BR112017012021A2 - um processo para a fabricação de idalopirdina - Google Patents

um processo para a fabricação de idalopirdina

Info

Publication number
BR112017012021A2
BR112017012021A2 BR112017012021A BR112017012021A BR112017012021A2 BR 112017012021 A2 BR112017012021 A2 BR 112017012021A2 BR 112017012021 A BR112017012021 A BR 112017012021A BR 112017012021 A BR112017012021 A BR 112017012021A BR 112017012021 A2 BR112017012021 A2 BR 112017012021A2
Authority
BR
Brazil
Prior art keywords
idalopirdine
manufacture
preparation
disclosed
pharmaceutically acceptable
Prior art date
Application number
BR112017012021A
Other languages
English (en)
Inventor
Fog Jacobsen Mikkel
Nielsen Ole
Original Assignee
H Lundbeck As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H Lundbeck As filed Critical H Lundbeck As
Priority claimed from PCT/EP2015/079209 external-priority patent/WO2016091997A1/en
Publication of BR112017012021A2 publication Critical patent/BR112017012021A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

é revelado no presente documento um processo para a preparação de idalopirdina e sais farmaceuticamente aceitáveis da mesma.
BR112017012021A 2014-12-12 2015-12-10 um processo para a fabricação de idalopirdina BR112017012021A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA201400721 2014-12-12
PCT/EP2015/079209 WO2016091997A1 (en) 2014-12-12 2015-12-10 A process for the manufacture of idalopirdine

Publications (1)

Publication Number Publication Date
BR112017012021A2 true BR112017012021A2 (pt) 2018-03-13

Family

ID=59011415

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017012021A BR112017012021A2 (pt) 2014-12-12 2015-12-10 um processo para a fabricação de idalopirdina

Country Status (13)

Country Link
EP (1) EP3230265A1 (pt)
JP (1) JP2017537128A (pt)
KR (1) KR20170093821A (pt)
CN (1) CN107001266A (pt)
AU (1) AU2015359347A1 (pt)
BR (1) BR112017012021A2 (pt)
CA (1) CA2968770A1 (pt)
CL (1) CL2017001466A1 (pt)
CO (1) CO2017005357A2 (pt)
IL (1) IL252471A0 (pt)
MA (1) MA41148A (pt)
MX (1) MX2017007510A (pt)
RU (1) RU2017120216A (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI3231793T1 (sl) 2014-12-12 2020-07-31 Japan Tobacco Inc. Spojine dihidropirimidin-2-ona in njihove medicinske uporabe

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3042685A (en) * 1962-07-03 Process of making g-fluoro tryptamine
AR065804A1 (es) * 2007-03-23 2009-07-01 Smithkline Beecham Corp Compuesto de indol carboxamida, composicion farmaceutica que lo comprende y uso de dicho compuesto para preparar un medicamento
TW201139370A (en) * 2009-12-23 2011-11-16 Lundbeck & Co As H Processes for the manufacture of a pharmaceutically active agent

Also Published As

Publication number Publication date
EP3230265A1 (en) 2017-10-18
AU2015359347A1 (en) 2017-06-08
MX2017007510A (es) 2017-08-22
MA41148A (fr) 2017-10-17
CN107001266A (zh) 2017-08-01
KR20170093821A (ko) 2017-08-16
CO2017005357A2 (es) 2017-09-20
JP2017537128A (ja) 2017-12-14
CL2017001466A1 (es) 2018-01-05
IL252471A0 (en) 2017-07-31
CA2968770A1 (en) 2016-06-16
RU2017120216A (ru) 2019-01-15

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]