BR112018071997A2 - nanopartícula de quitosana-rna, nanopartícula de quitosana-dsrna, composição nutracêutica, crustáceo criado em cativeiro, e método de tratamento ou prevenção de uma doença ou condição em um crustáceo criado em cativeiro associado a um vírus patogênico - Google Patents
nanopartícula de quitosana-rna, nanopartícula de quitosana-dsrna, composição nutracêutica, crustáceo criado em cativeiro, e método de tratamento ou prevenção de uma doença ou condição em um crustáceo criado em cativeiro associado a um vírus patogênicoInfo
- Publication number
- BR112018071997A2 BR112018071997A2 BR112018071997-8A BR112018071997A BR112018071997A2 BR 112018071997 A2 BR112018071997 A2 BR 112018071997A2 BR 112018071997 A BR112018071997 A BR 112018071997A BR 112018071997 A2 BR112018071997 A2 BR 112018071997A2
- Authority
- BR
- Brazil
- Prior art keywords
- chitosan
- captive
- bred
- crustacean
- nanoparticle
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/80—Feeding-stuffs specially adapted for particular animals for aquatic animals, e.g. fish, crustaceans or molluscs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
- A61K48/0025—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the non-active part clearly interacts with the delivered nucleic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0075—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the delivery route, e.g. oral, subcutaneous
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1131—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering N.A.
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/30—Special therapeutic applications
- C12N2320/32—Special delivery means, e.g. tissue-specific
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/80—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
- Y02A40/81—Aquaculture, e.g. of fish
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Polymers & Plastics (AREA)
- Virology (AREA)
- Nanotechnology (AREA)
- Optics & Photonics (AREA)
- Inorganic Chemistry (AREA)
- Insects & Arthropods (AREA)
- Marine Sciences & Fisheries (AREA)
- Animal Husbandry (AREA)
- Birds (AREA)
- Food Science & Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Farming Of Fish And Shellfish (AREA)
- Feed For Specific Animals (AREA)
Abstract
nanopartícula de quitosana-rna, nanopartícula de quitosana-dsrna, composição nutracêutica, crustáceo criado em cativeiro, e método de tratamento ou prevenção de uma doença ou condição em um crustáceo criado em cativeiro associado a um vírus patogênico, fornece nanopartículas, compreendendo quitosana parcialmente desacetilada e ss ou dsrna parcialmente complementar a, ligados a ou, pelo menos, 90% idênticos a mrnas alvos de vírus patogênicos em crustáceos criados em cativeiro, composições e crustáceos aquáticos criados em cativeiro compreendendo os mesmos e métodos para seu uso no tratamento ou prevenção de uma infecção viral na aquicultura
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662327605P | 2016-04-26 | 2016-04-26 | |
US62/327,605 | 2016-04-26 | ||
PCT/IL2017/050475 WO2017187440A1 (en) | 2016-04-26 | 2017-04-26 | Compositions and methods for treating viral infections in shrimps |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112018071997A2 true BR112018071997A2 (pt) | 2019-02-12 |
Family
ID=60160244
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112018071997-8A BR112018071997A2 (pt) | 2016-04-26 | 2017-04-26 | nanopartícula de quitosana-rna, nanopartícula de quitosana-dsrna, composição nutracêutica, crustáceo criado em cativeiro, e método de tratamento ou prevenção de uma doença ou condição em um crustáceo criado em cativeiro associado a um vírus patogênico |
Country Status (7)
Country | Link |
---|---|
US (1) | US10973774B2 (pt) |
CN (1) | CN109689106B (pt) |
BR (1) | BR112018071997A2 (pt) |
EC (1) | ECSP18081039A (pt) |
IL (1) | IL262579A (pt) |
MX (1) | MX2018013122A (pt) |
WO (1) | WO2017187440A1 (pt) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX2018013122A (es) | 2016-04-26 | 2019-03-28 | Viaqua Therapeutics Ltd | Composiciones y procedimientos para tratar infecciones viricas en gambas. |
US20210315214A1 (en) * | 2018-07-03 | 2021-10-14 | Inl - International Iberian Nanotechnology Laboratory | Pesticide |
EP3693024A1 (en) * | 2019-02-05 | 2020-08-12 | Altona Diagnostics GmbH | Control for nucleic acid preparation and/or detection methods |
CN110042100B (zh) * | 2019-03-07 | 2023-03-10 | 汕头大学 | 一种反义核酸AMO-miR-307在制备抗白斑综合症病毒制剂中的应用 |
CN112342300B (zh) * | 2020-11-04 | 2022-12-06 | 浙江省农业科学院 | 红螯螯虾7种组织荧光定量检测内参基因及其筛选方法和应用 |
CN114369607B (zh) * | 2021-06-11 | 2023-10-03 | 中山大学 | 一种用于检测罗氏沼虾病毒MrPV-1的靶基因、引物及其应用 |
CN114369608B (zh) * | 2021-09-24 | 2023-10-13 | 中山大学 | 一种白脚虾小rna病毒基因及其应用 |
WO2023084510A1 (en) | 2021-11-09 | 2023-05-19 | Viaqua Therapeutics Ltd. | Compositions for aquaculturing |
WO2024033948A1 (en) * | 2022-08-11 | 2024-02-15 | Karyotica Biologicals Private Limited | Chimeric dna targeted to white spot syndrome |
CN115948618A (zh) * | 2022-12-28 | 2023-04-11 | 中国海洋大学三亚海洋研究院 | 基于era技术的对虾桃拉综合征病毒快速检测方法及引物与探针组合 |
WO2024142041A1 (en) * | 2022-12-29 | 2024-07-04 | Viaqua Therapeutics Ltd. | Compositions and methods for aquatic microsporidian infection |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0306715D0 (en) * | 2003-03-24 | 2003-04-30 | Novartis Ag | Organic compounds |
JP5183064B2 (ja) * | 2003-07-02 | 2013-04-17 | エムユーエスシー ファウンデイション フォー リサーチ デべロップメント | 甲殻類動物、及び他の無脊椎動物における、dsRNAで誘導された特異的、及び非特異的免疫、及びそこで使用する生物送達媒体 |
US20080194504A1 (en) | 2004-02-06 | 2008-08-14 | Advanced Bionutrition Corporation | Rna-Mediated Interference to Control Disease in Terrestrial and Aquaculture Animals |
CA2515663C (en) * | 2004-08-13 | 2011-10-18 | Katja Heppe - Medical Chitosan | Chitosan-based transport system |
US20100015232A1 (en) | 2006-07-07 | 2010-01-21 | Aarhus Universitet | Nanoparticles for nucleic acid delivery |
ES2376200T3 (es) | 2007-07-06 | 2012-03-09 | Aarhus Universitet | Nanopart�?culas deshidratadas de quitosano. |
WO2009048958A2 (en) * | 2007-10-08 | 2009-04-16 | The Board Of Regents Of The University Of Texas System | Methods and compositions involving chitosan nanoparticles |
BRPI0817895A2 (pt) * | 2007-10-30 | 2015-03-31 | Viscogel Ab | Composição de quitosana reticulável, processo para preparar um hidrogel de quitosana, hidrogel de quitosana, composição farmacêutica, e, agente imunológico |
WO2010088565A1 (en) * | 2009-01-29 | 2010-08-05 | Synedgen, Inc. | Nucleic acid delivery using modified chitosans |
US8916693B2 (en) * | 2009-09-17 | 2014-12-23 | Nektar Therapeutics | Monoconjugated chitosans as delivery agents for small interfering nucleic acids |
AP3284A (en) | 2010-02-24 | 2015-05-31 | Arrowhead Res Corp | Compositions for targeted delivery of SIRNA |
US20120107355A1 (en) * | 2010-10-27 | 2012-05-03 | Harrisvaccines, Inc. | Method of rapidly producing improved vaccines for animals |
CN103889457A (zh) | 2011-05-24 | 2014-06-25 | 波利威乐赞助有限公司 | 使用特异性的基于壳聚糖的纳米复合物用于有效并安全递送siRNA的组合物和方法 |
CN102657880A (zh) * | 2012-05-08 | 2012-09-12 | 浙江大学 | 一种季铵化壳聚糖/siRNA复合粒子及其制备方法 |
CN102908315B (zh) * | 2012-11-02 | 2014-06-04 | 上海现代药物制剂工程研究中心有限公司 | 小分子干扰核糖核酸的壳聚糖纳米粒传递系统及制备方法 |
US20140335192A1 (en) | 2013-05-09 | 2014-11-13 | Kipperman, RM, Ch 7 BK Trustee for Traversa Therap | Delivery of rna interfering agents |
UY35817A (es) | 2013-11-04 | 2015-05-29 | Us Agriculture | ?composiciones y métodos para controlar infestaciones de plagas y parásitos de los artrópodos?. |
US10174317B2 (en) | 2014-02-13 | 2019-01-08 | Synthetic Genomics, Inc. | Recombinant RNA particles and methods of use |
MX2018013122A (es) | 2016-04-26 | 2019-03-28 | Viaqua Therapeutics Ltd | Composiciones y procedimientos para tratar infecciones viricas en gambas. |
AU2018243858A1 (en) | 2017-03-31 | 2019-10-10 | Pebble Labs Usa Inc. | Novel system for the biocontrol of pathogens in aquaculture and other animal systems |
-
2017
- 2017-04-26 MX MX2018013122A patent/MX2018013122A/es unknown
- 2017-04-26 US US16/095,360 patent/US10973774B2/en active Active
- 2017-04-26 BR BR112018071997-8A patent/BR112018071997A2/pt active Search and Examination
- 2017-04-26 CN CN201780039436.3A patent/CN109689106B/zh active Active
- 2017-04-26 WO PCT/IL2017/050475 patent/WO2017187440A1/en active Application Filing
-
2018
- 2018-10-24 IL IL262579A patent/IL262579A/en unknown
- 2018-10-26 EC ECSENADI201881039A patent/ECSP18081039A/es unknown
Also Published As
Publication number | Publication date |
---|---|
US10973774B2 (en) | 2021-04-13 |
WO2017187440A8 (en) | 2017-12-14 |
ECSP18081039A (es) | 2018-11-30 |
CN109689106B (zh) | 2023-01-24 |
CN109689106A (zh) | 2019-04-26 |
US20190175518A1 (en) | 2019-06-13 |
IL262579A (en) | 2018-12-31 |
MX2018013122A (es) | 2019-03-28 |
WO2017187440A1 (en) | 2017-11-02 |
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