BR112018015255A2 - extrato de streptococcus uberis como um agente imunogênico - Google Patents
extrato de streptococcus uberis como um agente imunogênicoInfo
- Publication number
- BR112018015255A2 BR112018015255A2 BR112018015255-2A BR112018015255A BR112018015255A2 BR 112018015255 A2 BR112018015255 A2 BR 112018015255A2 BR 112018015255 A BR112018015255 A BR 112018015255A BR 112018015255 A2 BR112018015255 A2 BR 112018015255A2
- Authority
- BR
- Brazil
- Prior art keywords
- immunogenic agent
- biofilm
- agent
- extract
- uberis
- Prior art date
Links
- 230000002163 immunogen Effects 0.000 title abstract 4
- 241000194054 Streptococcus uberis Species 0.000 title abstract 2
- 229940115922 streptococcus uberis Drugs 0.000 title abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 5
- 230000002265 prevention Effects 0.000 abstract 3
- 229960005486 vaccine Drugs 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- 150000007513 acids Chemical class 0.000 abstract 2
- 208000015181 infectious disease Diseases 0.000 abstract 2
- 208000004396 mastitis Diseases 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 241000194017 Streptococcus Species 0.000 abstract 1
- 241000194022 Streptococcus sp. Species 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002255 vaccination Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/36—Adaptation or attenuation of cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Cell Biology (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
a presente invenção refere-se a um extrato de streptococcus uberis como um agente imunogênico. refere-se também a um processo para a obtenção do referido agente que compreende a incubação de uma cepa de s. uberis produtora de biofilme para obtenção de um biofilme e tratamento térmico do biofilme obtido. refere-se também a uma composição farmacêutica que compreende ácidos teicoicos, preferivelmente ácidos lipoteicoicos, para uso na prevenção e/ou tratamento de mastite e/ou infecções causadas por streptococcus sp ou por bactérias produtoras de biofilme. a presente invenção também se refere a uma vacina que compreende o referido agente imunogênico e a referida vacina e agente imunogênico para uso na prevenção e/ou tratamento de infecções causadas por streptococcus sp., especialmente na prevenção e/ou tratamento de mastite causada por s. uberis. refere-se também a um kit de vacinação que compreende o referido agente ou vacina
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16382060 | 2016-02-15 | ||
| EP16382060.8 | 2016-02-15 | ||
| PCT/EP2017/053306 WO2017140683A2 (en) | 2016-02-15 | 2017-02-14 | Streptococcus uberis extract as an immunogenic agent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112018015255A2 true BR112018015255A2 (pt) | 2018-12-18 |
Family
ID=55646514
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112018015255-2A BR112018015255A2 (pt) | 2016-02-15 | 2017-02-14 | extrato de streptococcus uberis como um agente imunogênico |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US10946085B2 (pt) |
| EP (1) | EP3417049B1 (pt) |
| JP (1) | JP6839199B2 (pt) |
| KR (1) | KR20180108619A (pt) |
| AU (1) | AU2017220528A1 (pt) |
| BR (1) | BR112018015255A2 (pt) |
| CA (1) | CA3012419A1 (pt) |
| ES (1) | ES2960326T3 (pt) |
| MX (1) | MX2018009048A (pt) |
| PL (1) | PL3417049T3 (pt) |
| WO (1) | WO2017140683A2 (pt) |
| ZA (1) | ZA201805039B (pt) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2023048111A1 (pt) | 2021-09-21 | 2023-03-30 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60243024A (ja) * | 1983-12-29 | 1985-12-03 | Kitasato Inst:The | ストレプトコツカス・サンギス感染症予防用ワクチン，診断用抗原および抗体 |
| CA2059693C (en) * | 1991-01-28 | 2003-08-19 | Peter J. Kniskern | Polysaccharide antigens from streptococcus pneumoniae |
| CN1226414C (zh) | 1995-06-08 | 2005-11-09 | 萨斯喀彻温大学 | 乳房链球菌的camp因子 |
| ES2273861T3 (es) | 2000-06-12 | 2007-05-16 | University Of Saskatchewan | Inmunizacion de ganado vacuno lechero con proteina gapc frente a infecciones por streptococcus. |
| US20070231335A1 (en) * | 2005-07-20 | 2007-10-04 | Bruce Beutler | Compositions and methods for treating Gram positive bacterial infection in a mammalian subject |
| ES2657392T3 (es) | 2006-09-26 | 2018-03-05 | Infectious Disease Research Institute | Composición de vacuna que contiene un adyuvante sintético |
| WO2008098172A1 (en) * | 2007-02-09 | 2008-08-14 | Montana State University | Enhancement of innate resistance to infection |
| GB0818231D0 (en) | 2008-10-06 | 2008-11-12 | Univ Nottingham | Composition |
| CA2766418C (en) * | 2009-06-22 | 2016-03-29 | Wyeth Llc | Compositions and methods for preparing staphylococcus aureus serotype 5 and 8 capsular polysaccharide conjugate immunogenic compositions |
| US9415062B2 (en) * | 2011-03-03 | 2016-08-16 | Burim N. Ametaj | Use of bacterial endotoxins and lipoteichoic acids to improve postpartal health and productivity of dairy cows and their newborns |
| CA2834438A1 (en) * | 2011-05-12 | 2012-11-15 | Intervet International B.V. | Treatment of mastitis |
| BR112013032675A2 (pt) * | 2011-06-19 | 2017-08-08 | Vaxine Pty Ltd | composição adjuvante de vacina compreendendo partículas de inulina |
| CA2924526A1 (en) | 2013-09-19 | 2015-03-26 | Paul Joseph Dominowski | Water-in-oil emulsions comprising immunostimulatory oligonucleotides |
-
2017
- 2017-02-14 ES ES17704038T patent/ES2960326T3/es active Active
- 2017-02-14 WO PCT/EP2017/053306 patent/WO2017140683A2/en active Application Filing
- 2017-02-14 JP JP2018538841A patent/JP6839199B2/ja active Active
- 2017-02-14 MX MX2018009048A patent/MX2018009048A/es unknown
- 2017-02-14 KR KR1020187021575A patent/KR20180108619A/ko unknown
- 2017-02-14 CA CA3012419A patent/CA3012419A1/en active Pending
- 2017-02-14 BR BR112018015255-2A patent/BR112018015255A2/pt active Search and Examination
- 2017-02-14 PL PL17704038.3T patent/PL3417049T3/pl unknown
- 2017-02-14 US US16/075,092 patent/US10946085B2/en active Active
- 2017-02-14 AU AU2017220528A patent/AU2017220528A1/en not_active Abandoned
- 2017-02-14 EP EP17704038.3A patent/EP3417049B1/en active Active
-
2018
- 2018-07-26 ZA ZA2018/05039A patent/ZA201805039B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2017140683A3 (en) | 2017-10-12 |
| MX2018009048A (es) | 2019-03-28 |
| JP6839199B2 (ja) | 2021-03-03 |
| EP3417049B1 (en) | 2023-08-16 |
| KR20180108619A (ko) | 2018-10-04 |
| AU2017220528A1 (en) | 2018-08-09 |
| US20190038736A1 (en) | 2019-02-07 |
| ZA201805039B (en) | 2020-05-27 |
| WO2017140683A2 (en) | 2017-08-24 |
| ES2960326T3 (es) | 2024-03-04 |
| EP3417049A2 (en) | 2018-12-26 |
| CA3012419A1 (en) | 2017-08-24 |
| JP2019504623A (ja) | 2019-02-21 |
| PL3417049T3 (pl) | 2024-02-19 |
| US10946085B2 (en) | 2021-03-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
| B06W | Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] |