BR112017019260A2 - métodos, sistemas e aparelhos para classificação e processamento de analitos - Google Patents

métodos, sistemas e aparelhos para classificação e processamento de analitos

Info

Publication number
BR112017019260A2
BR112017019260A2 BR112017019260A BR112017019260A BR112017019260A2 BR 112017019260 A2 BR112017019260 A2 BR 112017019260A2 BR 112017019260 A BR112017019260 A BR 112017019260A BR 112017019260 A BR112017019260 A BR 112017019260A BR 112017019260 A2 BR112017019260 A2 BR 112017019260A2
Authority
BR
Brazil
Prior art keywords
analyte
radiation source
systems
beams
processing methods
Prior art date
Application number
BR112017019260A
Other languages
English (en)
Inventor
M Anchieta Crispulo
Humphreys Daniel
qi Daniel
G Rodgers Edward
LAO Edward
Chiou Jeff
patrick myers John
Carter Joseph
Luscher Mark
De Martini Michael
Marks Randall
Original Assignee
Microbix Biosystems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbix Biosystems Inc filed Critical Microbix Biosystems Inc
Publication of BR112017019260A2 publication Critical patent/BR112017019260A2/pt

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434Optical arrangements
    • G01N15/1436Optical arrangements the optical arrangement forming an integrated apparatus with the sample container, e.g. a flow cell
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1425Optical investigation techniques, e.g. flow cytometry using an analyser being characterised by its control arrangement
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404Handling flow, e.g. hydrodynamic focusing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434Optical arrangements
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/149Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N2015/1006Investigating individual particles for cytology
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404Handling flow, e.g. hydrodynamic focusing
    • G01N2015/1413Hydrodynamic focussing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434Optical arrangements
    • G01N2015/1452Adjustment of focus; Alignment

Landscapes

  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

um método de configuração de um sistema óptico para reduzir as variações nas propriedades medidas de um analito inclui selecionar um número de feixes nos quais a radiação de uma fonte de radiação deve ser dividida, em que, ao irradiar o analito a partir de uma pluralidade de direções pelo número de feixes, uma variação de uma medida resultante do analito está em ou abaixo de um limite. o método inclui adicionalmente o alinhamento da fonte de radiação e uma pluralidade de elementos ópticos acoplados opticamente à fonte de radiação, de modo que o número de feixes selecionado irradie o analito após emissão de radiação pela fonte de radiação.
BR112017019260A 2015-03-10 2016-03-10 métodos, sistemas e aparelhos para classificação e processamento de analitos BR112017019260A2 (pt)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US201562131022P 2015-03-10 2015-03-10
US201562130825P 2015-03-10 2015-03-10
US201562130957P 2015-03-10 2015-03-10
US201562130821P 2015-03-10 2015-03-10
US201562131036P 2015-03-10 2015-03-10
US201562131043P 2015-03-10 2015-03-10
US201562140336P 2015-03-30 2015-03-30
US201562140199P 2015-03-30 2015-03-30
US201562140173P 2015-03-30 2015-03-30
PCT/IB2016/000405 WO2016142785A1 (en) 2015-03-10 2016-03-10 Methods, systems and apparatus for sorting and processing analytes

Publications (1)

Publication Number Publication Date
BR112017019260A2 true BR112017019260A2 (pt) 2018-05-02

Family

ID=56880224

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017019260A BR112017019260A2 (pt) 2015-03-10 2016-03-10 métodos, sistemas e aparelhos para classificação e processamento de analitos

Country Status (8)

Country Link
US (1) US10866182B2 (pt)
EP (1) EP3268720A4 (pt)
CN (1) CN107532991A (pt)
AU (1) AU2016230830A1 (pt)
BR (1) BR112017019260A2 (pt)
CA (1) CA2979039A1 (pt)
MX (1) MX2017011601A (pt)
WO (1) WO2016142785A1 (pt)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3472591B1 (en) * 2016-06-20 2023-08-30 Plair SA Device and method for detecting and/or characterizing fluid-borne particles
US10525731B2 (en) * 2016-09-08 2020-01-07 Xerox Coporation Image aware laser diode array shutter for reduced incident energy on DMD chip set
KR101835815B1 (ko) * 2016-12-16 2018-03-07 (주) 인텍플러스 형광수명 측정장치 및 측정방법
US10788413B2 (en) * 2017-01-05 2020-09-29 Massachusetts Institute Of Technology Method to distinguish and analyze white blood cells in the presence of red blood cells
US10069027B1 (en) 2017-09-15 2018-09-04 Premium Genetics (Uk) Ltd Cytometer sperm sex sensing apparatus with an avalanche photodiode
KR102491854B1 (ko) 2017-09-29 2023-01-26 삼성전자주식회사 분광기
CN108120665A (zh) * 2017-12-28 2018-06-05 无锡奥芬光电科技有限公司 单色结构光检查微小颗粒的方法及设备
BR112020013841A2 (pt) * 2018-01-23 2020-12-01 Becton, Dickinson And Company sistemas para obscuração dinâmica de detecção de luz e métodos para uso dos mesmos
US11022538B2 (en) * 2018-05-15 2021-06-01 Government Of The United States Of America, As Represented By The Secretary Of Commerce Quantum flow cytometer
US10746596B2 (en) * 2018-06-18 2020-08-18 Harry Owen Probe optic light shields
JP7058565B2 (ja) * 2018-06-26 2022-04-22 三菱化工機株式会社 固形成分分離装置の制御装置、固形成分分離装置、舶用排気ガススクラバーシステム、および舶用ディーゼルエンジン
EP3830545A1 (en) * 2018-08-03 2021-06-09 Verily Life Sciences LLC Systems and methods for detecting particles in a fluid channel
CN108760641B (zh) * 2018-08-17 2023-05-16 龙岩学院 基于单光子探测的熔焊过程监测装置及监测方法
WO2020047468A1 (en) * 2018-08-30 2020-03-05 Becton, Dickinson And Company Characterization and sorting for particle analyzers
US10908065B2 (en) * 2018-09-17 2021-02-02 Inguran, Llc Light collection from objects within a fluid column
KR101970690B1 (ko) * 2018-09-28 2019-08-13 피엠씨씨 주식회사 다중 형광 신호 측정을 위한 광수신장치
US11288815B2 (en) * 2019-01-04 2022-03-29 Georgia Tech Research Corporation Systems and methods for tracking single-cell movement trajectories
JP7439438B2 (ja) * 2019-09-30 2024-02-28 ソニーグループ株式会社 生体粒子分析用マイクロチップ、生体粒子分析装置、微小粒子分析用マイクロチップ、及び微小粒子分析装置
EP4100717A1 (en) * 2020-02-03 2022-12-14 Lase Innovation Inc. Apparatus and method for cyclic flow cytometry using particularized cell identification
CN111235023A (zh) * 2020-03-25 2020-06-05 梨薯(厦门)科技有限公司 基于多通道触发的单颗粒检测方法
US11846578B2 (en) * 2020-09-28 2023-12-19 Lighthouse Worldwide Solutions Apparatus and method for characterization of particles
CN112240801A (zh) * 2020-10-13 2021-01-19 中国科学院长春光学精密机械与物理研究所 偏振成像系统
WO2022103574A1 (en) * 2020-11-16 2022-05-19 Becton, Dickinson And Company Flow cyometers including light collection modules, and methods of using the same
US20220268688A1 (en) * 2021-02-05 2022-08-25 Cytek Biosciences, Inc. Integrated compact cell sorter
CN117222881A (zh) * 2021-04-27 2023-12-12 生命科技股份有限公司 光纤节距调节
CN115808376B (zh) * 2022-12-12 2024-05-07 滨州学院 一种激光熔覆粉末流聚集性测量方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5252493A (en) 1986-09-22 1993-10-12 Nippon Telegraph And Telephone Corporation Laser magnetic immunoassay method and apparatus therefor
US5103106A (en) * 1990-09-11 1992-04-07 Moshe Golberstein Reflective optical instrument for measuring surface reflectance
US5329461A (en) * 1992-07-23 1994-07-12 Acrogen, Inc. Digital analyte detection system
JP3011836B2 (ja) * 1993-08-21 2000-02-21 日本カノマックス株式会社 粒子測定装置
IL121279A (en) * 1996-07-16 2001-05-20 Roche Diagnostics Gmbh An analytical system with means for testing samples with too small volumes
EP2306174B1 (en) * 2003-03-28 2016-05-11 Inguran, LLC Flow cytometry nozzle for orienting particles and corresponding method
EP1835323B1 (en) * 2004-12-08 2012-08-01 Osaka University Fluorescence microscope and observation method
DK2304020T3 (en) * 2008-06-30 2019-02-04 Microbix Biosystems Inc Method and apparatus for sorting cells
US7961306B2 (en) * 2009-03-30 2011-06-14 Tokyo Electron Limited Optimizing sensitivity of optical metrology measurements
JP5420437B2 (ja) * 2010-01-19 2014-02-19 株式会社オプティコン 粉末検出装置
EP2625507B1 (de) * 2010-10-08 2020-01-22 Mettler-Toledo GmbH Verfahren zum betreiben eines optochemischen sensors
EP2676121A1 (en) * 2011-02-15 2013-12-25 Microbix Biosystems Inc. Methods, systems, and apparatus for performing flow cytometry
CN102920464B (zh) * 2012-11-23 2014-12-24 扬州奥泰光电生物技术有限公司 血红蛋白浓度和血氧饱和度测定仪及测定方法
US9970929B2 (en) 2013-01-18 2018-05-15 Ark Diagnostics, Inc. Voriconazole immunoassays

Also Published As

Publication number Publication date
US10866182B2 (en) 2020-12-15
CA2979039A1 (en) 2016-09-15
MX2017011601A (es) 2017-11-17
AU2016230830A1 (en) 2017-11-02
EP3268720A4 (en) 2018-11-21
CN107532991A (zh) 2018-01-02
WO2016142785A1 (en) 2016-09-15
EP3268720A1 (en) 2018-01-17
US20180038784A1 (en) 2018-02-08

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]