BR112017025189A2 - composição e usos da mesma - Google Patents
composição e usos da mesmaInfo
- Publication number
- BR112017025189A2 BR112017025189A2 BR112017025189A BR112017025189A BR112017025189A2 BR 112017025189 A2 BR112017025189 A2 BR 112017025189A2 BR 112017025189 A BR112017025189 A BR 112017025189A BR 112017025189 A BR112017025189 A BR 112017025189A BR 112017025189 A2 BR112017025189 A2 BR 112017025189A2
- Authority
- BR
- Brazil
- Prior art keywords
- treating
- preventing
- methods
- diabetes
- variety
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 238000000034 method Methods 0.000 abstract 3
- 206010061218 Inflammation Diseases 0.000 abstract 2
- 239000008280 blood Substances 0.000 abstract 2
- 210000004369 blood Anatomy 0.000 abstract 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
- 230000004054 inflammatory process Effects 0.000 abstract 2
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 206010018429 Glucose tolerance impaired Diseases 0.000 abstract 1
- 108090000526 Papain Proteins 0.000 abstract 1
- 235000005105 Pinus pinaster Nutrition 0.000 abstract 1
- 241001236212 Pinus pinaster Species 0.000 abstract 1
- 208000001280 Prediabetic State Diseases 0.000 abstract 1
- 239000004365 Protease Substances 0.000 abstract 1
- 235000014104 aloe vera supplement Nutrition 0.000 abstract 1
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 229940055729 papain Drugs 0.000 abstract 1
- 235000019834 papain Nutrition 0.000 abstract 1
- 201000009104 prediabetes syndrome Diseases 0.000 abstract 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/15—Pinaceae (Pine family), e.g. pine or cedar
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4873—Cysteine endopeptidases (3.4.22), e.g. stem bromelain, papain, ficin, cathepsin H
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/22—Cysteine endopeptidases (3.4.22)
- C12Y304/22002—Papain (3.4.22.2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Emergency Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Child & Adolescent Psychology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
Abstract
a invenção refere-se a composições compreendendo extrato da casca do tronco de pinus pinaster, papaína e extrato de aloe vera e métodos para produzir as mesmas. também são descritos métodos de tratamento ou prevenção de uma variedade de condições, incluindo o tratamento ou a prevenção de glicemia elevada, pré-diabetes, diabetes tipo 2, doenças autoimunes, redução ou diminuição da inflamação, tratamento ou prevenção de doenças definidas por níveis elevados de inflamação e diminuição do colesterol no sangue, os referidos métodos compreendendo administrar uma quantidade eficaz de uma composição de acordo com a invenção a um indivíduo que dele necessite. são também descritos os usos da composição da invenção para a fabricação de um medicamento para tratar ou prevenir uma variedade de condições.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2015901913A AU2015901913A0 (en) | 2015-05-25 | Composition and uses thereof | |
AU2015901913 | 2015-05-25 | ||
PCT/AU2015/000406 WO2016187643A1 (en) | 2015-05-25 | 2015-07-14 | Composition and uses thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112017025189A2 true BR112017025189A2 (pt) | 2018-07-31 |
BR112017025189B1 BR112017025189B1 (pt) | 2021-05-04 |
Family
ID=57392254
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112017025189-2A BR112017025189B1 (pt) | 2015-05-25 | 2015-07-14 | composições compreendendo extrato da casca do tronco de pinus pinaster, seu método de fabricação e usos das mesmas |
Country Status (15)
Country | Link |
---|---|
US (2) | US20180153970A1 (pt) |
EP (1) | EP3302513A4 (pt) |
JP (2) | JP2018522828A (pt) |
KR (1) | KR20180043201A (pt) |
CN (1) | CN107735099A (pt) |
AU (1) | AU2015396019B2 (pt) |
BR (1) | BR112017025189B1 (pt) |
CA (1) | CA2987143A1 (pt) |
HK (1) | HK1250915A1 (pt) |
MX (1) | MX2017015129A (pt) |
MY (1) | MY197721A (pt) |
NZ (1) | NZ737567A (pt) |
PH (1) | PH12017502145A1 (pt) |
RU (1) | RU2695331C1 (pt) |
WO (1) | WO2016187643A1 (pt) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20220233487A1 (en) | 2019-05-06 | 2022-07-28 | Evonik Operations Gmbh | Preparation for use in weight management comprising omega-3 fatty acid salts and basic amino acids |
US20210196772A1 (en) * | 2019-12-27 | 2021-07-01 | Grove Collaborative, Inc. | Confections for skin protection: compositions, methods for making, and applications thereof |
IT202000017242A1 (it) * | 2020-07-16 | 2022-01-16 | Sinergy Pharma S R L | Composizione orale per il mantenimento dei livelli normali di zuccheri nel sangue |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR023208A1 (es) * | 1999-03-29 | 2002-09-04 | Nutrasweet Co | Nutraceuticos con 1-metil ester de n-[n-3,3-dimetilbutil)-l-alfa-aspartil]-l-fenilalanina |
JP4708744B2 (ja) | 2004-07-15 | 2011-06-22 | 株式会社シールド・ラボ | 血小板凝集抑制組成物 |
US7772195B2 (en) * | 2004-07-29 | 2010-08-10 | Board Of Trustees Of Michigan State University | Methods and compositions for the treatment of obesity, insulin related diseases and hypercholesterolemia |
JP2006160679A (ja) * | 2004-12-08 | 2006-06-22 | Mitsukan Group Honsha:Kk | Ii型糖尿病改善用組成物 |
WO2008079898A1 (en) * | 2006-12-20 | 2008-07-03 | Pharmwest, Inc. | Methods and topical formulations comprising colloidal metal for treating or preventing skin conditions |
JP2009126814A (ja) * | 2007-11-22 | 2009-06-11 | Tsujido Kagaku Kk | 高尿酸血症の予防または改善剤 |
MX2010007828A (es) | 2008-01-18 | 2010-12-17 | Indena Spa | Tratamiento de presion intraocular anormal. |
ES2316312B1 (es) | 2008-06-20 | 2010-02-08 | Ignacio Umbert Millet | Composicion farmaceutica dermatologica para el tratamiento de patologias de inflamacion de la piel, tales como por ejemplo dermatitis, dermatitis atopica, vitiligo, alopecia areata, acne, psoriasis y prurito,y combinaciones de las mismas. |
CN102847159A (zh) * | 2011-06-29 | 2013-01-02 | 智乐斯科学有限公司 | 一种葡萄糖新陈代谢增强剂 |
JP6148676B2 (ja) * | 2011-11-04 | 2017-06-14 | リポテック, エセ.ア. | 活性化受容体を阻害するペプチド、および化粧品組成物または薬学的組成物におけるそれらの使用 |
CN103550121A (zh) * | 2013-10-30 | 2014-02-05 | 青岛叁鼎卫生制品有限公司 | 一种护肤驱蚊湿巾 |
CN104224683B (zh) * | 2014-09-16 | 2016-09-07 | 上海芊墨化妆品有限公司 | 改善黄种人肌肤新陈代谢延缓衰老的天然植物护肤品 |
-
2015
- 2015-07-14 EP EP15892804.4A patent/EP3302513A4/en active Pending
- 2015-07-14 CA CA2987143A patent/CA2987143A1/en active Pending
- 2015-07-14 AU AU2015396019A patent/AU2015396019B2/en active Active
- 2015-07-14 US US15/576,416 patent/US20180153970A1/en not_active Abandoned
- 2015-07-14 RU RU2017140796A patent/RU2695331C1/ru active
- 2015-07-14 WO PCT/AU2015/000406 patent/WO2016187643A1/en active Application Filing
- 2015-07-14 JP JP2017561751A patent/JP2018522828A/ja active Pending
- 2015-07-14 MX MX2017015129A patent/MX2017015129A/es unknown
- 2015-07-14 MY MYPI2017001724A patent/MY197721A/en unknown
- 2015-07-14 CN CN201580081128.8A patent/CN107735099A/zh active Pending
- 2015-07-14 NZ NZ737567A patent/NZ737567A/en unknown
- 2015-07-14 BR BR112017025189-2A patent/BR112017025189B1/pt active IP Right Grant
- 2015-07-14 KR KR1020177034150A patent/KR20180043201A/ko not_active Application Discontinuation
-
2017
- 2017-11-24 PH PH12017502145A patent/PH12017502145A1/en unknown
-
2018
- 2018-08-10 HK HK18110283.5A patent/HK1250915A1/zh unknown
-
2019
- 2019-10-04 US US16/592,965 patent/US20200113982A1/en not_active Abandoned
-
2020
- 2020-12-25 JP JP2020217419A patent/JP7278253B2/ja active Active
Also Published As
Publication number | Publication date |
---|---|
HK1250915A1 (zh) | 2019-01-18 |
EP3302513A4 (en) | 2019-01-23 |
AU2015396019A1 (en) | 2017-03-09 |
PH12017502145A1 (en) | 2018-05-28 |
CA2987143A1 (en) | 2016-12-01 |
WO2016187643A1 (en) | 2016-12-01 |
JP2018522828A (ja) | 2018-08-16 |
US20200113982A1 (en) | 2020-04-16 |
AU2015396019B2 (en) | 2017-10-12 |
NZ737567A (en) | 2022-10-28 |
KR20180043201A (ko) | 2018-04-27 |
EP3302513A1 (en) | 2018-04-11 |
JP2021059589A (ja) | 2021-04-15 |
CN107735099A (zh) | 2018-02-23 |
US20180153970A1 (en) | 2018-06-07 |
MX2017015129A (es) | 2018-07-06 |
RU2695331C1 (ru) | 2019-07-23 |
MY197721A (en) | 2023-07-10 |
JP7278253B2 (ja) | 2023-05-19 |
BR112017025189B1 (pt) | 2021-05-04 |
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