (pt) |
| HU (1) | HUE060068T2 (pt) |
| MA (1) | MA47269A (pt) |
| MX (1) | MX2019008399A (pt) |
| PL (1) | PL3568118T3 (pt) |
| SG (1) | SG11201906344WA (pt) |
| WO (1) | WO2018132669A1 (pt) |
| ZA (1) | ZA201905308B (pt) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7319793B2 (ja) * | 2019-03-05 | 2023-08-02 | 第一工業製薬株式会社 | 皮下または粘膜下用膨張剤 |
| US10517730B1 (en) | 2019-05-20 | 2019-12-31 | Loria Products Llc | Penile sleeve devices and penile stocking insert and methods of making the same |
| WO2021056053A1 (en) * | 2019-09-25 | 2021-04-01 | Formulae 8 Pty Ltd | Silicone droplets |
| US20230321319A1 (en) * | 2020-08-18 | 2023-10-12 | Innate S.R.L. | Injectable composition and use of said composition |
| KR102358306B1 (ko) | 2020-10-08 | 2022-02-07 | 김예주 | 목주름 개선을 위한 주사용 조성물 |
| CA3199873A1 (en) * | 2021-01-12 | 2022-07-21 | Victor Loria | Multiple viscosity oil-in-water composition useful as an injectable filler and a scaffold for collagen growth |
| CN113144288A (zh) * | 2021-04-26 | 2021-07-23 | 磐升瑞祥(山东)生物工程有限公司 | 一种复合多组分的胶原蛋白微乳填充剂及其制备方法 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6022018B2 (ja) | 1981-11-27 | 1985-05-30 | 信越化学工業株式会社 | シリコ−ン水性エマルジヨン組成物 |
| US4960764A (en) | 1987-03-06 | 1990-10-02 | Richardson-Vicks Inc. | Oil-in-water-in-silicone emulsion compositions |
| JPH01148264A (ja) * | 1987-12-04 | 1989-06-09 | Atsushi Zaisho | 美容形成用注射物質 |
| US5300286A (en) | 1992-07-14 | 1994-04-05 | Dow Corning Corporation | Silicone emulsion for personal care application |
| US5523291A (en) * | 1993-09-07 | 1996-06-04 | Datascope Investment Corp. | Injectable compositions for soft tissue augmentation |
| US5861149A (en) * | 1997-06-04 | 1999-01-19 | Polyheal Ltd. | Methods for wound treatment |
| US20020025340A1 (en) * | 2000-08-30 | 2002-02-28 | Dyer Wallace K. | Methods and compositions for tissue augmentation |
| TW552295B (en) * | 2002-11-13 | 2003-09-11 | Maxigen Biothch Inc | Injectable collagen implant and methods of preparation thereof |
| WO2009055610A1 (en) * | 2007-10-26 | 2009-04-30 | Cytori Therapeutics, Inc. | Syringe system for controlled delivery or removal of material |
| AU2008345068A1 (en) * | 2007-12-26 | 2009-07-09 | Mark A. Pinsky | Collagen formulations for improved skin care |
| CN102575229A (zh) * | 2009-08-11 | 2012-07-11 | 约翰霍普金斯大学 | 用于植入经加工的脂肪组织和经加工的脂肪组织产品的组合物和方法 |
| US20140079686A1 (en) * | 2010-12-06 | 2014-03-20 | Shikha P. Barman | Methods For Treating Baldness And Promoting Hair Growth |
| CN102178617B (zh) * | 2011-05-09 | 2012-10-10 | 刘佩华 | 具有皮肤修复和养护功能的蛋白质护肤品 |
| CN102204881A (zh) * | 2011-06-08 | 2011-10-05 | 复旦大学 | 含喜树碱或其衍生物的凝胶缓释注射剂及其制备方法 |
| CN102284082B (zh) * | 2011-07-01 | 2014-03-26 | 董萍 | 一种可用于面部美容的皮下软组织填充定位纤维蛋白复合物及其制备方法 |
| EP2835130A1 (en) * | 2013-08-05 | 2015-02-11 | Polichem SA | Composition for skin anti-ageing treatment |
| CN103834053B (zh) * | 2014-02-28 | 2016-04-27 | 陕西佰傲再生医学有限公司 | 一种可注射的交联透明质酸凝胶及其制备方法 |
| US20160354516A1 (en) | 2015-06-05 | 2016-12-08 | Gary Chuang | Minimally Invasive Method of Augmenting a Glans Penis with Intradermal Filler Material |
-
2017
- 2017-01-12 US US15/405,240 patent/US9993578B1/en active Active
-
2018
- 2018-01-12 HU HUE18738921A patent/HUE060068T2/hu unknown
- 2018-01-12 BR BR112019014388-2A patent/BR112019014388B1/pt active IP Right Grant
- 2018-01-12 MX MX2019008399A patent/MX2019008399A/es unknown
- 2018-01-12 CN CN201880012240.XA patent/CN110300569B/zh active Active
- 2018-01-12 EP EP18738921.8A patent/EP3568118B1/en active Active
- 2018-01-12 MA MA047269A patent/MA47269A/fr unknown
- 2018-01-12 PL PL18738921.8T patent/PL3568118T3/pl unknown
- 2018-01-12 KR KR1020197023684A patent/KR102527685B1/ko active IP Right Grant
- 2018-01-12 ES ES18738921T patent/ES2928429T3/es active Active
- 2018-01-12 CA CA3049877A patent/CA3049877C/en active Active
- 2018-01-12 AU AU2018207566A patent/AU2018207566A1/en not_active Abandoned
- 2018-01-12 JP JP2019538423A patent/JP7074951B2/ja active Active
- 2018-01-12 SG SG11201906344WA patent/SG11201906344WA/en unknown
- 2018-01-12 WO PCT/US2018/013512 patent/WO2018132669A1/en active Application Filing
-
2019
- 2019-07-12 CL CL2019001951A patent/CL2019001951A1/es unknown
- 2019-08-12 CO CONC2019/0008710A patent/CO2019008710A2/es unknown
- 2019-08-12 ZA ZA2019/05308A patent/ZA201905308B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP3568118B1 (en) | 2022-07-20 |
| CN110300569A (zh) | 2019-10-01 |
| RU2019125245A (ru) | 2021-02-12 |
| CA3049877C (en) | 2023-08-29 |
| WO2018132669A1 (en) | 2018-07-19 |
| MA47269A (fr) | 2019-11-20 |
| CA3049877A1 (en) | 2018-07-19 |
| MX2019008399A (es) | 2019-10-30 |
| AU2018207566A1 (en) | 2019-08-29 |
| BR112019014388A2 (pt) | 2020-02-11 |
| KR20190118155A (ko) | 2019-10-17 |
| JP7074951B2 (ja) | 2022-05-25 |
| CO2019008710A2 (es) | 2020-01-17 |
| US9993578B1 (en) | 2018-06-12 |
| SG11201906344WA (en) | 2019-08-27 |
| RU2019125245A3 (pt) | 2021-05-14 |
| PL3568118T3 (pl) | 2022-11-07 |
| CN110300569B (zh) | 2023-01-03 |
| ES2928429T3 (es) | 2022-11-17 |
| HUE060068T2 (hu) | 2023-01-28 |
| JP2020506747A (ja) | 2020-03-05 |
| EP3568118A4 (en) | 2020-10-28 |
| CL2019001951A1 (es) | 2020-01-31 |
| KR102527685B1 (ko) | 2023-05-02 |
| BR112019014388B1 (pt) | 2023-01-24 |
| ZA201905308B (en) | 2020-05-27 |
| EP3568118A1 (en) | 2019-11-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
| B06W | Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette] | ||
| B25A | Requested transfer of rights approved |
Owner name: LORIA PHARMACEUTICAL, LLC (US) |
|
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 12/01/2018, OBSERVADAS AS CONDICOES LEGAIS |