BR112018069072A2 - método para determinar o nível total de carbonilação e kit para levar a cabo o método - Google Patents

método para determinar o nível total de carbonilação e kit para levar a cabo o método

Info

Publication number
BR112018069072A2
BR112018069072A2 BR112018069072A BR112018069072A BR112018069072A2 BR 112018069072 A2 BR112018069072 A2 BR 112018069072A2 BR 112018069072 A BR112018069072 A BR 112018069072A BR 112018069072 A BR112018069072 A BR 112018069072A BR 112018069072 A2 BR112018069072 A2 BR 112018069072A2
Authority
BR
Brazil
Prior art keywords
determining
kit
carrying
carbonylation level
total carbonylation
Prior art date
Application number
BR112018069072A
Other languages
English (en)
Inventor
Mah Anna
Schoeneich Christian
Gao Di
A Gennaro Lynn
Yang Yi
Original Assignee
Genentech Inc
Univ Kansas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc, Univ Kansas filed Critical Genentech Inc
Publication of BR112018069072A2 publication Critical patent/BR112018069072A2/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/583—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with non-fluorescent dye label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2440/00—Post-translational modifications [PTMs] in chemical analysis of biological material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

a descrição refere-se a um método e kits para determinar o nível de carbonilação total num polipeptídeo.
BR112018069072A 2016-05-19 2017-05-18 método para determinar o nível total de carbonilação e kit para levar a cabo o método BR112018069072A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662338605P 2016-05-19 2016-05-19
PCT/US2017/033371 WO2017201312A1 (en) 2016-05-19 2017-05-18 Assay for determining the total carbonylation level on a polypeptide

Publications (1)

Publication Number Publication Date
BR112018069072A2 true BR112018069072A2 (pt) 2019-01-22

Family

ID=59014741

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112018069072A BR112018069072A2 (pt) 2016-05-19 2017-05-18 método para determinar o nível total de carbonilação e kit para levar a cabo o método

Country Status (12)

Country Link
US (1) US11371999B2 (pt)
EP (1) EP3458855A1 (pt)
JP (1) JP6970122B2 (pt)
KR (1) KR102408263B1 (pt)
CN (1) CN109154597B (pt)
AU (1) AU2017267726B2 (pt)
BR (1) BR112018069072A2 (pt)
CA (1) CA3013668A1 (pt)
IL (1) IL262322B2 (pt)
MX (1) MX2018013673A (pt)
SG (1) SG11201807313PA (pt)
WO (1) WO2017201312A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113138206B (zh) * 2021-03-04 2022-04-19 宁波大学 一种鉴别氨基酸的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5362852A (en) * 1991-09-27 1994-11-08 Pfizer Inc. Modified peptide derivatives conjugated at 2-hydroxyethylamine moieties
CA2616677A1 (en) 2005-07-27 2007-02-08 F. Hoffmann-La Roche Ag Cathepsin k inhibitors
US20090004684A1 (en) * 2007-05-23 2009-01-01 Claudia Susanne Maier Compositions and Methods for Detection and Quantification of Protein Oxidation
WO2009129472A2 (en) * 2008-04-18 2009-10-22 University Of Pittsburgh Of The Commonwealth System Of Higher Education Methods of labeling biological samples
US20100105102A1 (en) * 2008-10-22 2010-04-29 Reveal Sciences, Llc Device, method and apparatus for analyzing skin and hair
US20100254581A1 (en) * 2009-04-07 2010-10-07 Reveal Sciences, Llc Device, method, and apparatus for biological testing with a mobile device
EP2510361A4 (en) * 2009-12-11 2013-07-17 Purdue Research Foundation DETECTION OF OXIDIZED POLYPEPTIDES
EP2721411B1 (en) * 2011-06-20 2018-04-18 Université Pierre et Marie Curie (Paris 6) A method for detecting and/or quantifying carbonylated proteins
CN104020246A (zh) * 2014-06-24 2014-09-03 上海大学 同时检测大气中多种挥发性痕量羰基化合物的方法

Also Published As

Publication number Publication date
CA3013668A1 (en) 2017-11-23
KR20190008853A (ko) 2019-01-25
CN109154597B (zh) 2022-06-24
JP6970122B2 (ja) 2021-11-24
SG11201807313PA (en) 2018-09-27
US20190219590A1 (en) 2019-07-18
CN109154597A (zh) 2019-01-04
AU2017267726A1 (en) 2018-08-16
JP2019521328A (ja) 2019-07-25
US11371999B2 (en) 2022-06-28
AU2017267726B2 (en) 2023-09-14
EP3458855A1 (en) 2019-03-27
KR102408263B1 (ko) 2022-06-10
WO2017201312A1 (en) 2017-11-23
IL262322A (en) 2018-11-29
MX2018013673A (es) 2019-05-02
IL262322B2 (en) 2024-01-01
IL262322B1 (en) 2023-09-01

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Legal Events

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B350 Update of information on the portal [chapter 15.35 patent gazette]
B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]