BR112017025533A2 - método para tratar câncer em um paciente humano - Google Patents
método para tratar câncer em um paciente humanoInfo
- Publication number
- BR112017025533A2 BR112017025533A2 BR112017025533A BR112017025533A BR112017025533A2 BR 112017025533 A2 BR112017025533 A2 BR 112017025533A2 BR 112017025533 A BR112017025533 A BR 112017025533A BR 112017025533 A BR112017025533 A BR 112017025533A BR 112017025533 A2 BR112017025533 A2 BR 112017025533A2
- Authority
- BR
- Brazil
- Prior art keywords
- human patient
- treat cancer
- combination therapies
- cancer
- cpg
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7115—Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7125—Nucleic acids or oligonucleotides having modified internucleoside linkage, i.e. other than 3'-5' phosphodiesters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Abstract
a presente descrição descreve terapias de combinação compreendendo um anticorpo anti-il-10 ou fragmento de ligação de antígeno do mesmo e um oligonucleotídeo tipo cpg-c, e o uso das terapias de combinação para o tratamento de câncer.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562168470P | 2015-05-29 | 2015-05-29 | |
US201562169321P | 2015-06-01 | 2015-06-01 | |
PCT/US2016/034285 WO2016196178A1 (en) | 2015-05-29 | 2016-05-26 | Combination of an anti-il-10 antibody and a cpg-c type oligonucleotide for treating cancer |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112017025533A2 true BR112017025533A2 (pt) | 2018-08-07 |
Family
ID=57442233
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112017025533A BR112017025533A2 (pt) | 2015-05-29 | 2016-05-26 | método para tratar câncer em um paciente humano |
Country Status (12)
Country | Link |
---|---|
US (1) | US20180161427A1 (pt) |
EP (1) | EP3302554A4 (pt) |
JP (1) | JP2018516252A (pt) |
KR (1) | KR20180014010A (pt) |
CN (1) | CN107949399A (pt) |
AU (1) | AU2016271023A1 (pt) |
BR (1) | BR112017025533A2 (pt) |
CA (1) | CA2986232A1 (pt) |
MA (1) | MA44700A (pt) |
MX (1) | MX2017015311A (pt) |
RU (1) | RU2017145559A (pt) |
WO (1) | WO2016196178A1 (pt) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8158768B2 (en) | 2002-12-23 | 2012-04-17 | Dynavax Technologies Corporation | Immunostimulatory sequence oligonucleotides and methods of using the same |
JP2017537619A (ja) | 2014-11-21 | 2017-12-21 | ノースウェスタン ユニバーシティ | 球状核酸ナノ粒子複合体の配列特異的細胞内取込 |
RU2017145940A (ru) * | 2015-05-29 | 2019-07-02 | Дайнэвокс Текнолоджиз Корпорейшн | Внутрилегочное введение полинуклеотидных агонистов толл-подобного рецептора 9 для лечения рака легких |
EP3302501B1 (en) | 2015-05-29 | 2021-09-22 | Merck Sharp & Dohme Corp. | Combination of a pd-1 antagonist and cpg-c type oligonucleotide for treating cancer |
US11364304B2 (en) | 2016-08-25 | 2022-06-21 | Northwestern University | Crosslinked micellar spherical nucleic acids |
WO2018209270A1 (en) | 2017-05-11 | 2018-11-15 | Northwestern University | Adoptive cell therapy using spherical nucleic acids (snas) |
WO2019234221A1 (en) | 2018-06-08 | 2019-12-12 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for stratification and treatment of a patient suffering from chronic lymphocytic leukemia |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW200303759A (en) * | 2001-11-27 | 2003-09-16 | Schering Corp | Methods for treating cancer |
EP1575977B1 (en) * | 2002-12-23 | 2009-09-09 | Dynavax Technologies Corporation | Immunostimulatory sequence oligonucleotides and methods of using the same |
PE20090047A1 (es) * | 2003-11-10 | 2009-01-26 | Schering Corp | Anticuerpo recombinante humanizado anti-interleuquina 10 |
WO2006086798A2 (en) * | 2005-02-08 | 2006-08-17 | Board Of Regents, The University Of Texas System | Compositions and methods involving mda-7 for the treatment of cancer |
WO2007107349A1 (en) * | 2006-03-22 | 2007-09-27 | Apogenix Gmbh | Antibody specific for human il-4 for the treament of cancer |
JP2009016596A (ja) * | 2007-07-05 | 2009-01-22 | Elpida Memory Inc | 半導体装置及び半導体装置の製造方法 |
EP2190440A1 (en) * | 2007-08-13 | 2010-06-02 | Pfizer Inc. | Combination motif immune stimulatory oligonucleotides with improved activity |
-
2016
- 2016-05-26 RU RU2017145559A patent/RU2017145559A/ru not_active Application Discontinuation
- 2016-05-26 AU AU2016271023A patent/AU2016271023A1/en not_active Abandoned
- 2016-05-26 KR KR1020177037186A patent/KR20180014010A/ko unknown
- 2016-05-26 CA CA2986232A patent/CA2986232A1/en not_active Abandoned
- 2016-05-26 EP EP16804055.8A patent/EP3302554A4/en not_active Withdrawn
- 2016-05-26 WO PCT/US2016/034285 patent/WO2016196178A1/en active Application Filing
- 2016-05-26 BR BR112017025533A patent/BR112017025533A2/pt not_active Application Discontinuation
- 2016-05-26 US US15/577,377 patent/US20180161427A1/en not_active Abandoned
- 2016-05-26 MX MX2017015311A patent/MX2017015311A/es unknown
- 2016-05-26 JP JP2017561618A patent/JP2018516252A/ja active Pending
- 2016-05-26 CN CN201680043447.4A patent/CN107949399A/zh active Pending
- 2016-05-26 MA MA044700A patent/MA44700A/fr unknown
Also Published As
Publication number | Publication date |
---|---|
RU2017145559A (ru) | 2019-07-03 |
US20180161427A1 (en) | 2018-06-14 |
JP2018516252A (ja) | 2018-06-21 |
MA44700A (fr) | 2019-02-27 |
KR20180014010A (ko) | 2018-02-07 |
CN107949399A (zh) | 2018-04-20 |
MX2017015311A (es) | 2018-06-19 |
CA2986232A1 (en) | 2016-12-08 |
AU2016271023A1 (en) | 2017-11-30 |
EP3302554A1 (en) | 2018-04-11 |
EP3302554A4 (en) | 2019-02-27 |
WO2016196178A1 (en) | 2016-12-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |