BR112017016396A2 - composto, composição farmacêutica, uso de um composto, e, método. - Google Patents
composto, composição farmacêutica, uso de um composto, e, método.Info
- Publication number
- BR112017016396A2 BR112017016396A2 BR112017016396A BR112017016396A BR112017016396A2 BR 112017016396 A2 BR112017016396 A2 BR 112017016396A2 BR 112017016396 A BR112017016396 A BR 112017016396A BR 112017016396 A BR112017016396 A BR 112017016396A BR 112017016396 A2 BR112017016396 A2 BR 112017016396A2
- Authority
- BR
- Brazil
- Prior art keywords
- compound
- pharmaceutical composition
- disorder
- useful
- formula
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
- C07D513/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
trata-se de um composto de fórmula (i) ou um sal farmaceuticamente aceitável do mesmo. o composto é útil para uso no tratamento contra o câncer, um distúrbio inflamatório, um distúrbio autoimune ou um distúrbio neurodegenerativo.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP15153627 | 2015-02-03 | ||
PCT/EP2015/078683 WO2016042172A1 (en) | 2015-02-03 | 2015-12-04 | Imidazo[2,1-b]thiazole and 5,6-dihydroimidazo[2,1-b]thiazole derivatives useful as s100-inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112017016396A2 true BR112017016396A2 (pt) | 2018-03-27 |
Family
ID=52446251
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112017016396A BR112017016396A2 (pt) | 2015-02-03 | 2015-12-04 | composto, composição farmacêutica, uso de um composto, e, método. |
Country Status (11)
Country | Link |
---|---|
US (1) | US10385069B2 (pt) |
EP (1) | EP3253768A1 (pt) |
JP (1) | JP2018503692A (pt) |
KR (1) | KR20170113627A (pt) |
CN (1) | CN107466296A (pt) |
AU (1) | AU2015316719A1 (pt) |
BR (1) | BR112017016396A2 (pt) |
CA (1) | CA2973739A1 (pt) |
EA (1) | EA201791743A1 (pt) |
MX (1) | MX2017009597A (pt) |
WO (1) | WO2016042172A1 (pt) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101948805B1 (ko) | 2016-07-05 | 2019-02-15 | 한국과학기술연구원 | 항종양 효과를 갖는 이미다조옥사졸 유도체 및 이를 포함하는 약학적 조성물 |
US11332479B2 (en) | 2016-07-05 | 2022-05-17 | Korea Institute Of Science And Technology | Imidazooxazole derivative having antitumor effect, and pharmaceutical composition including same |
IL279972A (en) * | 2021-01-05 | 2022-08-01 | Anima Biotech Inc | Substances that function as modulators of cmyc-mrna translation and their uses in cancer treatment |
CN115448863B (zh) * | 2022-10-09 | 2024-03-26 | 浙江迪邦化工有限公司 | 一种3,4-二氯苯基硫脲的连续化制备工艺 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4137320A (en) | 1974-02-07 | 1979-01-30 | Plantex, Ltd. | Pharmaceutical compositions containing imidazo(2,1-b)thiazoles and process for reducing blood sugar levels therewith |
EP1387680A4 (en) * | 2001-03-05 | 2010-01-13 | Transtech Pharma Inc | AGENTS TH RAPEUTICES D RIV S BENZIMIDAZOLE BASE |
GB0416396D0 (en) | 2004-07-22 | 2004-08-25 | Angeletti P Ist Richerche Bio | Therapeutic agents |
US7605269B2 (en) | 2005-03-23 | 2009-10-20 | Actelion Pharmaceuticals Ltd. | Thiophene derivatives as Sphingosine-1-phosphate-1 receptor agonists |
-
2015
- 2015-12-04 WO PCT/EP2015/078683 patent/WO2016042172A1/en active Application Filing
- 2015-12-04 AU AU2015316719A patent/AU2015316719A1/en not_active Abandoned
- 2015-12-04 MX MX2017009597A patent/MX2017009597A/es unknown
- 2015-12-04 KR KR1020177024656A patent/KR20170113627A/ko unknown
- 2015-12-04 BR BR112017016396A patent/BR112017016396A2/pt not_active Application Discontinuation
- 2015-12-04 US US15/545,573 patent/US10385069B2/en active Active
- 2015-12-04 JP JP2017558617A patent/JP2018503692A/ja active Pending
- 2015-12-04 EA EA201791743A patent/EA201791743A1/ru unknown
- 2015-12-04 CA CA2973739A patent/CA2973739A1/en not_active Abandoned
- 2015-12-04 EP EP15804803.3A patent/EP3253768A1/en not_active Withdrawn
- 2015-12-04 CN CN201580078665.7A patent/CN107466296A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
AU2015316719A1 (en) | 2017-09-07 |
US10385069B2 (en) | 2019-08-20 |
JP2018503692A (ja) | 2018-02-08 |
MX2017009597A (es) | 2017-11-22 |
CA2973739A1 (en) | 2016-03-24 |
EA201791743A1 (ru) | 2017-12-29 |
KR20170113627A (ko) | 2017-10-12 |
WO2016042172A1 (en) | 2016-03-24 |
CN107466296A (zh) | 2017-12-12 |
US20180282348A1 (en) | 2018-10-04 |
EP3253768A1 (en) | 2017-12-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 5A ANUIDADE. |
|
B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |