SV2017005380A - Tratamientos conjuntos con anticuerpos anti cd40 - Google Patents
Tratamientos conjuntos con anticuerpos anti cd40Info
- Publication number
- SV2017005380A SV2017005380A SV2017005380A SV2017005380A SV2017005380A SV 2017005380 A SV2017005380 A SV 2017005380A SV 2017005380 A SV2017005380 A SV 2017005380A SV 2017005380 A SV2017005380 A SV 2017005380A SV 2017005380 A SV2017005380 A SV 2017005380A
- Authority
- SV
- El Salvador
- Prior art keywords
- treatments
- antibodies
- joint
- joint treatments
- antigen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
LA PRESENTE INVENCIÓN SE REFIERE A TRATAMIENTOS CONJUNTOS PARA TRATAR UN TUMOR SÓLIDO EN UN SUJETO. LOS TRATAMIENTOS CONJUNTOS COMPRENDEN (A) UN ANTICUERPO, O LA PORCIÓN DE FIJACIÓN AL ANTÍGENO DE ESTE, QUE SE FIJA ESPECÍFICAMENTE A CD40, Y (B) UN AGENTE INMUNOTERAPÉUTICO ADICIONAL CON EFICACIA EN EL TRATAMIENTO DEL CÁNCER, EN DONDE EL AGENTE NO ES UN ANTICUERPO ANTI-CD4O NI EL FRAGMENTO DE FIJACIÓN AL ANTÍGENO DE ESTE. LA INVENCIÓN TAMBIÉN SE REFIERE A KITS Y MÉTODOS PARA USAR TALES TRATAMIENTOS
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1414270.7A GB201414270D0 (en) | 2014-08-12 | 2014-08-12 | Antibodies |
GB201422614 | 2014-12-18 | ||
GBGB1507541.9A GB201507541D0 (en) | 2015-05-01 | 2015-05-01 | Antibodies |
Publications (1)
Publication Number | Publication Date |
---|---|
SV2017005380A true SV2017005380A (es) | 2018-09-14 |
Family
ID=53836090
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SV2017005380A SV2017005380A (es) | 2014-08-12 | 2017-02-07 | Tratamientos conjuntos con anticuerpos anti cd40 |
Country Status (25)
Country | Link |
---|---|
US (3) | US11149090B2 (es) |
EP (2) | EP3552665A3 (es) |
JP (1) | JP6654187B2 (es) |
KR (1) | KR102443258B1 (es) |
CN (2) | CN114099671A (es) |
AU (1) | AU2015303164B2 (es) |
CA (1) | CA2957146A1 (es) |
CL (1) | CL2017000335A1 (es) |
CO (1) | CO2017001317A2 (es) |
CR (1) | CR20170096A (es) |
DK (1) | DK3180087T3 (es) |
EA (1) | EA201790339A1 (es) |
EC (1) | ECSP17008984A (es) |
ES (1) | ES2725463T3 (es) |
IL (1) | IL250512B (es) |
MA (1) | MA47472A (es) |
MX (1) | MX2017001864A (es) |
NI (1) | NI201700015A (es) |
NZ (1) | NZ729270A (es) |
PE (1) | PE20170680A1 (es) |
PH (1) | PH12017500229A1 (es) |
SG (1) | SG11201701070WA (es) |
SV (1) | SV2017005380A (es) |
UA (1) | UA119783C2 (es) |
WO (1) | WO2016023960A1 (es) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20190122889A (ko) | 2011-04-29 | 2019-10-30 | 아펙시젠, 인코포레이티드 | 항-cd40 항체 및 사용 방법 |
JP6367836B2 (ja) | 2013-02-07 | 2018-08-01 | ザ ジェネラル ホスピタル コーポレイション | T制御性細胞の増殖または枯渇方法 |
AR097584A1 (es) | 2013-09-12 | 2016-03-23 | Hoffmann La Roche | Terapia de combinación de anticuerpos contra el csf-1r humano y anticuerpos contra el pd-l1 humano |
JP6502959B2 (ja) | 2013-12-12 | 2019-04-17 | 上海恒瑞医薬有限公司 | Pd−1抗体、その抗原結合性断片及びそれらの医学的使用 |
TWI754621B (zh) | 2015-11-18 | 2022-02-11 | 美商默沙東藥廠 | Pd1及/或 lag3結合劑 |
MX2018007089A (es) | 2015-12-14 | 2019-01-30 | Macrogenics Inc | Moleculas biespecificas que tienen inmunorreactividad con pd-1 y ctla-4, y metodos de uso de las mismas. |
CN109476745B (zh) * | 2016-05-13 | 2023-11-24 | 综合医院公司 | 拮抗性抗肿瘤坏死因子受体超家族抗体 |
BR112018076281A2 (pt) | 2016-06-20 | 2019-03-26 | Kymab Limited | imunocitocina, uso de uma imunocitocina, método, composição farmacêutica, método para tratar uma doença proliferativa em um animal, ácido nucleico, vetor, hospedeiro e anticorpo ou fragmento do mesmo |
CN117247458A (zh) | 2016-07-14 | 2023-12-19 | 健玛保 | 针对cd40和cd137的多特异性抗体 |
EP3504239B1 (en) | 2016-08-25 | 2024-05-29 | F. Hoffmann-La Roche AG | Intermittent dosing of an anti-csf-1r antibody in combination with macrophage activating agent |
WO2018078620A1 (en) | 2016-10-25 | 2018-05-03 | Urogen Pharma Ltd. | Immunomodulating treatments of body cavities |
JP2019534292A (ja) * | 2016-11-02 | 2019-11-28 | アペクシジェン, インコーポレイテッド | 組み合わせた抗cd40抗体および使用方法 |
EP3558360A1 (en) | 2016-12-22 | 2019-10-30 | F. Hoffmann-La Roche AG | Treatment of tumors with an anti-csf-1r antibody in combination with an anti-pd-l1 antibody after failure of anti-pd-l1/pd1 treatment |
JP7181878B2 (ja) * | 2017-01-13 | 2022-12-01 | タイチョウ ハンチョン バイオファーマシューティクス インコーポレイテッド | Pd-1に対するモノクローナル抗体及びその適用 |
EP3589324A1 (en) * | 2017-03-03 | 2020-01-08 | Janssen Biotech, Inc. | Co-therapy comprising a small molecule csf-1r inhibitor and an agonistic antibody that specifically binds cd40 for the treatment of cancer |
EP3675877A1 (en) | 2017-08-31 | 2020-07-08 | Multimmune GmbH | Hsp70 based combination therapy |
KR20210038839A (ko) * | 2018-03-13 | 2021-04-08 | 히버셀, 인크. | 베타 글루칸 및 cd40 효능제 조합 면역요법 |
EP3807320A4 (en) * | 2018-06-12 | 2022-03-23 | BioNTech US Inc. | POLYTHERAPY INCLUDING A VACCINE BASED ON NEO ANTIGENS |
JP2021528393A (ja) | 2018-06-15 | 2021-10-21 | フラグシップ パイオニアリング イノベーションズ ブイ,インコーポレーテッド | 後細胞シグナル伝達因子の調節による免疫活性の上昇 |
KR20210095891A (ko) | 2018-11-23 | 2021-08-03 | 스트라이크 파마 아베 | 이중 특이적 접합체 |
TW202039558A (zh) * | 2018-11-30 | 2020-11-01 | 大陸商江蘇恆瑞醫藥股份有限公司 | 抗cd40抗體、其抗原結合片段及其醫藥用途 |
EP3962493A2 (en) | 2019-05-03 | 2022-03-09 | Flagship Pioneering Innovations V, Inc. | Methods of modulating immune activity/level of irf or sting or of treating cancer, comprising the administration of a sting modulator and/or purinergic receptor modulator or postcellular signaling factor |
MA56027A (fr) * | 2019-05-28 | 2022-04-06 | Janssen Biotech Inc | Procédé de fourniture d'une administration sûre d'un anticorps anti-cd40 |
WO2021048135A1 (en) | 2019-09-09 | 2021-03-18 | Basilea Pharmaceutica International AG | Pharmaceutical combinations comprising a furazanobenzimidazoles and a cd40 agonist for use in the treatment of neoplastic diseases |
US20230114107A1 (en) | 2019-12-17 | 2023-04-13 | Flagship Pioneering Innovations V, Inc. | Combination anti-cancer therapies with inducers of iron-dependent cellular disassembly |
CN114981435A (zh) * | 2019-12-27 | 2022-08-30 | 因特欧力多公司 | 用于治疗癌症的抗癌免疫治疗组合物 |
GB202008003D0 (en) | 2020-05-28 | 2020-07-15 | Quine Medical Ab | Anti-CD40 antibody |
CA3184366A1 (en) | 2020-06-29 | 2022-01-06 | Darby Rye Schmidt | Viruses engineered to promote thanotransmission and their use in treating cancer |
WO2022036495A1 (en) | 2020-08-17 | 2022-02-24 | Utc Therapeutics Inc. | Lymphocytes-antigen presenting cells co-stimulators and uses thereof |
KR20230165276A (ko) | 2021-03-31 | 2023-12-05 | 플래그쉽 파이어니어링 이노베이션스 브이, 인크. | 타노트랜스미션 폴리펩티드 및 암의 치료에서의 이의 용도 |
EP4363059A1 (en) | 2021-06-29 | 2024-05-08 | Flagship Pioneering Innovations V, Inc. | Immune cells engineered to promote thanotransmission and uses thereof |
EP4415757A1 (en) * | 2021-10-15 | 2024-08-21 | The Rockefeller University | Combination of anti-cd40 antibody and il-15 for treating cancer |
WO2023247050A1 (en) | 2022-06-23 | 2023-12-28 | Alligator Bioscience Ab | Combination therapies |
US20240174732A1 (en) | 2022-10-05 | 2024-05-30 | Flagship Pioneering Innovations V, Inc. | Nucleic acid molecules encoding trif and additional polypeptides and their use in treating cancer |
US20240269251A1 (en) | 2023-01-09 | 2024-08-15 | Flagship Pioneering Innovations V, Inc. | Genetic switches and their use in treating cancer |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6051228A (en) | 1998-02-19 | 2000-04-18 | Bristol-Myers Squibb Co. | Antibodies against human CD40 |
WO2001083755A2 (en) | 2000-04-28 | 2001-11-08 | La Jolla Institute For Allergy And Immunology | Human anti-cd40 antibodies and methods of making and using same |
AU2002234572B2 (en) | 2000-12-12 | 2006-07-06 | Alligator Bioscience Ab | A method for in vitro molecular evolution of protein function |
CA2658221C (en) | 2001-04-27 | 2012-11-27 | Kyowa Hakko Kirin Co., Ltd. | Anti-cd40 monoclonal antibody |
AR039067A1 (es) | 2001-11-09 | 2005-02-09 | Pfizer Prod Inc | Anticuerpos para cd40 |
US7432063B2 (en) | 2002-02-14 | 2008-10-07 | Kalobios Pharmaceuticals, Inc. | Methods for affinity maturation |
US20040110226A1 (en) | 2002-03-01 | 2004-06-10 | Xencor | Antibody optimization |
DE60312507T3 (de) | 2002-05-17 | 2011-08-18 | Alligator Bioscience Ab | Eine methode zur in vitro molekularen evolution der proteinfunktion |
CN101001872A (zh) * | 2004-04-16 | 2007-07-18 | 宏观基因有限公司 | FcγRIIB-特异性抗体及其使用方法 |
AU2005323515A1 (en) | 2004-04-27 | 2006-07-13 | Novartis Vaccines And Diagnostics, Inc. | Antagonist anti-CD40 monoclonal antibodies and methods for their use |
BRPI0610235B8 (pt) | 2005-05-09 | 2021-05-25 | Squibb & Sons Llc | anticorpos monoclonais geneticamente modificados e diferentes daqueles encontrados na natureza, ou porção de ligação ao antígeno dos mesmos, usos terapêuticos dos mesmos, composições, imunoconjugado, molécula biespecífica compreendendo os mesmos, molécula de ácido nucléico e vetor de expressão |
DE602006017690D1 (de) | 2005-05-26 | 2010-12-02 | Genentech Inc | Humanisierte antikörper gegen cd40 und verfahren zu ihrer anwendung |
GB0620894D0 (en) * | 2006-10-20 | 2006-11-29 | Univ Southampton | Human immune therapies using a CD27 agonist alone or in combination with other immune modulators |
AU2009206506B2 (en) | 2008-01-23 | 2013-01-10 | Xencor, Inc. | Optimized CD40 antibodies and methods of using the same |
CA2735421A1 (en) | 2008-08-29 | 2010-03-04 | Academisch Ziekenhuis Leiden H.O.D.N. Lumc | Delivery of a cd40 agonist to a tumor draining lymph node of a subject |
TW201840336A (zh) | 2011-08-01 | 2018-11-16 | 美商建南德克公司 | 利用pd-1軸結合拮抗劑及mek抑制劑治療癌症之方法 |
GB201115280D0 (en) | 2011-09-05 | 2011-10-19 | Alligator Bioscience Ab | Antibodies, uses and methods |
AR090263A1 (es) | 2012-03-08 | 2014-10-29 | Hoffmann La Roche | Terapia combinada de anticuerpos contra el csf-1r humano y las utilizaciones de la misma |
US10533054B2 (en) * | 2013-01-31 | 2020-01-14 | Thomas Jefferson University | Agonist fusion protein for CD40 and OX40 and methods of stimulating the immune system |
EA201600474A1 (ru) | 2013-12-20 | 2016-11-30 | Ф. Хоффманн-Ля Рош Аг | Комбинированная терапия с использованием антитела к ang2 и агониста cd40 |
TWI693232B (zh) | 2014-06-26 | 2020-05-11 | 美商宏觀基因股份有限公司 | 與pd-1和lag-3具有免疫反應性的共價結合的雙抗體和其使用方法 |
US10478494B2 (en) | 2015-04-03 | 2019-11-19 | Astex Therapeutics Ltd | FGFR/PD-1 combination therapy for the treatment of cancer |
EA201792273A1 (ru) | 2015-04-17 | 2018-04-30 | Бристол-Маерс Сквибб Компани | Композиции, содержащие комбинацию анти-pd-1 антитела и другого антитела |
PL3303395T3 (pl) | 2015-05-29 | 2020-05-18 | Abbvie Inc. | Przeciwciała anty-cd40 i ich zastosowania |
JP7350467B2 (ja) | 2015-06-29 | 2023-09-26 | ブリストル-マイヤーズ スクイブ カンパニー | Cd40に対する抗体 |
UY36757A (es) | 2015-06-29 | 2016-12-30 | Bristol Myers Squibb Company Una Corporación Del Estado De Delaware | Anticuerpos monoclonales murinos contra cd40 con actividad agonista mejorada |
-
2015
- 2015-08-12 DK DK15750051.3T patent/DK3180087T3/da active
- 2015-08-12 EP EP19161728.1A patent/EP3552665A3/en active Pending
- 2015-08-12 EP EP15750051.3A patent/EP3180087B1/en active Active
- 2015-08-12 UA UAA201701452A patent/UA119783C2/uk unknown
- 2015-08-12 EA EA201790339A patent/EA201790339A1/ru unknown
- 2015-08-12 JP JP2017507739A patent/JP6654187B2/ja active Active
- 2015-08-12 ES ES15750051T patent/ES2725463T3/es active Active
- 2015-08-12 SG SG11201701070WA patent/SG11201701070WA/en unknown
- 2015-08-12 PE PE2017000203A patent/PE20170680A1/es unknown
- 2015-08-12 CN CN202111420044.6A patent/CN114099671A/zh active Pending
- 2015-08-12 AU AU2015303164A patent/AU2015303164B2/en active Active
- 2015-08-12 KR KR1020177005821A patent/KR102443258B1/ko active IP Right Grant
- 2015-08-12 US US15/329,402 patent/US11149090B2/en active Active
- 2015-08-12 NZ NZ729270A patent/NZ729270A/en unknown
- 2015-08-12 CN CN201580043161.1A patent/CN106573981A/zh active Pending
- 2015-08-12 WO PCT/EP2015/068598 patent/WO2016023960A1/en active Application Filing
- 2015-08-12 CR CR20170096A patent/CR20170096A/es unknown
- 2015-08-12 CA CA2957146A patent/CA2957146A1/en active Pending
- 2015-08-12 MX MX2017001864A patent/MX2017001864A/es unknown
- 2015-08-12 MA MA047472A patent/MA47472A/fr unknown
-
2017
- 2017-02-07 PH PH12017500229A patent/PH12017500229A1/en unknown
- 2017-02-07 SV SV2017005380A patent/SV2017005380A/es unknown
- 2017-02-08 IL IL250512A patent/IL250512B/en unknown
- 2017-02-09 CL CL2017000335A patent/CL2017000335A1/es unknown
- 2017-02-09 NI NI201700015A patent/NI201700015A/es unknown
- 2017-02-10 CO CONC2017/0001317A patent/CO2017001317A2/es unknown
- 2017-02-10 EC ECIEPI20178984A patent/ECSP17008984A/es unknown
-
2021
- 2021-09-15 US US17/475,592 patent/US20210403589A1/en not_active Abandoned
-
2023
- 2023-12-13 US US18/538,429 patent/US20240228643A9/en active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SV2017005380A (es) | Tratamientos conjuntos con anticuerpos anti cd40 | |
CO2018000809A2 (es) | Anticuerpos para cd40 | |
CL2017000285A1 (es) | Terapia combinada para el tratamiento de un paramixovirus | |
EA201990296A1 (ru) | Антитела против siglec-7 для лечения рака | |
ECSP17005649A (es) | Anticuerpos anti-tau humanizados | |
BR112018013731A2 (pt) | combinações anti-egfr para o tratamento de tumores | |
BR112018013733A2 (pt) | combinações anti-cd20 para o tratamento de tumores a | |
BR112016005816A2 (pt) | Combinação de anticorpos anti-lag-3 e anticorpos anti-pd-1 para tratar tumores | |
BR112016005303A2 (pt) | anticorpos anti-b7-h1 para tratamento de tumores | |
BR112018014016A2 (pt) | combinação de um agonista de ox40 e um agonista de anticorpo monoclonal 4-1bb para tratamento de câncer | |
MX2018008346A (es) | Terapia de combinación de virus oncológico e inhibidor de punto de control. | |
EA201790192A1 (ru) | СПОСОБ СНИЖЕНИЯ Fc-РЕЦЕПТОРНОГО СВЯЗЫВАНИЯ МОЛЕКУЛ СЫВОРОТОЧНОГО IgG У СУБЪЕКТА | |
EA201992251A1 (ru) | Противораковые вакцины и способы лечения с их применением | |
MX2022008868A (es) | Tratamiento del cancer con tg02. | |
BR112015030356A2 (pt) | métodos de tratamento de uma taupatia | |
MX2016014306A (es) | Marcadores para terapia con lipoproteinas de alta densidad (hdl). | |
CL2017002983A1 (es) | Terapia combinada de un anticuerpo anti-cd-20 con un inhibidor de bcl-2 y un inhibidor de mdm2 | |
EA201791736A1 (ru) | Комбинированная терапия для лечения рака | |
AR101740A1 (es) | Terapia de combinación y composiciones | |
BR112019001398A2 (pt) | métodos para tratamento de câncer de próstata | |
BR112017025533A2 (pt) | método para tratar câncer em um paciente humano | |
BR112017005235A2 (pt) | vetores virais adeno-associados para o tratamento de glaucoma de miocilina (myoc) | |
CO2022009696A2 (es) | Anticuerpo anti-lilrb1 y usos del mismo | |
BR112019008241A2 (pt) | tratamento do prurigo nodular | |
EA201791819A1 (ru) | Комбинированная терапия с применением конъюгата антитела против cd19 с лекарственным средством и винкристина |