BR112017008117A2 - suporte de biomaterial para regenerar a mucosa oral - Google Patents

suporte de biomaterial para regenerar a mucosa oral

Info

Publication number
BR112017008117A2
BR112017008117A2 BR112017008117A BR112017008117A BR112017008117A2 BR 112017008117 A2 BR112017008117 A2 BR 112017008117A2 BR 112017008117 A BR112017008117 A BR 112017008117A BR 112017008117 A BR112017008117 A BR 112017008117A BR 112017008117 A2 BR112017008117 A2 BR 112017008117A2
Authority
BR
Brazil
Prior art keywords
hydrogel
biomaterial support
oral mucosa
regenerate
biomaterial
Prior art date
Application number
BR112017008117A
Other languages
English (en)
Other versions
BR112017008117B1 (pt
Inventor
Baiget Orts Amparo
Castro Feo Begoña
Original Assignee
Histocell Sl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Histocell Sl filed Critical Histocell Sl
Publication of BR112017008117A2 publication Critical patent/BR112017008117A2/pt
Publication of BR112017008117B1 publication Critical patent/BR112017008117B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/225—Fibrin; Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/26—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3616—Blood, e.g. platelet-rich plasma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/34—Materials or treatment for tissue regeneration for soft tissue reconstruction

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Botany (AREA)
  • Cell Biology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Polymers & Plastics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

a presente invenção refere-se a um processo para a preparação de um suporte de biomaterial, sendo que o dito método compreende, (a) fornecer um hidrogel que compreende uma rede de fibrina e uma rede de polissacarídeo; (b) submeter o hidrogel da etapa a) a um processo de congelamento e descongelamento para reticular fisicamente o hidrogel; e (c) submeter o hidrogel fisicamente reticulado obtido após conduzir a etapa b), a uma liofilização. a invenção também se refere ao suporte de biomaterial obtenível pelo processo conforme definido anteriormente, bem como o dito suporte de biomaterial para seu uso de modo a aumentar, restaurar ou substituir parcial ou completamente a atividade funcional de uma mucosa oral doente ou danificada.
BR112017008117-2A 2014-10-24 2015-10-23 suporte de biomaterial para regenerar a mucosa oral BR112017008117B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14382417.5A EP3011981A1 (en) 2014-10-24 2014-10-24 A biomaterial scaffold for regenerating the oral mucosa
EP14382417.5 2014-10-24
PCT/EP2015/074610 WO2016062862A1 (en) 2014-10-24 2015-10-23 A biomaterial scaffold for regenerating the oral mucosa

Publications (2)

Publication Number Publication Date
BR112017008117A2 true BR112017008117A2 (pt) 2018-02-20
BR112017008117B1 BR112017008117B1 (pt) 2020-12-08

Family

ID=51844651

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017008117-2A BR112017008117B1 (pt) 2014-10-24 2015-10-23 suporte de biomaterial para regenerar a mucosa oral

Country Status (11)

Country Link
US (1) US11241516B2 (pt)
EP (2) EP3011981A1 (pt)
JP (1) JP6633628B2 (pt)
KR (1) KR102489773B1 (pt)
CN (1) CN107073170B (pt)
AU (1) AU2015334897B2 (pt)
BR (1) BR112017008117B1 (pt)
CA (1) CA2964501C (pt)
ES (1) ES2774792T3 (pt)
MX (1) MX2017005373A (pt)
WO (1) WO2016062862A1 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018106414A1 (en) * 2016-12-07 2018-06-14 Mayo Foundation For Medical Education And Research Methods and materials for using fibrin supports for retinal pigment epithelium transplantation
WO2019152766A1 (en) 2018-02-01 2019-08-08 North Carolina State University Antimicrobial platelet-like particles
CN110760076B (zh) * 2019-11-06 2022-04-08 大连理工大学 一种基于胶体颗粒-iPRF双网络结构的可注射、高强度复合水凝胶及其制备方法和应用
CN110743038B (zh) * 2019-11-06 2021-09-10 大连理工大学 一种双网络结构复合水凝胶及其制备方法和应用
US20230015266A1 (en) * 2019-11-29 2023-01-19 North Carolina State University Neonatal fibrin scaffolds for promoting wound healing
CN110982125B (zh) * 2019-12-19 2022-01-21 武汉纺织大学 一种形状自恢复多孔复合凝胶及其制备方法与应用
CN113318275B (zh) * 2021-08-03 2021-11-02 首都医科大学附属北京口腔医院 用于牙髓牙本质再生的可降解水凝胶
CN113862332A (zh) * 2021-09-17 2021-12-31 浙江大学 琼脂糖在制备生物大分子冻干保护剂中的应用
CN114146223A (zh) * 2021-12-10 2022-03-08 三亚悦美科技有限公司 一种重组胶原蛋白复合注射剂及其制备方法
EP4241798A1 (en) * 2022-03-11 2023-09-13 Universidad de Granada Hydrogel suitable to produce artificial tissues

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4438198A (en) * 1981-09-30 1984-03-20 Trimedyne, Inc. Biochemically active matrix for use in a bio-artificial organ
EP0615452A4 (en) 1991-11-25 1995-07-12 Inst Molecular Biology Inc MEDICINE SERVING THE PROMOTION OF THE GROWTH OF A NERVE IN MAMMALS.
WO2000006724A1 (fr) 1998-07-31 2000-02-10 Kirin Beer Kabushiki Kaisha Medicaments permettant de soigner la neuropathie contenant de la galectine-1 ou ses derives comme substance active
IL144446A0 (en) * 2001-07-19 2002-05-23 Prochon Biotech Ltd Plasma protein matrices and methods for their preparation
US8080418B2 (en) * 2007-03-09 2011-12-20 Corning Incorporated Method of making a three dimensional cell culture matrix
ES2677945T3 (es) 2009-08-25 2018-08-07 Servicio Andaluz De Salud Producción de tejidos artificiales mediante ingeniería tisular utilizando biomateriales de fibrina y agarosa
KR20110023399A (ko) * 2009-08-31 2011-03-08 한국과학기술연구원 지혈효과 및 기계적 물성이 우수한 지능형 피브린 생체접착제
WO2011151832A1 (en) 2010-06-03 2011-12-08 Ramot At Tel-Aviv University Ltd. Malleable hydrogel hybrids made of self-assembled peptides and biocompatible polymers and uses thereof
EP2594295A1 (en) * 2011-11-16 2013-05-22 Servicio Andaluz De Salud Nerve implants based on a compacted biomaterial containing cells
CN102688525B (zh) * 2012-05-07 2013-11-27 东南大学 一种生物大分子水凝胶及其制备方法
CN103908693B (zh) * 2014-04-15 2015-10-28 山东颐诺生物科技有限公司 一种仿生型海藻酸基复合抗菌敷料及其制备方法

Also Published As

Publication number Publication date
US20170340771A1 (en) 2017-11-30
JP2017531533A (ja) 2017-10-26
CN107073170A (zh) 2017-08-18
EP3209341A1 (en) 2017-08-30
JP6633628B2 (ja) 2020-01-22
MX2017005373A (es) 2017-07-28
EP3011981A1 (en) 2016-04-27
CA2964501A1 (en) 2016-04-28
EP3209341B1 (en) 2020-01-01
CA2964501C (en) 2023-05-16
AU2015334897A1 (en) 2017-05-18
KR102489773B1 (ko) 2023-01-17
US11241516B2 (en) 2022-02-08
BR112017008117B1 (pt) 2020-12-08
KR20170073673A (ko) 2017-06-28
CN107073170B (zh) 2021-06-29
AU2015334897B2 (en) 2019-08-01
WO2016062862A1 (en) 2016-04-28
ES2774792T3 (es) 2020-07-22

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Legal Events

Date Code Title Description
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 23/10/2015, OBSERVADAS AS CONDICOES LEGAIS.