BR112019004727A2 - método e sistema para revestimento hidrofóbico de chips microfluídicos - Google Patents

método e sistema para revestimento hidrofóbico de chips microfluídicos

Info

Publication number
BR112019004727A2
BR112019004727A2 BR112019004727A BR112019004727A BR112019004727A2 BR 112019004727 A2 BR112019004727 A2 BR 112019004727A2 BR 112019004727 A BR112019004727 A BR 112019004727A BR 112019004727 A BR112019004727 A BR 112019004727A BR 112019004727 A2 BR112019004727 A2 BR 112019004727A2
Authority
BR
Brazil
Prior art keywords
hydrophobic coating
microfluidic chips
microfluidic chip
liquid
discrete flow
Prior art date
Application number
BR112019004727A
Other languages
English (en)
Other versions
BR112019004727B1 (pt
Inventor
John; Larsen
Zheng Xia
Yu Zhou
Original Assignee
Premium Genetics Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Premium Genetics Uk Ltd filed Critical Premium Genetics Uk Ltd
Publication of BR112019004727A2 publication Critical patent/BR112019004727A2/pt
Publication of BR112019004727B1 publication Critical patent/BR112019004727B1/pt

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D129/00—Coating compositions based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal, or ketal radical; Coating compositions based on hydrolysed polymers of esters of unsaturated alcohols with saturated carboxylic acids; Coating compositions based on derivatives of such polymers
    • C09D129/10—Homopolymers or copolymers of unsaturated ethers
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D5/00—Coating compositions, e.g. paints, varnishes or lacquers, characterised by their physical nature or the effects produced; Filling pastes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0636—Focussing flows, e.g. to laminate flows
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14—Process control and prevention of errors
    • B01L2200/141—Preventing contamination, tampering
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/089—Virtual walls for guiding liquids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/12—Specific details about materials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
    • B01L2300/163—Biocompatibility
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
    • B01L2300/165—Specific details about hydrophobic, oleophobic surfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0241—Drop counters; Drop formers
    • B01L3/0268—Drop counters; Drop formers using pulse dispensing or spraying, eg. inkjet type, piezo actuated ejection of droplets from capillaries

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Materials Engineering (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Application Of Or Painting With Fluid Materials (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Micromachines (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

esta revelação refere-se a um método para fornecer um revestimento hidrofóbico em um chip microfluídico que promove o fluxo discreto de pelo menos um líquido. o mesmo inclui aplicar o revestimento hidrofóbico sobre uma área do chip microfluídico. a revelação inclui adicionalmente um chip microfluídico que fornece fluxo discreto de pelo menos um líquido.
BR112019004727-1A 2016-09-12 2017-09-12 Método para fornecer um revestimento hidrofóbico em um chip microfluídico e chip microfluídico BR112019004727B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662393624P 2016-09-12 2016-09-12
US62/393.624 2016-09-12
PCT/IB2017/001289 WO2018047011A2 (en) 2016-09-12 2017-09-12 Method and system for hydrophobic coating of microfluidic chips

Publications (2)

Publication Number Publication Date
BR112019004727A2 true BR112019004727A2 (pt) 2019-05-28
BR112019004727B1 BR112019004727B1 (pt) 2023-10-03

Family

ID=60574639

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112019004727-1A BR112019004727B1 (pt) 2016-09-12 2017-09-12 Método para fornecer um revestimento hidrofóbico em um chip microfluídico e chip microfluídico

Country Status (10)

Country Link
US (1) US10981163B2 (pt)
EP (1) EP3509750A2 (pt)
JP (1) JP7039570B2 (pt)
CN (1) CN109689215B (pt)
AU (1) AU2017323502B2 (pt)
BR (1) BR112019004727B1 (pt)
CA (1) CA3034007C (pt)
MX (1) MX2019002754A (pt)
NZ (1) NZ751869A (pt)
WO (1) WO2018047011A2 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11243494B2 (en) 2002-07-31 2022-02-08 Abs Global, Inc. Multiple laminar flow-based particle and cellular separation with laser steering
US10908066B2 (en) 2010-11-16 2021-02-02 1087 Systems, Inc. Use of vibrational spectroscopy for microfluidic liquid measurement
US8961904B2 (en) 2013-07-16 2015-02-24 Premium Genetics (Uk) Ltd. Microfluidic chip
US11796449B2 (en) 2013-10-30 2023-10-24 Abs Global, Inc. Microfluidic system and method with focused energy apparatus
US11331670B2 (en) 2018-05-23 2022-05-17 Abs Global, Inc. Systems and methods for particle focusing in microchannels
EP4245140A3 (en) 2019-04-18 2024-01-17 ABS Global, Inc. System and process for continuous addition of cryoprotectant
US11628439B2 (en) 2020-01-13 2023-04-18 Abs Global, Inc. Single-sheath microfluidic chip
JP2022049382A (ja) * 2020-09-16 2022-03-29 株式会社エンプラス 流体取扱装置および流体取扱装置の製造方法
CN114929836B (zh) * 2021-12-07 2023-06-27 晶瑞电子材料股份有限公司 一种非金属氧化物膜用缓冲蚀刻液

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6555389B1 (en) 1999-05-11 2003-04-29 Aclara Biosciences, Inc. Sample evaporative control
US6636963B1 (en) * 1999-12-30 2003-10-21 Cardiac Pacemakers, Inc. Quick starting for microprocessor-based system by retrieving a target state memory image and a target state data structure from an image storage medium
CN1330154A (zh) * 2000-06-27 2002-01-09 南京益来基因医学有限公司 细胞微阵列芯片及其制备方法
ATE500051T1 (de) 2001-04-06 2011-03-15 Fluidigm Corp Polymeroberflächenmodifikation
GB0116384D0 (en) * 2001-07-04 2001-08-29 Diagnoswiss Sa Microfluidic chemical assay apparatus and method
US7007710B2 (en) * 2003-04-21 2006-03-07 Predicant Biosciences, Inc. Microfluidic devices and methods
SE0302074D0 (sv) 2003-07-15 2003-07-15 Simon Ekstroem Device and method for analysis of samples using a combined sample treatment and sample carrier device
WO2007021762A2 (en) * 2005-08-09 2007-02-22 The University Of North Carolina At Chapel Hill Methods and materials for fabricating microfluidic devices
US20060105453A1 (en) 2004-09-09 2006-05-18 Brenan Colin J Coating process for microfluidic sample arrays
WO2007008495A2 (en) 2005-07-08 2007-01-18 Velocys Inc. Catalytic reaction process using microchannel technology
US20080014589A1 (en) 2006-05-11 2008-01-17 Link Darren R Microfluidic devices and methods of use thereof
KR100790880B1 (ko) * 2006-07-05 2008-01-02 삼성전자주식회사 자성 비드가 결합되어 있는 소수성 다공성 중합체가 벽면에결합되어 있는 마이크로채널 또는 마이크로챔버를포함하는 미세유동장치 및 그를 이용하는 방법
WO2008126064A2 (en) 2007-04-17 2008-10-23 Nxp B.V. A fluid separation structure and a method of manufacturing a fluid separation structure
KR20120080765A (ko) * 2011-01-10 2012-07-18 삼성전자주식회사 미세유동장치 및 이를 이용한 검체검사방법
US20140287243A1 (en) 2013-03-06 2014-09-25 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Superhydrophobic coatings
JP6480662B2 (ja) * 2013-03-13 2019-03-13 ハウメット コーポレイションＨｏｗｍｅｔ Ｃｏｒｐｏｒａｔｉｏｎ タービン部品のアルミナイジングに用いられるマスカント
US9784664B2 (en) * 2013-09-05 2017-10-10 Bio-Rad Laboratories, Inc. Multidimensional hydrodynamic focusing chamber
WO2015063552A2 (en) * 2013-10-30 2015-05-07 Premium Genetics (Uk) Ltd. Microfluidic system and method with focused energy apparatus

Also Published As

Publication number Publication date
BR112019004727B1 (pt) 2023-10-03
CN109689215B (zh) 2021-12-28
AU2017323502B2 (en) 2022-04-21
JP2019531884A (ja) 2019-11-07
CN109689215A (zh) 2019-04-26
US20180126376A1 (en) 2018-05-10
EP3509750A2 (en) 2019-07-17
CA3034007C (en) 2023-01-17
AU2017323502A1 (en) 2019-04-11
JP7039570B2 (ja) 2022-03-22
MX2019002754A (es) 2019-08-29
NZ751869A (en) 2022-12-23
WO2018047011A2 (en) 2018-03-15
CA3034007A1 (en) 2018-03-15
WO2018047011A3 (en) 2018-05-11
US10981163B2 (en) 2021-04-20

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Legal Events

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B25A Requested transfer of rights approved

Owner name: ABS GLOBAL, INC. (US)

B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

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