BR112017014823A2 - composto antimicrobiano, composição farmacêutica, uso de composto antimicrobiano e método de tratamento de pacientes - Google Patents
composto antimicrobiano, composição farmacêutica, uso de composto antimicrobiano e método de tratamento de pacientesInfo
- Publication number
- BR112017014823A2 BR112017014823A2 BR112017014823A BR112017014823A BR112017014823A2 BR 112017014823 A2 BR112017014823 A2 BR 112017014823A2 BR 112017014823 A BR112017014823 A BR 112017014823A BR 112017014823 A BR112017014823 A BR 112017014823A BR 112017014823 A2 BR112017014823 A2 BR 112017014823A2
- Authority
- BR
- Brazil
- Prior art keywords
- antimicrobial compound
- pharmaceutical composition
- treating patients
- antimicrobial
- nisin
- Prior art date
Links
- 239000004599 antimicrobial Substances 0.000 title 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- NVNLLIYOARQCIX-MSHCCFNRSA-N Nisin Chemical compound N1C(=O)[C@@H](CC(C)C)NC(=O)C(=C)NC(=O)[C@@H]([C@H](C)CC)NC(=O)[C@@H](NC(=O)C(=C/C)/NC(=O)[C@H](N)[C@H](C)CC)CSC[C@@H]1C(=O)N[C@@H]1C(=O)N2CCC[C@@H]2C(=O)NCC(=O)N[C@@H](C(=O)N[C@H](CCCCN)C(=O)N[C@@H]2C(NCC(=O)N[C@H](C)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCSC)C(=O)NCC(=O)N[C@H](CS[C@@H]2C)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H](CCSC)C(=O)N[C@H](CCCCN)C(=O)N[C@@H]2C(N[C@H](C)C(=O)N[C@@H]3C(=O)N[C@@H](C(N[C@H](CC=4NC=NC=4)C(=O)N[C@H](CS[C@@H]3C)C(=O)N[C@H](CO)C(=O)N[C@H]([C@H](C)CC)C(=O)N[C@H](CC=3NC=NC=3)C(=O)N[C@H](C(C)C)C(=O)NC(=C)C(=O)N[C@H](CCCCN)C(O)=O)=O)CS[C@@H]2C)=O)=O)CS[C@@H]1C NVNLLIYOARQCIX-MSHCCFNRSA-N 0.000 abstract 5
- 108010053775 Nisin Proteins 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000004309 nisin Substances 0.000 abstract 3
- 235000010297 nisin Nutrition 0.000 abstract 3
- 230000000845 anti-microbial effect Effects 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Abstract
a presente invenção refere-se a novos compostos antimicrobianos derivados de nisina. particularmente, os compostos são baseados na estrutura de nisina [1-12] não substituída, em que os mencionados compostos possuem atividade antimicrobiana que excede a atividade da estrutura de nisina [1-12] não substituída.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL2014152 | 2015-01-19 | ||
| NL2014670 | 2015-04-20 | ||
| PCT/EP2016/050827 WO2016116379A1 (en) | 2015-01-19 | 2016-01-15 | Nisin-based compounds and use thereof in the treatment of bacterial infections |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112017014823A2 true BR112017014823A2 (pt) | 2018-01-09 |
Family
ID=55273206
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112017014823A BR112017014823A2 (pt) | 2015-01-19 | 2016-01-15 | composto antimicrobiano, composição farmacêutica, uso de composto antimicrobiano e método de tratamento de pacientes |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20170362283A1 (pt) |
| EP (1) | EP3247379A1 (pt) |
| JP (1) | JP2018505871A (pt) |
| KR (1) | KR20170102356A (pt) |
| CN (1) | CN107108702A (pt) |
| AU (1) | AU2016208702A1 (pt) |
| BR (1) | BR112017014823A2 (pt) |
| CA (1) | CA2972836A1 (pt) |
| IL (1) | IL253418A0 (pt) |
| MX (1) | MX2017009213A (pt) |
| SG (1) | SG11201705397WA (pt) |
| WO (1) | WO2016116379A1 (pt) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109627301B (zh) * | 2019-02-18 | 2022-08-05 | 浙江新银象生物工程有限公司 | Nisin固体稳定剂开发及应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1996217B1 (en) * | 2006-03-09 | 2010-11-10 | Cambridge Enterprise Limited | Novel antibiotic compositions |
| AR073014A1 (es) * | 2008-08-12 | 2010-10-06 | Dsm Ip Assets Bv | Composiciones liquidas de nisina |
| RU2506272C2 (ru) * | 2008-11-24 | 2014-02-10 | Сентинелла Фармасьютикалз, Инк. ("Сентинелла") | Лантибиотические карбоксиамидные производные с усиленной антибактериальной активностью |
| EP2925342A4 (en) * | 2012-11-30 | 2016-07-06 | Naicons Srl | NOVEL LANTIBIOTIC DERIVATIVES AND PREPARATION METHOD THEREOF |
-
2016
- 2016-01-15 KR KR1020177022438A patent/KR20170102356A/ko unknown
- 2016-01-15 JP JP2017537955A patent/JP2018505871A/ja active Pending
- 2016-01-15 BR BR112017014823A patent/BR112017014823A2/pt not_active Application Discontinuation
- 2016-01-15 CN CN201680006212.8A patent/CN107108702A/zh active Pending
- 2016-01-15 MX MX2017009213A patent/MX2017009213A/es unknown
- 2016-01-15 EP EP16702338.1A patent/EP3247379A1/en not_active Withdrawn
- 2016-01-15 AU AU2016208702A patent/AU2016208702A1/en not_active Abandoned
- 2016-01-15 US US15/543,660 patent/US20170362283A1/en not_active Abandoned
- 2016-01-15 SG SG11201705397WA patent/SG11201705397WA/en unknown
- 2016-01-15 CA CA2972836A patent/CA2972836A1/en not_active Abandoned
- 2016-01-15 WO PCT/EP2016/050827 patent/WO2016116379A1/en active Application Filing
-
2017
- 2017-07-11 IL IL253418A patent/IL253418A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2016208702A1 (en) | 2017-07-20 |
| JP2018505871A (ja) | 2018-03-01 |
| WO2016116379A1 (en) | 2016-07-28 |
| EP3247379A1 (en) | 2017-11-29 |
| MX2017009213A (es) | 2017-11-01 |
| KR20170102356A (ko) | 2017-09-08 |
| SG11201705397WA (en) | 2017-08-30 |
| IL253418A0 (en) | 2017-09-28 |
| CN107108702A (zh) | 2017-08-29 |
| CA2972836A1 (en) | 2016-07-28 |
| US20170362283A1 (en) | 2017-12-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |