BR112017014162A2 - imidazo[1,2-a] quinoxalinas e derivados do mesmo para o tratamento dos cânceres - Google Patents

imidazo[1,2-a] quinoxalinas e derivados do mesmo para o tratamento dos cânceres

Info

Publication number
BR112017014162A2
BR112017014162A2 BR112017014162-0A BR112017014162A BR112017014162A2 BR 112017014162 A2 BR112017014162 A2 BR 112017014162A2 BR 112017014162 A BR112017014162 A BR 112017014162A BR 112017014162 A2 BR112017014162 A2 BR 112017014162A2
Authority
BR
Brazil
Prior art keywords
imidazo
quinoxalines
derivatives
cancer treatment
compounds
Prior art date
Application number
BR112017014162-0A
Other languages
English (en)
Inventor
Cuq Pierre
Deleuze-Masquefa Carine
Antoine Bonnet Pierre-
Patinote Cindy
Original Assignee
Universite De Montpellier
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universite De Montpellier filed Critical Universite De Montpellier
Publication of BR112017014162A2 publication Critical patent/BR112017014162A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

(i) a presente invenção refere-se a compostos imidazo[1,2-a] quinoxalina de fórmula (1) para o tratamento dos cânceres, assim como às composições farmacêuticas, compreendendo esses referidos compostos e as utilizações em terapia dos mesmos.
BR112017014162-0A 2014-12-31 2015-12-30 imidazo[1,2-a] quinoxalinas e derivados do mesmo para o tratamento dos cânceres BR112017014162A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR1463480 2014-12-31
FR1463480A FR3031105B1 (fr) 2014-12-31 2014-12-31 Nouveaux imidazo[1,2-a]quinoxalines et derives pour le traitement des cancers
PCT/EP2015/081397 WO2016107895A1 (fr) 2014-12-31 2015-12-30 Nouveaux imidazo[1,2-a]quinoxalines et dérivés pour le traitement des cancers

Publications (1)

Publication Number Publication Date
BR112017014162A2 true BR112017014162A2 (pt) 2018-01-02

Family

ID=52692888

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017014162-0A BR112017014162A2 (pt) 2014-12-31 2015-12-30 imidazo[1,2-a] quinoxalinas e derivados do mesmo para o tratamento dos cânceres

Country Status (11)

Country Link
US (1) US10689384B2 (pt)
EP (1) EP3240789B1 (pt)
JP (1) JP6703006B2 (pt)
CN (1) CN107454900B (pt)
AU (1) AU2015373422B2 (pt)
BR (1) BR112017014162A2 (pt)
CA (1) CA2972511A1 (pt)
FR (1) FR3031105B1 (pt)
MX (1) MX2017008808A (pt)
WO (1) WO2016107895A1 (pt)
ZA (1) ZA201704727B (pt)

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL73534A (en) 1983-11-18 1990-12-23 Riker Laboratories Inc 1h-imidazo(4,5-c)quinoline-4-amines,their preparation and pharmaceutical compositions containing certain such compounds
US5182386A (en) 1991-08-27 1993-01-26 Neurogen Corporation Certain imidazoquinoxalinones; a new class of gaba brain receptor ligands
JPH10513435A (ja) * 1994-09-30 1998-12-22 ビーエーエスエフ アクチェンゲゼルシャフト 複素環で置換された新規イミダゾロキノキサリノン、その製造および使用
US6869956B2 (en) 2000-10-03 2005-03-22 Bristol-Myers Squibb Company Methods of treating inflammatory and immune diseases using inhibitors of IκB kinase (IKK)
US20060025419A1 (en) 2004-06-25 2006-02-02 Ann Richmond Imidazoquinoxaline compound for the treatment of melanoma
EP1831214A1 (en) 2004-12-27 2007-09-12 Usv Limited A process for preparation of 4-amino-1-isobutyl-1h-imidazo[4,5-c]-quinoline (imiquimod)
MX2008009475A (es) 2006-01-23 2008-10-20 Amira Pharmaceuticals Inc Inhibidores triciclicos de 5-lipoxigenasa.
ATE539079T1 (de) 2006-03-23 2012-01-15 Novartis Ag Imidazochinoxalinverbindungen als immunmodulatoren
EP1972629A1 (en) * 2007-03-23 2008-09-24 Mutabilis SA New imidazolo-heteroaryl derivatives with antibacterial properties
FR2921927B1 (fr) * 2007-10-03 2012-10-12 Univ De Montpellier 1 Imidazo°1,2-a!quinoxalines et derives pour le traitement des cancers
CN102413831B (zh) * 2009-04-29 2014-06-04 拜耳知识产权有限责任公司 取代的咪唑并喹喔啉

Also Published As

Publication number Publication date
US20180016278A1 (en) 2018-01-18
EP3240789B1 (fr) 2020-07-29
FR3031105B1 (fr) 2018-04-06
MX2017008808A (es) 2018-03-15
FR3031105A1 (fr) 2016-07-01
WO2016107895A1 (fr) 2016-07-07
CN107454900A (zh) 2017-12-08
CA2972511A1 (fr) 2016-07-07
AU2015373422A8 (en) 2017-08-24
JP6703006B2 (ja) 2020-06-03
EP3240789A1 (fr) 2017-11-08
AU2015373422B2 (en) 2020-07-09
AU2015373422A1 (en) 2017-08-17
ZA201704727B (en) 2021-05-26
JP2018502914A (ja) 2018-02-01
CN107454900B (zh) 2020-08-07
US10689384B2 (en) 2020-06-23

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements